1. Signaling Pathways
  2. Metabolic Enzyme/Protease
  3. Endogenous Metabolite

Endogenous Metabolite

Metabolite results when a drug is metabolized into a modified form which continues to produce effects. A metabolome in a given body fluid is influenced by endogenous factors such as age, sex, body composition and genetics as well as underlying pathologies.The levels of the enormous array of unique small-molecule metabolites are usually kept tightly regulated by the activity of a very large array of enzymes and transporters responsible for the production, transformation, degradation, and compartmentalization of these small molecules.The levels of the endogenous small molecules present in the brain are normally tightly regulated.

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-113295
    Salicyluric acid
    99.79%
    Salicyluric acid is an endogenous metabolite.
    Salicyluric acid
  • HY-W017462
    Creatine monohydrate
    99.98%
    Creatine monohydrate, an endogenous amino acid derivative, plays an important role in cellular energy, especially in muscle and brain.
    Creatine monohydrate
  • HY-N7719
    Oosporein
    99.16%
    Oosporein is a microbial metabolite and a red crystalline toxin produced by various fungi. Oosporein can promote the reproduction of fungi in host bodies by inhibiting insect immunity, and possesses multiple activities such as antibacterial, antiviral (HSV), and insecticidal effects. Oosporein can inhibit plant growth. In addition, Oosporein can also induce apoptosis, cell membrane damage, oxidative stress, and mitochondrial damage. Oosporein has certain antitumor activity.
    Oosporein
  • HY-P2752
    Lipoprotein lipase, Pseudomonas sp
    Lipoprotein lipase, Pseudomonas sp (LPL) is a multifunctional enzyme from adipose tissue, heart and skeletal muscle, islets and macrophages. Lipoprotein lipase promotes normal lipoprotein metabolism, delivery and utilization of tissue-specific substrates. Lipoprotein lipase catalyzes the rate-limiting step of lipids in blood circulation.
    Lipoprotein lipase, Pseudomonas sp
  • HY-N0623S9
    L-Tryptophan-d3
    99.98%
    L-Tryptophan-d3 is the deuterium labeled L-Tryptophan. L-Tryptophan (Tryptophan) is an essential amino acid that is the precursor of serotonin, melatonin, and vitamin B3.
    L-Tryptophan-d<sub>3</sub>
  • HY-113286
    4-Guanidinobutanoic acid
    98.0%
    4-Guanidinobutanoic acid is a common urinary metabolite and arginine metabolite. 4-Guanidinobutanoic acid can be used in the research of fibromyalgia.
    4-Guanidinobutanoic acid
  • HY-114297
    Zymosterol
    99.47%
    Zymosterol is a Cholesterol (HY-N0322) biosynthesis metabolite. Zymosterol, a precursor of Cholesterol, is found mostly in the plasma membrane. Zymosterol circulates within the cell.
    Zymosterol
  • HY-N0086S
    N6-Methyladenosine-d3
    99.97%
    N6-Methyladenosine-d3 (6-Methyladenosine-d3; N-Methyladenosine-d3) is a deuterium labeled N6-Methyladenosine (HY-N0086). N6-Methyladenosine is the most prevalent internal (non-cap) modification present in the messenger RNA (mRNA) of all higher eukaryotes. N6-Methyladenosine can modifies viral RNAs and has antiviral activities.
    N6-Methyladenosine-d<sub>3</sub>
  • HY-136497
    Coenzyme FO
    98.90%
    Coenzyme FO, a deazaflavin chromophore, acts as an important hydride acceptor/donor in the central methanogenic pathway.
    Coenzyme FO
  • HY-N0367
    Trans-Anethole
    99.70%
    Trans-Anethole ((E)-Anethole) is an orally active phenylpropene derivative found in Foeniculum vulgare that is estrogenic at low concentrations and cytotoxic at high concentrations in tumor cell lines. Trans-Anethole also has anti-aflatoxin, anti-thrombotic and anti-diabetic activities. Trans-Anethole is an important odor component in plants such as fennel, myrtle, liquorice, and camphor.
    Trans-Anethole
  • HY-12326B
    c-di-AMP diammonium
    99.36%
    c-di-AMP diammonium is a STING agonist, which binds to the transmembrane protein STING thereby activating the TBK3-IRF3 signaling pathway, subsequently triggering the production of type I IFN and TNF. c-di-AMP diammonium is also a bacterial second messenger, which regulates cell growth, survival, and virulence, primarily within Gram-positive bacteria, and also regulates host immune response. c-di-AMP diammonium acts as a potent mucosal adjuvant stimulating both humoral and cellular responses.
    c-di-AMP diammonium
  • HY-N0598
    Ginsenoside F1
    99.0%
    Ginsenoside F1, an enzymatically modified derivative of Ginsenoside Rg1, demonstrates competitive inhibition of CYP3A4 activity and weaker inhibition of CYP2D6 activity.
    Ginsenoside F1
  • HY-B0157
    Ketotifen
    99.74%
    Ketotifen (HC 20-511) is an orally active second-generation noncompetitive histamine 1 (H1) receptor blocker and mast cell stabilizer. Ketotifen can block 6-phosphogluconate dehydrogenase (PGD) in vitro. Ketotifen also has antiviral activity against SARS-CoV-2 and Influenza virus. Ketotifen can be used to the research of autoimmune encephalomyelitis (EAE) and asthma attack prevention.
    Ketotifen
  • HY-W017230
    L-Cysteinesulfinic acid monohydrate
    99.81%
    L-Cysteinesulfinic acid monohydrate is a potent agonist at several rat metabotropic glutamate receptors (mGluRs) with pEC50s of 3.92, 4.6, 3.9, 2.7, 4.0, and 3.94 for mGluR1, mGluR5, mGluR2, mGluR4, mGluR6, and mGluR8, respectively.
    L-Cysteinesulfinic acid monohydrate
  • HY-N0351S1
    p-Coumaric acid-d6
    98.88%
    p-Coumaric acid-d6 is the deuterium labeled p-Coumaric acid (HY-N0351). p-Coumaric acid is the abundant isomer of cinnamic acid which has antitumor and anti-mutagenic activities.
    p-Coumaric acid-d<sub>6</sub>
  • HY-101404
    DL-Homocysteine thiolactone hydrochloride
    99.97%
    DL-Homocysteine thiolactone hydrochloride is a cyclic amino acid derivative that exhibits root-growth inhibitory activity.
    DL-Homocysteine thiolactone hydrochloride
  • HY-W127744
    Chlorophyll a
    98%
    Chlorophyll a is a key green pigment in oxygenic photosynthesis. Chlorophyll a has the dual functions of light harvesting and converting light energy into chemical energy through charge separation in photosystems I and II. Chlorophyll a has antioxidant activity and anti-inflammatory effects. Chlorophyll a can be used in researches for photosynthetic mechanisms and inflammation-related diseases.
    Chlorophyll a
  • HY-P2871
    α-Galactosidase, Aspergillus niger
    α-Galactosidase, Aspergillus niger (EC 3.2.1.22), that is, α-galactosidase, is a glycoside hydrolase that widely exists in animals, plants and microorganisms, and is often used in biochemical research. α-Galactosidase catalyzes the hydrolysis of α-1,6-linked terminal galactose residues, including galactooligosaccharides, galactomannans, and galactolipids. Catalyzes many catabolic processes including cleavage of glycoproteins, glycolipids and polysaccharides.
    α-Galactosidase, Aspergillus niger
  • HY-113020
    21-Hydroxypregnenolone
    98.05%
    21-Hydroxypregnenolone is an essential intermediate in corticosterone synthesis.
    21-Hydroxypregnenolone
  • HY-N0771S3
    L-Isoleucine-d10
    98.0%
    L-Isoleucine-d10 is the deuterium labeled L-Isoleucine. L-isoleucine is a nonpolar hydrophobic amino acid. L-Isoleucine is an essential amino acid.
    L-Isoleucine-d<sub>10</sub>
Cat. No. Product Name / Synonyms Application Reactivity