2. Signaling Pathways
  3. Metabolic Enzyme/Protease
  4. Endogenous Metabolite

Endogenous Metabolite

Endogenous Metabolite

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Metabolite results when a drug is metabolized into a modified form which continues to produce effects. A metabolome in a given body fluid is influenced by endogenous factors such as age, sex, body composition and genetics as well as underlying pathologies.The levels of the enormous array of unique small-molecule metabolites are usually kept tightly regulated by the activity of a very large array of enzymes and transporters responsible for the production, transformation, degradation, and compartmentalization of these small molecules.The levels of the endogenous small molecules present in the brain are normally tightly regulated.

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-N0060A
    Ferulic acid sodium
    		99.88%
    Ferulic acid sodium is a novel fibroblast growth factor receptor 1 (FGFR1) inhibitor with IC50s of 3.78 and 12.5 μM for FGFR1 and FGFR2, respectively.
    Ferulic acid sodium
  • HY-N0467
    Rebaudioside C
    		99.90%
    Rebaudioside C (Dulcoside B) is an orally effective natural sweetener that cannot pass the blood-brain barrier and selectively binds to human sweet taste receptors (TAS1R2/TAS1R3). The sweetness of Rebaudioside C is about 20-30 times that of sucrose, and its sweetness activity depends on the C-16/C-17 double bond structure and specific aglycones. The glycoside structure in the Rebaudioside C molecule can bind to the sweet taste receptor, activate the taste signal transduction pathway, and produce sweetness perception.
    Rebaudioside C
  • HY-N0457A
    L-Chicoric Acid
    		99.85%
    L-Chicoric Acid ((-)-Chicoric acid) is a dicaffeoyltartaric acid and a potent, selective and reversible HIV-1 integrase inhibitor with an IC50 of ~100 nM. L-Chicoric Acid inhibits HIV-1 replication in tissue culture.
    L-Chicoric Acid
  • HY-W017007
    3-Methyl-L-histidine
    		99.98%
    3-Methyl-L-histidine is an endogenous amino acid that can be found in actin and myosin.
    3-Methyl-L-histidine
  • HY-N0394S1
    L-Cystine-d4
    		98.0%
    L-Cystine-d4 is the deuterium labeled L-Cystine. L-Cystine is an amino acid and intracellular thiol, which plays a critical role in the regulation of cellular processes.
    L-Cystine-d<sub>4</sub>
  • HY-128850
    N-Acetyl-D-mannosamine
    		99.99%
    N-Acetyl-D-mannosamine (ManNAc) is an oral active sialic acid precursor that can prevent hypertension by increasing sialylation of IgG, making it a promising candidate for cardiovascular disease research. Additionally, N-Acetyl-D-mannosamine can activate hypocretin (HCRT) gene expression in orexin neurons and improve neurodegeneration caused by aging, offering potential avenues for research in neurological disorders.
    N-Acetyl-D-mannosamine
  • HY-W018555
    D-Cysteine
    		≥98.0%
    D-Cysteine, the D-isomer of cysteine, is an orally active antibacterial agent and a regulator of neural progenitor cell proliferation. D-Cysteine can inhibit Escherichia coli, Streptococcus mutans, and Streptococcus sanguinis. The no-observed-adverse-effect level of D-Cysteine in rats should be less than 500 mg/kg/day.
    D-Cysteine
  • HY-113136
    1-Methylguanosine
    		99.57%
    1-Methylguanosine (N1-Methylguanosine) is a methylated nucleoside originating from RNA degradation. 1-Methylguanosine is a tumour marker.
    1-Methylguanosine
  • HY-129630
    Tetrahydrocortisol
    		99.91%
    Tetrahydrocortisol is cortisol metabolite. The urinary Tetrahydrocortisol/Tetrahydrocortisone ratio decreases with increasing 11β-hydroxysteroid dehydrogenase (11β-HSD) activity.
    Tetrahydrocortisol
  • HY-113162
    Bovinic acid
    		≥99.0%
    Bovinic acid is a conjugated linoleic acid with anticarcinogenic and anti-atherogenic activities. Bovinic acid is a major constituent of the plant C. lacrima-joby. Bovinic acid possesses insectividal activity against the potato bug and herbicidal activity against wild oat, sun spurge, goosefoot, canary grass, and knotweed.
    Bovinic acid
  • HY-131368
    α,α-Trehalose 6-phosphate potassium
    		99.00%
    α,α-Trehalose 6-phosphate (Tre6P) potassium is an endogenous metabolite. α,α-Trehalose 6-phosphate is a 6-phosphate derivative of α,α′-trehalose. α,α-Trehalose 6-phosphate is rapidly converted to the pathway end product, α,α′-trehalose, through the action of Tre6P phosphatase (T6PP).
    α,α-Trehalose 6-phosphate potassium
  • HY-113283
    Homogentisic acid
    		99.46%
    Homogentisic acid is a specific metabolite that accumulates in the urine and serum. Homogentisic acid can be used for diagnosis of alkaptonuria. Homogentisic acid is a phenolic acid.
    Homogentisic acid
  • HY-134222A
    N-Acetylserine
    		98.0%
    N-Acetylserine (N-Acetyl-L-serine) is a physiological inducer of cysteine biosynthesis and activator of CysB. N-Acetylserine can bind to the CysB apoprotein. N-Acetylserine stimulates cysJIH transcription in vitro. N-Acetylserine can be used in the research of SARS-CoV-2 infection.
    N-Acetylserine
  • HY-W011824
    2′-O-Methyluridine
    		99.81%
    2’-O-Methyluridine is a modified nucleoside that can be found in T. thermophile tRNA. 2’-O-Methyluridine can be incorporated into siRNA targeting the gene encoding apolipoprotein B, which decreases ApoB protein levels in HepG2 and prevents IFN-α production in isolated human PBMCs. 2’-O-Methyluridine level in serum is decreased in patients with breast cancer.
    2′-O-Methyluridine
  • HY-N0010
    Geniposidic acid
    		98.87%
    Geniposidic acid is an effective anticancer and radioprotection agent.
    Geniposidic acid
  • HY-W004078
    4-Hydroxybenzylamine
    		99.80%
    4-Hydroxybenzylamine is an endogenous metabolite.
    4-Hydroxybenzylamine
  • HY-43470
    3α,12β-Dihydroxycholanoic acid
    3α,12β-Dihydroxycholanoic acid is a bile acid that can be isolated from urine specimens of healthy humans.
    3α,12β-Dihydroxycholanoic acid
  • HY-Y0337S5
    L-Cysteine-d3
    		99.2%
    L-Cysteine-d3 is the deuterium labeled L-Cysteine. L-Cysteine is a conditionally essential amino acid, which acts as a precursor for biologically active molecules such as hydrogen sulphide (H2S), glutathione and taurine. L-Cysteine suppresses ghrelin and reduces appetite in rodents and humans.
    L-Cysteine-d<sub>3</sub>
  • HY-W017316
    Terpinen-4-ol
    		98.58%
    Terpinen-4-ol (4-Carvomenthenol) is a naturally occurring monoterpene, and can be extracted from a variety of aromatic plants. Terpinen-4-ol is a potent bactericidal agent which possess antifungal , anti-inflammatory and antitumor properties as well, suggesting Terpinen-4-ol to be used for relevant research.
    Terpinen-4-ol
  • HY-128744
    Phosphonoacetic acid
    		98.0%
    Phosphonoacetic acid is an endogenous metabolite and antiviral agent. Phosphonoacetic acid is active against orthopoxviruses and herpes viruses. Phosphonoacetic acid can inhibit HSV DNA synthesis and virus-specific DNA polymerase activity, and affect the synthesis of late viral proteins.
    Phosphonoacetic acid
Cat. No. Product Name / Synonyms Application Reactivity