2. Signaling Pathways
  3. Metabolic Enzyme/Protease
  4. Endogenous Metabolite

Endogenous Metabolite

Endogenous Metabolite

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Metabolite results when a drug is metabolized into a modified form which continues to produce effects. A metabolome in a given body fluid is influenced by endogenous factors such as age, sex, body composition and genetics as well as underlying pathologies.The levels of the enormous array of unique small-molecule metabolites are usually kept tightly regulated by the activity of a very large array of enzymes and transporters responsible for the production, transformation, degradation, and compartmentalization of these small molecules.The levels of the endogenous small molecules present in the brain are normally tightly regulated.

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-P4605
    (Ile8)-Oxytocin
    		99.65%
    (Ile8)-Oxytocin is a neurohypophysial hormone mesotocin produced in marsupials.
    (Ile8)-Oxytocin
  • HY-N0568R
    Madecassoside (Standard)
    Madecassoside (Standard) is the analytical standard of Madecassoside. This product is intended for research and analytical applications. Madecassoside is a pentacyclic triterpene isolated from Centella asiatica and has anti-inflammatory properties. Antioxidant and anti-aging effects. Madecassoside is a pentacyclic triterpene isolated from Centella asiatica. Madecassoside is orally active and has inhibitory properties against inflammation, oxidation, apoptosis and autophagy. Madecassosid inhibits activities of p38 MAPK and NF-kB, exhibits an anti-apopototic property, activates Nrf2 expression to reduce the neurotoxicity[10]. Madecassoside can be used in endocrine diseases, cardiovascular diseases, skin diseases and other diseases.
    Madecassoside (Standard)
  • HY-78446
    KSD 2405
    		99.87%
    KSD 2405 is an endogenous metabolite.
    KSD 2405
  • HY-B0389S29
    D-Glucose-18O
    		99.9%
    D-Glucose-18O is the 18O labeled D-Glucose. D-Glucose (Glucose), a monosaccharide, is an important carbohydrate in biology. D-Glucose is a carbohydrate sweetener and critical components of the general metabolism, and serve as critical signaling molecules
    D-Glucose-<sup>18</sup>O
  • HY-N7140R
    Gamma-Linolenic acid (Standard)
    Gamma-Linolenic acid (Standard) is the analytical standard of Gamma-Linolenic acid. This product is intended for research and analytical applications. Gamma-linolenic acid (γ-Linolenic acid) is an omega-6 (n-6), 18 carbon (18C-) polyunsaturated fatty acid (PUFA) extracted from Perilla frutescens. Gamma-linolenic acid supplements could restore needed PUFAs and mitigate the disease.
    Gamma-Linolenic acid (Standard)
  • HY-N1443
    Demethylcantharidate disodium
    		≥98.0%
    Demethylcantharidate disodium, an endogenous metabolite, induces apoptosis in hepatocellular carcinoma cells via ER stress. Demethylcantharidate disodium shows excellent anticancer activity against multiple types of cancer.
    Demethylcantharidate disodium
  • HY-B0964A
    Riboflavin phosphate
    Riboflavine phosphate is a derivative of Riboflavin (vitamin B2) which is an essential nutrient for animals. Riboflavin phosphate can be used for the research of progressive keratoconus, corneal ectasia and irregular astigmatism. Riboflavine phosphate is a very effective NAD+-recycling agent.
    Riboflavin phosphate
  • HY-100805R
    D-Glutamic acid (Standard)
    D-Glutamic acid (Standard) is the analytical standard of D-Glutamic acid. This product is intended for research and analytical applications. D-glutamic acid, an enantiomer of L- glutamic acid, is widely used in pharmaceuticals and foods.
    D-Glutamic acid (Standard)
  • HY-113005S
    Glutarylcarnitine-d9 chloride
    Glutarylcarnitine-d9 (chloride) is the deuterium labeled Glutarylcarnitine chloride. Glutarylcarnitine is the diagnostic metabolite for malonic aciduria and glutaric aciduria type I monitored in most tandem mass spectrometry newborn screening programmes.
    Glutarylcarnitine-d<sub>9</sub> chloride
  • HY-118090A
    D-γ-Glutamyl-D-glutamic acid
    		98.85%
    D-γ-Glutamyl-D-glutamic acid is a poly(γ-glutamic acid) of clusters of D- and D-glutamic acid repeating units in a linear chain.
    D-γ-Glutamyl-D-glutamic acid
  • HY-P3190
    Arginase, Microorganism (immobilized)
    Arginase, Microorganism immobilized (L-Arginine amidinase) is an enzyme of the urea cycle. Arginase catalyzes the hydrolysis of L-arginine to L-ornithine and urea.
    Arginase, Microorganism (immobilized)
  • HY-14520A
    (6S)-Tetrahydrofolic acid
    (6S)-Tetrahydrofolic acid is 1000-fold more active than the (6R) form at promoting the binding of fluorodeoxyuridylate to thymidylate synthase and 600-fold more active as a growth factor of P. cerevisiae. (6S)-Tetrahydrofolic acid also has a low affinity and high dissociation rate for folate-binding protein.
    (6S)-Tetrahydrofolic acid
  • HY-121962
    neo-Inositol
    		≥98.0%
    neo-Inositol, a stereoisomer of inositol, has been isolated from calf brain.
    neo-Inositol
  • HY-W095697
    N-Acetylhistidine
    N-Acetylhistidine is a histidine derivative that is the acetylated enzyme intermediate in the N-acetyltransferase reaction.
    N-Acetylhistidine
  • HY-103332S
    N-Arachidonylglycine-d8
    		98.1%
    N-Arachidonylglycine-d8 is a deuterated labeled N-Arachidonylglycine. N-Arachidonylglycine (NA-Gly), a carboxylic analog of the endocannabinoid anandamide (AEA), is a GPR18 agonist (EC50 = 44.5 nM). Unlike AEA, N-Arachidonylglycine has no activity at either CB1 or CB2 receptors. N-Arachidonylglycine inhibits GLYT2 (IC50 = 5.1 μM). N-Arachidonylglycine also is an effective activator of endometrial cell migration.
    N-Arachidonylglycine-d<sub>8</sub>
  • HY-113437
    1,2-Dipalmitoyl-sn-glycerol 3-phosphate
    1,2-Dipalmitoyl-sn-glycerol 3-phosphate (compound 3-F7) is a phosphatidic acid and a human endogenous metabolite.
    1,2-Dipalmitoyl-sn-glycerol 3-phosphate
  • HY-106947
    SY-640
    		99.77%
    SY-640 is an Acetamide derivative and has potent hepatoprotective effect. SY-640 reduces Propionibacterium acnes and Lipopolysaccharide-induced liver injury in mice.
    SY-640
  • HY-120954
    14,15-EE-5(Z)-E
    		≥99.0%
    14,15-EE-5(Z)-E is a structural analogue of 14, 15-epoxide dicartrienoic acid (14,15-EET). 14,15-EE-5(Z)-E antagonizes the relaxation of vascular smooth muscle induced by EET.
    14,15-EE-5(Z)-E
  • HY-B0528AS
    Octopamine-d4 hydrochloride
    		98.28%
    Octopamine-d4 (hydrochloride) is the deuterium labeled Octopamine hydrochloride. Octopamine ((±)-p-Octopamine) hydrochloride, a biogenic monoamine structurally related to noradrenaline, acts as a neurohormone, a neuromodulator and a neurotransmitter in invertebrates. Octopamine hydrochloride can stimulate alpha2-adrenoceptors (ARs) in Chinese hamster ovary cells transfected with human alpha2-ARs. Octopamine hydrochloride increased glycogenolysis, glycolysis, oxygen uptake, gluconeogenesis and the portal perfusion pressure.
    Octopamine-d<sub>4</sub> hydrochloride
  • HY-125919
    Vulpinic acid
    		99.62%
    Vulpinic acid, a lichen metabolite, decreases H2O2-induced ROS production, oxidative stress and oxidative stress-related damages in human umbilical vein endothelial cells (HUVEC). Vulpinic acid is active against staphylococci, enterococci, and anaerobic bacteria.Vulpinic acid has the potential for atherosclerosis research.
    Vulpinic acid
Cat. No. Product Name / Synonyms Application Reactivity