2. Signaling Pathways
  3. Metabolic Enzyme/Protease
  4. Endogenous Metabolite

Endogenous Metabolite

Endogenous Metabolite

Related Products

PDF 48.35 MB

Metabolite results when a drug is metabolized into a modified form which continues to produce effects. A metabolome in a given body fluid is influenced by endogenous factors such as age, sex, body composition and genetics as well as underlying pathologies.The levels of the enormous array of unique small-molecule metabolites are usually kept tightly regulated by the activity of a very large array of enzymes and transporters responsible for the production, transformation, degradation, and compartmentalization of these small molecules.The levels of the endogenous small molecules present in the brain are normally tightly regulated.

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-135867E
    NHC-triphosphate tetraammonium
    NHC-triphosphate tetraammonium is an active phosphorylated intracellular metabolite of β-d-N4-Hydroxycytidine (NHC) (HY-125033) as a triphosphate form. NHC-triphosphate tetraammonium is a weak alternative substrate for the viral polymerase and can be incorporated into HCV replicon RNA.
    NHC-triphosphate tetraammonium
  • HY-N7493
    N-acetyldopamine
    		99.23%
    N-acetyldopamine is a sepiapterin reductase inhibitor. N-acetyldopamine is a catecholamine that is used by insects as sclerotizing precursors to harden their cuticle. N-acetyldopamine can attenuate LPS-stimulated TNF-α production and superoxide production in THP-1 cells.
    N-acetyldopamine
  • HY-N0492S
    α-Lipoic Acid-d5
    α-Lipoic Acid-d5 is the deuterium labeled α-Lipoic Acid. α-Lipoic Acid is an antioxidant, which is an essential cofactor of mitochondrial enzyme complexes. α-Lipoic Acid inhibits NF-κB-dependent HIV-1 LTR activation. α-Lipoic Acid induces endoplasmic reticulum (ER) stress-mediated apoptosis in hepatoma cells.
    α-Lipoic Acid-d<sub>5</sub>
  • HY-Y0068
    N-Acetyl-L-phenylalanine
    		99.98%
    N-Acetyl-L-phenylalanine (N-Acetylphenylalanine) is a principal acylamino acid. N-Acetyl-L-phenylalanine can be synthesized from L-phenylalanine and acetyl-CoA. N-Acetyl-L-phenylalanine can be used in kidney research.
    N-Acetyl-L-phenylalanine
  • HY-P2809
    Malic dehydrogenase, microorganism
    Malate dehydrogenase (EC 1.1.1.37) (MDH) catalyzes the mutual conversion of oxaloacetate and malate, and is associated with the oxidation/reduction of dinucleotide coenzymes.
    Malic dehydrogenase, microorganism
  • HY-113116
    Sphinganine 1-phosphate
    		≥99.0%
    Sphinganine 1-phosphate (D-erythro-Dihydrosphingosine 1-phosphate) is a polar sphingolipid metabolite that regulates cell migration, differentiation, survival and complex physiological processes.
    Sphinganine 1-phosphate
  • HY-W012974
    3-Aminoisobutyric acid
    		≥98.0%
    3-Aminoisobutyric acid (β-Aminoisobutyric acid) has anti-inflammatory and antioxidant effects. 3-Aminoisobutyric acid increases the expression of brown adipocyte-specific genes in white adipose tissue and fatty acid β-oxidation in hepatocytes. 3-Aminoisobutyric acid attenuates insulin resistance and inflammation induced by palmitate or a high fat diet via an AMPK-PPARδ-dependent pathway in mice. 3-Aminoisobutyric acid is a catabolic metabolite of thymine and valine in skeletal muscle.
    3-Aminoisobutyric acid
  • HY-Y0839
    Levulinic acid
    		99.71%
    Levulinic acid is a precursor for the synthesis of biofuels, such as ethyl levulinate. Levulinic acid is also a 5-keto-pentanoic acid. Levulinic acid can be utilized by the cells as a cosubstrate for biopolymer synthesis. Levulinic acid can be used in antibacterial research.
    Levulinic acid
  • HY-W010104A
    Methionine sulfoxide
    		99.74%
    Methionine sulfoxide is an oxidation product of methionine with reactive oxygen species and can be regarded as a biomarker of oxidative stress in vivo.
    Methionine sulfoxide
  • HY-N0473S
    L-Tyrosine-d4
    		98.0%
    L-Tyrosine-d4 is a deuterium labeled L-Tyrosine. L-Tyrosine is a non-essential amino acid which can inhibit citrate synthase activity in the posterior cortex.
    L-Tyrosine-d<sub>4</sub>
  • HY-I1060
    L-Alloisoleucine
    		98.7%
    L-Alloisoleucine is a stereoisomer of L-isoleucine. L-Alloisoleucine can be used in skeletal muscle research.
    L-Alloisoleucine
  • HY-113266
    Valerylcarnitine
    		≥99.0%
    Valerylcarnitine is an endogenous metabolite, belonging to the short-chain acylcarnitines.
    Valerylcarnitine
  • HY-W014589
    2,4-Di-tert-butylphenol
    		99.97%
    2,4-Di-tert-butylphenol (2,4-DTBP) is an orally active RXRα activator and a human estrogen receptor ligand with anti-inflammatory and antioxidant activities, which can induce apoptosis in tumor cells. 2,4-Di-tert-butylphenol can activate the RXRα subtype in LXRα/RXRα, PPARγ/RXRα, and hormone receptor β/RXRα. 2,4-Di-tert-butylphenol also has antiviral and antifungal activities and has the potential to inhibit Aβ-induced neurotoxicity. 2,4-Di-tert-butylphenol can be used as an intermediate in the preparation of antioxidants and UV stabilizers, and is also used in the manufacture of drugs and fragrances.
    2,4-Di-tert-butylphenol
  • HY-P2921
    Urate oxidase, Microorganism
    Urate oxidase, Microorganism (Uox), i.e., uricase, is often used in biochemical studies. Urate oxidase is a peroxisomal enzyme that catalyzes the oxidation of uric acid to allantoin in most mammals.
    Urate oxidase, Microorganism
  • HY-W017782
    2,5-Furandimethanol
    		99.62%
    2,5-Furandimethanol (2,5-Bis(hydroxymethyl)furan) is a building block for the enzymatic synthesis of bio-based polyesters. 2,5-Furandimethanol is also a metabolite of Phellinus linteus. 2,5-Furandimethanol affects leukemia. 2,5-Furandimethanol can be used in fungal infection research.
    2,5-Furandimethanol
  • HY-W001132S4
    Indole-d7
    		99.94%
    Indole-d7 is the deuterium labeled Indole. Indole is an endogenous metabolite.
    Indole-d<sub>7</sub>
  • HY-B0642
    Isosorbide mononitrate
    		99.95%
    Isosorbide mononitrate (Isosorbide-5-mononitrate) is an orally active nitric acid compound used for angina pectoris by dilating blood vessels and lowering blood pressure. Isosorbide mononitrate increases the viability and proliferation of HUVECs by decreasing Apoptosis and elevated the expressions of vedf, kdrl, pdgfr in zebrafish embryos. Isosorbide mononitrate is promising for research of heart failure and coronary heart disease.
    Isosorbide mononitrate
  • HY-B2236
    DL-Lysine
    		99.66%
    DL-Lysine is a racemic mixture of the D-Lysine and L-Lysine. Lysine is an α-amino acid that is used in the biosynthesis of proteins.
    DL-Lysine
  • HY-P2857
    Amyloglucosidase, Aspergillus niger
    Amyloglucosidase, Aspergillus niger is an enzyme derived from many sources including plants, animals and microorganisms, can be use for industrial production. Amyloglucosidase can be widely used for starch saccharification, brewing and distilling industry.
    Amyloglucosidase, Aspergillus niger
  • HY-B0935
    Benzyl benzoate
    		99.94%
    Benzyl benzoate (Phenylmethyl benzoate) is an orally active anti-scabies agent, acaricide (EC50= 0.06 g/m2) and fungicide. Benzyl benzoate is an angiotensin II (Ang II) inhibitor with antihypertensive effects. Benzyl benzoate can be used in perfumes, pharmaceuticals and the food industry.
    Benzyl benzoate
Cat. No. Product Name / Synonyms Application Reactivity