Amino Acid Derivatives

Amino Acid Derivatives are bioactive molecules formed through chemical modifications or metabolic transformations of amino acids. They are widely present in living organisms and play crucial roles in physiological, psychological, and athletic performance.
The functions of these derivatives primarily include enhancing energy supply, regulating neurotransmitters, promoting fat metabolism, and reducing muscle damage. For example, creatine can increase muscle strength, enhance ATP resynthesis, and improve short-duration high-intensity exercise performance; tyrosine, as a precursor of dopamine and norepinephrine, helps enhance cognitive function and improve mood, particularly in sleep deprivation conditions, exhibiting anti-fatigue effects; carnitine facilitates fatty acid oxidation in the heart and skeletal muscles, improving endurance performance; HMB (β-hydroxy-β-methylbutyrate) reduces muscle breakdown and promotes muscle mass gain; while taurine exhibits antioxidant and antihypertensive properties and reduces oxidative stress induced by exercise.
Metabolic abnormalities or improper supplementation of amino acid derivatives may be associated with various diseases. For instance, tyrosine metabolism disorders can disrupt neurotransmitter balance, potentially leading to depression or stress-related disorders; elevated ADMA (asymmetric dimethylarginine) levels can inhibit nitric oxide synthesis, increasing the risk of cardiovascular diseases; carnitine deficiency is linked to certain genetic muscle disorders, impairing fat metabolism and energy production. Additionally, HMB may help slow muscle loss under specific conditions, while taurine intake is associated with improved cardiovascular health. Although some of the effects of these derivatives remain debated, they hold significant potential applications in sports nutrition, neurological regulation, and metabolic health.

References:

[1]. Luckose F, et al. Effects of amino acid derivatives on physical, mental, and physiological activities. Crit Rev Food Sci Nutr. 2015;55(13):1793-807. [Content Brief]

Amino Acid Derivatives Chemical (1)

Amino Acid Derivatives Related Products (1536):

Cat. No.	Product Name	Effect	Purity	Chemical Structure

HY-W004083

Boc-D-Asp(OBzl)-OH		99.63%
Boc-D-Asp(OBzl)-OH is an aspartic acid derivative.

HY-W002578

N-Carbobenzyloxy--amino-L-alanine		98.61%
N-Carbobenzyloxy--amino-L-alanine is an alanine derivative.

HY-W141815

Boc-Pen(Mob)-OH		99.88%
Boc-Pen(Mob)-OH is a phenylalanine derivative.

HY-W048828

((Benzyloxy)carbonyl)-L-alanyl-L-valine
((Benzyloxy)carbonyl)-L-alanyl-L-valine is a valine derivative.

HY-W039763

2-Amino-3-(naphthalen-1-yl)propanoic acid		98.47%
2-Amino-3-(naphthalen-1-yl)propanoic acid is an alanine derivative.

HY-77132

Z-Ala-OSu
Z-Ala-OSu is an alanine derivative.

HY-W018628

(S)-2-((tert-Butoxycarbonyl)amino)-2-cyclopentylacetic acid
(S)-2-((tert-Butoxycarbonyl)amino)-2-cyclopentylacetic acid is a Glycine (HY-Y0966) derivative.

HY-W014505

N-(4-Aminobenzoyl)-beta-alanine		99.35%
N-(4-Aminobenzoyl)-beta-alanine is an alanine derivative.

HY-30231

Z-Asp(OBzl)-OH		99.85%
Z-Asp(OBzl)-OH is an aspartic acid derivative.

HY-W052493

2-Amino-3-(4-hydroxy-3,5-diiodophenyl)propanoic acid
2-Amino-3-(4-hydroxy-3,5-diiodophenyl)propanoic acid is a tyrosine derivative.

HY-15400

Boc-D-Thr(Bzl)-OH		≥98.0%
Boc-D-Thr(Bzl)-OH is a threonine derivative.

HY-W009648

O-tert-Butylthreoninetert-butyl ester		99.89%
O-tert-Butylthreoninetert-butyl ester is a threonine derivative.

HY-W011472

H-D-Phe(4-I)-OH		99.90%
H-D-Phe(4-I)-OH is a phenylalanine derivative.

HY-W014097

Boc-Leucinol
Boc-Leucinol is a leucine derivative.

HY-79295

N-BOC-3-Fluoro-D-phenylalanine		99.67%
N-BOC-3-Fluoro-D-phenylalanine is a phenylalanine derivative.

HY-W015233

H-D-Asp(OtBu)-OH		99.91%
H-D-Asp(OtBu)-OH is an aspartic acid derivative.

HY-W042008

H-D-Phg(4-Cl)-OH
H-D-Phg(4-Cl)-OH is a Glycine (HY-Y0966) derivative.

HY-41631

Boc-Pyr-Oet		≥98.0%
Boc-Pyr-Oet is a derivative of L-Pyroglutamic acid (HY-76082). Boc-Pyr-Oet can be used for the synthesis of agents or other compounds.

HY-148207

S-Benzylglutathione		98.86%
S-Benzylglutathione is a competitive glutathionase inhibitor. S-Benzylglutathione is converted to the corresponding cysteine derivatives by rat kidney microsomes. S-Benzylglutathione can be used for the research of metabolic breakdown of glutathione by the glutathionase system.

HY-W048831

(tert-Butoxycarbonyl)-L-valyl-L-valine
(tert-Butoxycarbonyl)-L-valyl-L-valine is a valine derivative.

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