Amino Acid Derivatives

Amino Acid Derivatives are bioactive molecules formed through chemical modifications or metabolic transformations of amino acids. They are widely present in living organisms and play crucial roles in physiological, psychological, and athletic performance.
The functions of these derivatives primarily include enhancing energy supply, regulating neurotransmitters, promoting fat metabolism, and reducing muscle damage. For example, creatine can increase muscle strength, enhance ATP resynthesis, and improve short-duration high-intensity exercise performance; tyrosine, as a precursor of dopamine and norepinephrine, helps enhance cognitive function and improve mood, particularly in sleep deprivation conditions, exhibiting anti-fatigue effects; carnitine facilitates fatty acid oxidation in the heart and skeletal muscles, improving endurance performance; HMB (β-hydroxy-β-methylbutyrate) reduces muscle breakdown and promotes muscle mass gain; while taurine exhibits antioxidant and antihypertensive properties and reduces oxidative stress induced by exercise.
Metabolic abnormalities or improper supplementation of amino acid derivatives may be associated with various diseases. For instance, tyrosine metabolism disorders can disrupt neurotransmitter balance, potentially leading to depression or stress-related disorders; elevated ADMA (asymmetric dimethylarginine) levels can inhibit nitric oxide synthesis, increasing the risk of cardiovascular diseases; carnitine deficiency is linked to certain genetic muscle disorders, impairing fat metabolism and energy production. Additionally, HMB may help slow muscle loss under specific conditions, while taurine intake is associated with improved cardiovascular health. Although some of the effects of these derivatives remain debated, they hold significant potential applications in sports nutrition, neurological regulation, and metabolic health.

References:

[1]. Luckose F, et al. Effects of amino acid derivatives on physical, mental, and physiological activities. Crit Rev Food Sci Nutr. 2015;55(13):1793-807. [Content Brief]

Amino Acid Derivatives Chemical (1)

Amino Acid Derivatives Related Products (1582):

Cat. No.	Product Name	Effect	Purity	Chemical Structure

HY-W130212

(R)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(2-(trifluoromethyl)phenyl)propanoic acid		99.58%
(R)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(2-(trifluoromethyl)phenyl)propanoic acid is a phenylalanine derivative.

HY-W011703

Z-Asp-OH		99.02%
Z-Asp-OH is an aspartic acid derivative.

HY-W008544

D-Isovaline
D-Isovaline is a valine derivative.

HY-W011084

Fmoc-L-glutamine		99.15%
Fmoc-L-glutamine is a glutamine derivative.

HY-W012255

Ethyl L-phenylalaninate hydrochloride		99.79%
Ethyl L-phenylalaninate hydrochloride is a phenylalanine derivative.

HY-W010976

Fmoc-D-Lys-OH.HCl		99.66%
Fmoc-D-Lys-OH.HCl is a lysine derivative.

HY-76962

(S)-2-Methylpyrrolidine-2-carboxylic acid		≥98.0%
(S)-2-Methylpyrrolidine-2-carboxylic acid is a proline derivative.

HY-W041999

H-D-Asp(OMe)-OMe.HCl
H-D-Asp(OMe)-OMe.HCl is an aspartic acid derivative.

HY-W008308

H-Ser(Bzl)-OH		99.95%
H-Ser(Bzl)-OH is a serine derivative.

HY-W018741

Boc-Asp-OMe
Boc-Asp-OMe is an aspartic acid derivative.

HY-W012883

2-((2-Aminoethyl)amino)acetic acid		99.89%
2-((2-Aminoethyl)amino)acetic acid is a Glycine (HY-Y0966) derivative.

HY-W048682

Fmoc-1-methyl-L-histidine		99.06%
Fmoc-1-methyl-L-histidine is a Fmoc protected amino acid and amino acid-containing building block. Fmoc-1-methyl-L-histidine can be used in the production of ε-nitrogen-ligated copper centers in copper nitrite reductases. Fmoc-1-methyl-L-histidine can also be used as an intermediate for peptide synthesis.

HY-79123

(2S,4R)-1-((9H-Fluoren-9-yl)methyl) 2-methyl 4-hydroxypyrrolidine-1,2-dicarboxylate		98.74%
(2S,4R)-1-((9H-Fluoren-9-yl)methyl) 2-methyl 4-hydroxypyrrolidine-1,2-dicarboxylate is a proline derivative.

HY-W004114

N-Acetyl-L-proline		99.92%
N-Acetyl-L-proline is aproline derivatives.

HY-77026

(S)-Ethyl 2-amino-4-fluoro-4-methylpentanoate sulfate		99.88%
(S)-Ethyl 2-amino-4-fluoro-4-methylpentanoate sulfate is a leucine derivative.

HY-W051093

(S)-1-(tert-Butoxycarbonyl)-2-methylpyrrolidine-2-carboxylic acid		99.81%
(S)-1-(tert-Butoxycarbonyl)-2-methylpyrrolidine-2-carboxylic acid is a proline derivative.

HY-W016426

H-D-Ala-OtBu.HCl		≥98.0%
H-D-Ala-OtBu.HCl is an alanine derivative.

HY-N6655

DL-Methionine methylsulfonium chloride		≥98.0%
DL-methionine methylsulfonium chloride is a naturally occurring methionine derivative. DL-methionine methylsulfonium chloride protects gastric mucosal from ethanol-induced damage.

HY-W047799

Boc-Dap(Boc)-OH
Fmoc-Phe(4-CONH2)-OH is an amino acid derivative with an Fmoc protecting group, which can be used to synthesize a small-sized HTLV-I protease inhibitor with hydrophilicity.

HY-W009486

H-Tyr-Ala-OH		99.86%
H-Tyr-Ala-OH (Tyrosylalanine) is a L-tyrosine- and L-alanine-containing dipeptide.

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