2. Signaling Pathways
  3. Metabolic Enzyme/Protease
  4. Endogenous Metabolite

Endogenous Metabolite

Endogenous Metabolite

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Metabolite results when a drug is metabolized into a modified form which continues to produce effects. A metabolome in a given body fluid is influenced by endogenous factors such as age, sex, body composition and genetics as well as underlying pathologies.The levels of the enormous array of unique small-molecule metabolites are usually kept tightly regulated by the activity of a very large array of enzymes and transporters responsible for the production, transformation, degradation, and compartmentalization of these small molecules.The levels of the endogenous small molecules present in the brain are normally tightly regulated.

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-111054A
    N-methyl-N-dithiocarboxyglucamine sodium
    		98.60%
    N-methyl-N-dithiocarboxyglucamine (MDCG) sodium mobilizes and promotes excretion of metallothionein-bound 109Cd in mouse model. N-methyl-N-dithiocarboxyglucamine significantly lowers the Cd content of both the liver and kidney, which is organs most susceptible to Cd-induced toxicity.
    N-methyl-N-dithiocarboxyglucamine sodium
  • HY-113225S3
    Guanosine triphosphate-15N5 dilithium
    Guanosine triphosphate-15N5 (GTP-15N5) dilithium is 15N labeled Guanosine triphosphate (HY-113225). Guanosine triphosphate is a native nucleotide. The derivatives of GTP may be used as specific inhibitors against COVID-19.
    Guanosine triphosphate-<sup>15</sup>N<sub>5</sub> dilithium
  • HY-E70035
    Glucuronokinase (AtGlcAK)
    Glucuronokinase (AtGlcAK) is a member of the GHMP-kinase. Glucuronokinase (AtGlcAK) shows unique substrate specificity for D-glucuronic acid with a Km value of 0.7 mM. Glucuronokinase (AtGlcAK) catalyzes D-glucuronic acid and ATP to produce D-glucuronic acid-1-phosphate and ADP.
    Glucuronokinase (AtGlcAK)
  • HY-W105272S
    2′-Deoxyadenosine 5′-monophosphate-13C10,15N5 disodium
    		99.8%
    2′-Deoxyadenosine 5′-monophosphate-13C10,15N5 (disodium) is the 13C and 15N labeled 2′-Deoxyadenosine 5′-monophosphate disodium. 2′-Deoxyadenosine 5′-monophosphate disodium, a nucleic acid AMP derivative, is a deoxyribonucleotide found in DNA. 2′-Deoxyadenosine 5′-monophosphate disodium can be used to study adenosine-based interactions during DNA synthesis and DNA damage.
    2′-Deoxyadenosine 5′-monophosphate-<sup>13</sup>C<sub>10</sub>,<sup>15</sup>N<sub>5</sub> disodium
  • HY-B1086
    Afalanine
    		99.88%
    Afalanine (N-Acetyl-DL-phenylalanine) is an endogenous metabolite of an endophytic fungus with antidepressant activity. Afalanine can be used in combination with antibiotics to prevent renal damage.
    Afalanine
  • HY-N0229S8
    L-Alanine-13C3
    		99.90%
    L-Alanine-13C3 is the 13C-labeled L-Alanine. L-Alanine is a non-essential amino acid, involved in sugar and acid metabolism, increases immunity, and provides energy for muscle tissue, brain, and central nervous system.
    L-Alanine-<sup>13</sup>C<sub>3</sub>
  • HY-41417R
    Octanoic acid (Standard)
    Octanoic acid (Standard) is the analytical standard of Octanoic acid. This product is intended for research and analytical applications. Octanoic acid (Caprylic acid) is an oily liquid with a slightly unpleasant rancid taste and used commercially in the production of esters used in perfumery and also in the manufacture of dyes.
    Octanoic acid (Standard)
  • HY-113144AS
    L-Hexanoylcarnitine-d3 chloride
    		99.0%
    L-Hexanoylcarnitine-d3 (chloride) is the deuterium labeled L-Hexanoylcarnitine chloride.
    L-Hexanoylcarnitine-d<sub>3</sub> chloride
  • HY-107819S
    5α-Cholestan-3β-ol-d5
    		99.18%
    5α-Cholestan-3β-ol-d5 is the deuterium labeled 5α-Cholestan-3β-ol. 5α-Cholestan-3β-ol is a derivitized steroid compound.
    5α-Cholestan-3β-ol-d<sub>5</sub>
  • HY-W337335
    1-Palmitoyl-sn-glycerol 3-phosphate sodium salt
    		99.06%
    1-Palmitoyl-sn-glycerol 3-phosphate (sodium salt) (1-P-GPA (sodium salt)) is an endogenous metabolite. 1-Palmitoyl-sn-glycerol 3-phosphate (sodium salt) can be used in the study of non-alcoholic fatty liver disease.
    1-Palmitoyl-sn-glycerol 3-phosphate sodium salt
  • HY-N5121
    Calycanthine
    		99.89%
    Calycanthine, the principal alkaloid of the order Calycanthaceae, has been isolated from a species of the genus Psychotria, and is a central nervous system toxin, causing convulsions.
    Calycanthine
  • HY-W012980S
    Isovaleric acid-d9
    		98.52%
    Isovaleric acid-d9 is the deuterium labeled Isovaleric acid. Isovaleric acid is a natural fatty acid and known to effect on neonatal death and possible Jamaican vomiting sickness in human.
    Isovaleric acid-d<sub>9</sub>
  • HY-139569
    Ebaresdax
    		99.85%
    Ebaresdax (ACP-044) can inhibit peroxynitrite oxidation derived by SIN-1 and peroxynitrite mediated Cytotoxicity with IC50s of 3.7±0.80 and 0.13±0.02 uM, respectively.
    Ebaresdax
  • HY-N0667R
    L-Asparagine (Standard)
    L-Asparagine (Standard) is the analytical standard of L-Asparagine (HY-N0667). This product is intended for research and analytical applications. L-Asparagine is an essential amino acid for leukemic cells and a substrate for L-Asparaginase. L-Asparaginase is a potent anti-leukemic enzyme that promotes asparagine (Asn) and glutamine (Gln) depletion and inhibits protein biosynthesis in lymphoblasts. Removal of L-asparagine from plasma by L-Asparaginase results in inhibition of RNA and DNA synthesis and subsequent apoptosis. L-Asparaginase has cell-killing ability in vitro and in vivo, and selectively inhibits the growth of cancer cells with low asparagine synthetase (AASNS) expression. L-Asparagine can be used as a biomarker and sensor for the study of childhood acute lymphoblastic leukemia.
    L-Asparagine (Standard)
  • HY-E70229
    Cyclooxygenase 1, sheep
    Cyclooxygenase 1, sheep (COX-1) is a 71 kDa membrane bound protein predominantly present in endoplasmic reticulum. Cyclooxygenase 1 has three domains, the epidermal growth factor (EGF) like domain, enzymatic and membrane binding domain. Cyclooxygenase 1 mediates prostaglandin synthesis and is modulated by anti-inflammatory nonsteroidal drugs.
    Cyclooxygenase 1, sheep
  • HY-N0473S7
    L-Tyrosine-1-13C
    		98.0%
    L-Tyrosine-1-13C is the 13C-labeled L-Tyrosine. L-Tyrosine is a non-essential amino acid which can inhibit citrate synthase activity in the posterior cortex.
    L-Tyrosine-1-<sup>13</sup>C
  • HY-N0680S2
    Thiamine-d4 hydrochloride
    Thiamine-d4 (hydrochloride) is deuterium labeled Thiamine (hydrochloride). Thiamine hydrochloride (Thiamine chloride hydrochloride) is an essential micronutrient needed as a cofactor for many central metabolic enzymes.
    Thiamine-d<sub>4</sub> hydrochloride
  • HY-N0326S4
    L-Methionine-1-13C
    		98.0%
    L-Methionine-1-13C is the 13C-labeled L-Methionine. L-Methionine is the L-isomer of Methionine, an essential amino acid for human development. Methionine acts as a hepatoprotectant.
    L-Methionine-1-<sup>13</sup>C
  • HY-A0143A
    Dihomo-γ-linolenic acid sodium
    		99.0%
    Dihomo-γ-linolenic acid (DGLA; all-cis-8,11,14-Eicosatrienoic acid) sodium is a 20-carbon ω-6 fatty acid, with anti-inflammatory and anti-proliferative activities. Dihomo-γ-linolenic acid (sodium) attenuates atherosclerosis in the apolipoprotein E deficient mouse model system.
    Dihomo-γ-linolenic acid sodium
  • HY-N8460A
    Cortisol sulfate sodium
    		99.79%
    Cortisol sulfate sodium (Cortisol 21-sulfate) is a metabolite of Cortisol (HY-N0583). Cortisol sulfate sodium is a specific ligand for intracellular transcortin.
    Cortisol sulfate sodium
Cat. No. Product Name / Synonyms Application Reactivity