2. Signaling Pathways
  3. Cell Cycle/DNA Damage
    Epigenetics
  4. PARP
  5. PARP14 Isoform
  6. PARP14 Degrader

PARP14 Degrader

PARP14 Degrader (1):

Cat. No. Product Name Effect Purity
  • HY-173679
    RBN012811
    		Degrader 98.79%
    RBN012811 is a selectively PARP14 PROTAC degrader with a DC50 of 5 nM in KYSE-270 cells. RBN012811 significantly decreases IL-10 expression in IL-4 stimulated macrophages. Pink: PARP14 ligand (HY-150947); Blue: CRBN ligase ligand (HY-10984); Black: linker