2. Signaling Pathways
  3. Metabolic Enzyme/Protease
  4. Endogenous Metabolite

Endogenous Metabolite

Endogenous Metabolite

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Metabolite results when a drug is metabolized into a modified form which continues to produce effects. A metabolome in a given body fluid is influenced by endogenous factors such as age, sex, body composition and genetics as well as underlying pathologies.The levels of the enormous array of unique small-molecule metabolites are usually kept tightly regulated by the activity of a very large array of enzymes and transporters responsible for the production, transformation, degradation, and compartmentalization of these small molecules.The levels of the endogenous small molecules present in the brain are normally tightly regulated.

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-100354S4
    C16-Ceramide-d31
    		98.0%
    C16-Ceramide-d31 is deuterium labeled C16-Ceramide.
    C16-Ceramide-d<sub>31</sub>
  • HY-N0680S1
    Thiamine-d3 hydrochloride
    		98.92%
    Thiamine-d3 (hydrochloride) is the deuterium labeled Thiamine hydrochloride. Thiamine hydrochloride (Thiamine chloride hydrochloride) is an essential micronutrient needed as a cofactor for many central metabolic enzymes.
    Thiamine-d<sub>3</sub> hydrochloride
  • HY-19312R
    3-Methyladenine (Standard)
    3-Methyladenine (Standard) is the analytical standard of 3-Methyladenine. This product is intended for research and analytical applications. 3-Methyladenine (3-MA) is a PI3K inhibitor. 3-Methyladenine is a widely used inhibitor of autophagy via its inhibitory effect on class III PI3K.
    3-Methyladenine (Standard)
  • HY-N0893R
    Tetrahydrocurcumin (Standard)
    Tetrahydrocurcumin (Standard) is the analytical standard of Tetrahydrocurcumin. This product is intended for research and analytical applications. Tetrahydrocurcumin is a Curcuminoid found in turmeric (Curcuma longa) that is produced by the reduction of Curcumin. Tetrahydrocurcumin inhibit CYP2C9 and CYP3A4.
    Tetrahydrocurcumin (Standard)
  • HY-N0181R
    Ergosterol (Standard)
    Ergosterol (Standard) is the analytical standard of Ergosterol. This product is intended for research and analytical applications. Ergosterol is the primary sterol found in fungi, with antioxidative, anti-proliferative, and anti-inflammatory effects.
    Ergosterol (Standard)
  • HY-13710A
    Dimethindene maleate
    		99.72%
    Dimethindene maleate is a selective histamine H1 antagonist with antihistamine effects. Dimethindene maleate can be used for the research of hypersensitivity reactions.
    Dimethindene maleate
  • HY-B0332S
    Menadione-d3
    		99.08%
    Menadione-d3 is the deuterium labeled Menadione. Menadione, a synthetic naphthoquinone, can be converted to active vitamin K2 in vivo.
    Menadione-d<sub>3</sub>
  • HY-N0666B
    Aspartic acid calcium
    		98.0%
    Aspartic acid calcium (Calcium L-aspartate) is a chelate where calcium is attached to an amino acid naming L-Aspartic acid. L-Aspartic aicd calcium is an amino acid that can penetrate the blood-brain barrier. L-Aspartic aicd calcium is commonly used for preparing prodrugs to target colon and cecal tissues. L-Aspartic aicd calcium commonly used in the study of inflammatory conditions.
    Aspartic acid calcium
  • HY-113147B
    L-Palmitoylcarnitine TFA
    		98.0%
    L-Palmitoylcarnitine TFA, a long-chain acylcarnitine and a fatty acid metabolite, accumulates in the sarcolemma and deranges the membrane lipid environment during ischaemia. L-Palmitoylcarnitine TFA inhibits KATP channel activity, without affecting the single channel conductance, through interaction with Kir6.2.
    L-Palmitoylcarnitine TFA
  • HY-141793
    ATRA-biotin
    		98.43%
    ATRA-biotin (Biotin-ATRA-conjugate) is a biotin-conjugated ATRA. ATRA-biotin can be used to track ATRA in cells or a given tissue.
    ATRA-biotin
  • HY-66005S1
    Acetaminophen-d3
    		99.0%
    Acetaminophen-d3 is the deuterium labeled Acetaminophen. Acetaminophen (Paracetamol) is a selective cyclooxygenase-2 (COX-2) inhibitor with an IC50 of 25.8 μM; is a widely used antipyretic and analgesic agent. Acetaminophen is a potent hepatic N-acetyltransferase 2 (NAT2) inhibitor.
    Acetaminophen-d<sub>3</sub>
  • HY-126585S
    SAICAR-d3
    SAICAR-d3 is the deuterium labeled SAICAR. SAICAR is an intermediate of de novo purine nucleotide biosynthesis, activates pyruvate kinase isoform M2 (PKM2) in an isozyme-selective manner, with an EC50 of 0.3 mM. SAICAR stimulates PKM2 and promotes cancer cell survival in glucose-limited conditions.
    SAICAR-d<sub>3</sub>
  • HY-D0199S
    Adenosine 5′-diphosphate-15N5 disodium
    Adenosine-15N5 5′-diphosphate (disodium salt) is the 15N labeled Adenosine 5'-diphosphate disodium salt.
    Adenosine 5′-diphosphate-<sup>15</sup>N<sub>5</sub> disodium
  • HY-18646
    23,25-Dihydroxy-24-oxovitamin D3
    		99.70%
    23,25-Dihydroxy-24-oxovitamin D3 is a major metabolite of 24(R),25-Dihydroxyvitamin D3. 23,25-Dihydroxy-24-oxovitamin D3 can be used for the research of metabolic diseases.
    23,25-Dihydroxy-24-oxovitamin D3
  • HY-14608S4
    L-Glutamic acid-13C5,15N,d5
    		99.0%
    L-Glutamic acid-13C5,15N,d5 is the deuterium, 13C-, and 15-labeled L-Glutamic acid. L-Glutamic acid acts as an excitatory transmitter and an agonist at all subtypes of glutamate receptors (metabotropic, kainate, NMDA, and AMPA). L-Glutamic acid shows a direct activating effect on the release of DA from dopaminergic terminals.
    L-Glutamic acid-<sup>13</sup>C<sub>5</sub>,<sup>15</sup>N,d<sub>5</sub>
  • HY-P4605
    (Ile8)-Oxytocin
    		99.65%
    (Ile8)-Oxytocin is a neurohypophysial hormone mesotocin produced in marsupials.
    (Ile8)-Oxytocin
  • HY-B2219S9
    Stearic acid-d7
    		98.0%
    Stearic acid-d7 is the deuterium labeled Stearic acid. Stearic acid is a long chain dietary saturated fatty acid which exists in many animal and vegetable fats and oils.
    Stearic acid-d<sub>7</sub>
  • HY-N0830S18
    Palmitic acid-d
    		99.90%
    Palmitic acid-d is the deuterium labeled Palmitic acid. Palmitic acid is a long-chain saturated fatty acid commonly found in both animals and plants. PA can induce the expression of glucose-regulated protein 78 (GRP78) and CCAAT/enhancer binding protein homologous protein (CHOP) in in mouse granulosa cells.
    Palmitic acid-d
  • HY-118090A
    D-γ-Glutamyl-D-glutamic acid
    		98.85%
    D-γ-Glutamyl-D-glutamic acid is a poly(γ-glutamic acid) of clusters of D- and D-glutamic acid repeating units in a linear chain.
    D-γ-Glutamyl-D-glutamic acid
  • HY-P3190
    Arginase, Microorganism (immobilized)
    Arginase, Microorganism immobilized (L-Arginine amidinase) is an enzyme of the urea cycle. Arginase catalyzes the hydrolysis of L-arginine to L-ornithine and urea.
    Arginase, Microorganism (immobilized)
Cat. No. Product Name / Synonyms Application Reactivity