Amino Acid Derivatives

Amino Acid Derivatives are bioactive molecules formed through chemical modifications or metabolic transformations of amino acids. They are widely present in living organisms and play crucial roles in physiological, psychological, and athletic performance.
The functions of these derivatives primarily include enhancing energy supply, regulating neurotransmitters, promoting fat metabolism, and reducing muscle damage. For example, creatine can increase muscle strength, enhance ATP resynthesis, and improve short-duration high-intensity exercise performance; tyrosine, as a precursor of dopamine and norepinephrine, helps enhance cognitive function and improve mood, particularly in sleep deprivation conditions, exhibiting anti-fatigue effects; carnitine facilitates fatty acid oxidation in the heart and skeletal muscles, improving endurance performance; HMB (β-hydroxy-β-methylbutyrate) reduces muscle breakdown and promotes muscle mass gain; while taurine exhibits antioxidant and antihypertensive properties and reduces oxidative stress induced by exercise.
Metabolic abnormalities or improper supplementation of amino acid derivatives may be associated with various diseases. For instance, tyrosine metabolism disorders can disrupt neurotransmitter balance, potentially leading to depression or stress-related disorders; elevated ADMA (asymmetric dimethylarginine) levels can inhibit nitric oxide synthesis, increasing the risk of cardiovascular diseases; carnitine deficiency is linked to certain genetic muscle disorders, impairing fat metabolism and energy production. Additionally, HMB may help slow muscle loss under specific conditions, while taurine intake is associated with improved cardiovascular health. Although some of the effects of these derivatives remain debated, they hold significant potential applications in sports nutrition, neurological regulation, and metabolic health.

References:

[1]. Luckose F, et al. Effects of amino acid derivatives on physical, mental, and physiological activities. Crit Rev Food Sci Nutr. 2015;55(13):1793-807. [Content Brief]

Amino Acid Derivatives Chemical (1)

Amino Acid Derivatives Related Products (1589):

Cat. No.	Product Name	Effect	Purity	Chemical Structure

HY-W008086

H-Thr-OMe hydrochloride
H-Thr-OMe.HCl is a threonine derivative.

HY-W008077

(S)-2-Amino-3,3-diphenylpropanoic acid		99.94%
(S)-2-Amino-3,3-diphenylpropanoic acid is an alanine derivative.

HY-W051350

H-D-Thr(tBu)-OH		99.56%
H-D-Thr(tBu)-OH is a threonine derivative.

HY-W009592A

Glycyltyrosine dihydrate		99.78%
Glycyltyrosine dihydrate is a synthetic dipeptide that can be used as a food additive for tyrosine supplementation.

HY-P4106A

Tat-GluR23Y, scrambled TFA		99.47%
Tat-GluR23Y, scrambled TFA is the scrambled peptide of Tat-GluR23Y (HY-P2259). Tat-GluR23Y is a synthetic peptide containing tyrosine residues that inhibit AMPAR endocytosis and is effective in the research of long-term depression (LTD).

HY-79294

H-D-Phe(3-F)-OH		99.85%
H-D-Phe(3-F)-OH is a phenylalanine derivative.

HY-W012707

(S)-2-Amino-2,3-dimethylbutanoic acid		99.90%
(S)-2-Amino-2,3-dimethylbutanoic acid is a valine derivative.

HY-W011325

Z-D-tyrosine
Z-D-tyrosine is a tyrosine derivative.

HY-W062304

Boc-D-Arg(Pbf)-OH		99.31%
Boc-D-Arg(Pbf)-OH is an arginine derivative.

HY-W047902

L-Isoleucylglycine
L-Isoleucylglycine is a Glycine (HY-Y0966) derivative.

HY-W040438

(S)-Methyl 2-((tert-butoxycarbonyl)amino)-3-(3,4-dihydroxyphenyl)propanoate
(S)-Methyl 2-((tert-butoxycarbonyl)amino)-3-(3,4-dihydroxyphenyl)propanoate is a tyrosine derivative.

HY-W012921

(R)-Pyrrolidine-2-carboxamide		≥98.0%
(R)-Pyrrolidine-2-carboxamide is a proline derivative.

HY-I0124

2-((3-Fluoro-4-(methylcarbamoyl)phenyl)amino)-2-methylpropanoic acid		99.66%
2-((3-Fluoro-4-(methylcarbamoyl)phenyl)amino)-2-methylpropanoic acid is an alanine derivative.

HY-W022220

H-His(trt)-OMe hydrochloride
H-His(trt)-OMe hydrochloride is a histidine derivative.

HY-W053699

N-p-Tosylglycine		98.21%
N-p-Tosylglycine is a Glycine (HY-Y0966) derivative.

HY-W042478

(S)-3-(Boc-amino)-4-phenylbutyric acid
(S)-3-(Boc-amino)-4-phenylbutyric acid is a phenylalanine derivative.

HY-W012104

Z-D-Ser-OH		99.54%
Z-D-Ser-OH is a serine derivative.

HY-W011089

Fmoc-β-HoLeu-OH		98.43%
Fmoc-β-HoLeu-OH is a leucine derivative.

HY-W018850

L-Isovaline		99.90%
L-Isovaline is a valine derivative.

HY-W111382

2,2'-((((9H-Fluoren-9-yl)methoxy)carbonyl)azanediyl)diacetic acid		99.87%
2,2'-((((9H-Fluoren-9-yl)methoxy)carbonyl)azanediyl)diacetic acid is a Glycine (HY-Y0966) derivative.

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