2. Signaling Pathways
  3. Metabolic Enzyme/Protease
  4. Endogenous Metabolite

Endogenous Metabolite

Endogenous Metabolite

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Metabolite results when a drug is metabolized into a modified form which continues to produce effects. A metabolome in a given body fluid is influenced by endogenous factors such as age, sex, body composition and genetics as well as underlying pathologies.The levels of the enormous array of unique small-molecule metabolites are usually kept tightly regulated by the activity of a very large array of enzymes and transporters responsible for the production, transformation, degradation, and compartmentalization of these small molecules.The levels of the endogenous small molecules present in the brain are normally tightly regulated.

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-B0421R
    Mycophenolic acid (Standard)
    Mycophenolic acid (Standard) is the analytical standard of Mycophenolic acid. This product is intended for research and analytical applications. Mycophenolic acid is a potent uncompetitive inosine monophosphate dehydrogenase (IMPDH) inhibitor with an EC50 of 0.24 μM.?Mycophenolic acid demonstrates antiviral effects against a wide range of RNA viruses including influenza. Mycophenolic acid is an immunosuppressive agent. Antiangiogenic and antitumor effects.
    Mycophenolic acid (Standard)
  • HY-N0180R
    18β-Glycyrrhetinic acid (Standard)
    18β-Glycyrrhetinic acid (Standard) is the analytical standard of 18β-Glycyrrhetinic acid. This product is intended for research and analytical applications. 18β-Glycyrrhetinic acid is the major bioactive component of Glycyrrhiza uralensis and possesses anti-ulcerative, anti-inflammatory and antiproliferative properties.
    18β-Glycyrrhetinic acid (Standard)
  • HY-I0626S2
    Cytosine-d2
    		99.69%
    Cytosine-d2 is the deuterium labeled Cytosine. Cytosine is one of the four main bases found in DNA and RNA. Cytosine modifications exhibit circadian oscillations that are involved in epigenetic diversity and aging.
    Cytosine-d<sub>2</sub>
  • HY-N0326S1
    L-Methionine-13C,d5
    		98%
    L-Methionine-13C,d5 is the 13C- and deuterium labeled L-Methionine. L-Methionine is the L-isomer of Methionine, an essential amino acid for human development. Methionine acts as a hepatoprotectant.
    L-Methionine-<sup>13</sup>C,d<sub>5</sub>
  • HY-30216AR
    Leucic acid (Standard)
    Leucic acid (Standard) is the analytical standard of Leucic acid. This product is intended for research and analytical applications. Leucic acid is an amino acid metabolite.
    Leucic acid (Standard)
  • HY-N1424R
    Glycoursodeoxycholic acid (Standard)
    Glycoursodeoxycholic acid (Standard) is the analytical standard of Glycoursodeoxycholic acid. This product is intended for research and analytical applications. Glycoursodeoxycholic acid, a acyl glycine and a bile acid-glycine conjugate, is a metabolite of ursodeoxycholic acid.
    Glycoursodeoxycholic acid (Standard)
  • HY-B1945R
    DEHP (Standard)
    DEHP (Standard) is the analytical standard of DEHP. This product is intended for research and analytical applications. DEHP (Bis(2-ethylhexyl) phthalate) is a widely used plasticizer, which has orally active. DEHP can produce a wide spectrum of toxic effects on organisms including neurotoxicity, liver toxicity, immunotoxicity, and reproductive toxicity.
    DEHP (Standard)
  • HY-Y0313S
    p-Hydroxybenzaldehyde-d4
    		99.65%
    p-Hydroxybenzaldehyde-d4 is the deuterium labeled p-Hydroxybenzaldehyde. p-Hydroxybenzaldehyde is a one of the major components in Dendrocalamus asper bamboo shoots, with antagonistic effect on GABAA receptor of the α1β2γ2S subtype at high concentrations.
    p-Hydroxybenzaldehyde-d<sub>4</sub>
  • HY-W010256S3
    D-Xylulose-13C5
    		99.9%
    D-Xylulose-13C5 is 13C labeled D-Xylulose. D-xylulose is the precursor of arabinitol.
    D-Xylulose-<sup>13</sup>C<sub>5</sub>
  • HY-W342092
    1,3,4,6-Tetrachloro-3α,6α-diphenylglycouril
    		98.0%
    1,3,4,6-Tetrachloro-3α,6α-diphenylglycouril is a chemical agent that has the property of inhibiting enzyme activity in organisms. 1,3,4,6-Tetrachloro-3α,6α-diphenylglycouril is used as a potential anti-tumor agent in compound development. 1,3,4,6-Tetrachloro-3α,6α-diphenylglycouril has the effect of regulating cell signaling pathways and can be used to study cell biology. 1,3,4,6-Tetrachloro-3α,6α-diphenylglycouril is considered to be a potent compound that can exert biological activity under specific conditions.
    1,3,4,6-Tetrachloro-3α,6α-diphenylglycouril
  • HY-113884A
    (±)-Coriolic acid
    		99.0%
    (±)13-HODE is one of the two racemic monohydroxy fatty acids resulting from the non-enzymatic oxidation of linoleic acid. It is the principle hydroxylated fatty acid in human psoriatic skin scales, with a mean concentration of 17 ng/mg.
    (±)-Coriolic acid
  • HY-W768345
    D-(+)-Trehalose-13C12
    		99.9%
    D-(+)-Trehalose-13C12 is a 13C isotope labeled version of D-(+)-Trehalose (HY-N1132). D-(+)-Trehalose,which is widespread, can be used as a food ingredient and pharmaceutical excipient.
    D-(+)-Trehalose-<sup>13</sup>C<sub>12</sub>
  • HY-112540
    Acetoacetic acid
    Acetoacetic acid is an oxidative stress inducer that affects the antioxidant enzyme system and lipoprotein metabolism. Acetoacetic acid induces oxidative stress by decreasing the mRNA expression and activity of superoxide dismutase (SOD), catalase (CAT), and glutathione peroxidase (GSH-Px), increasing MDA content, and inhibiting very low density lipoprotein (VLDL) assembly by downregulating apolipoprotein ApoB100, ApoE, and low density lipoprotein receptor (LDLR), leading to triglyceride (TG) accumulation in hepatocytes. Acetoacetic acid can be used to study metabolic diseases.
    Acetoacetic acid
  • HY-W004283R
    Pentadecanoic acid (Standard)
    α-Linolenic acid (Standard) is the analytical standard of α-Linolenic acid. This product is intended for research and analytical applications. α-Linolenic acid, isolated from Perilla frutescens, is an essential fatty acid that cannot be synthesized by humans. α-Linolenic acid can affect the process of thrombotic through the modulation of PI3K/Akt signaling. α-Linolenic acid possess the anti-arrhythmic properties and is related to cardiovascular disease and cancer.
    Pentadecanoic acid (Standard)
  • HY-137899
    Dephospho-CoA
    Dephospho-CoA is a key intermediate in the biosynthesis of coenzyme A (CoA), which is catalyzed by GTP-dependent dephospho-CoA kinase (DPCK) to generate CoA. Dephospho-CoA completes the final synthesis step of CoA through phosphorylation reaction and participates in energy metabolism and cell signaling. Dephospho-CoA can be used in research including cancer (such as regulating cell proliferation) and metabolic diseases (such as mitochondrial dysfunction).
    Dephospho-CoA
  • HY-113409R
    3-Hydroxyisovaleric acid (Standard)
    3-Hydroxyisovaleric acid (Standard) is the analytical standard of 3-Hydroxyisovaleric acid. This product is used for research and analytical applications. 3-Hydroxyisovaleric acid is a normal endogenous metabolite excreted in urine. The urinary excretion of 3-Hydroxyisovaleric acid serves as an early and sensitive indicator of biotin deficiency.
    3-Hydroxyisovaleric acid (Standard)
  • HY-W013175S2
    Uridine 5'-monophosphate-13C9,15N2 disodium
    		99.0%
    Uridine 5'-monophosphate-13C9,15N2 disodium is the 13C and 15N labeled Uridine 5'-monophosphate disodium salt (HY-W013175). Uridine 5'-monophosphate (5'-Uridylic acid) disodium salt is an orally active mitochondrial ATP-dependent potassium channel activator that has a protective effect on the heart. Uridine 5'-monophosphate disodium salt can promote the synthesis of CDP-choline and induce apoptosis in intestinal epithelial cells, which is beneficial for gut development and reduces diarrhea.
    Uridine 5'-monophosphate-<sup>13</sup>C<sub>9</sub>,<sup>15</sup>N<sub>2</sub> disodium
  • HY-B1654R
    Flavin adenine dinucleotide (Standard)
    Flavin adenine dinucleotide (Standard) is the analytical standard of Flavin adenine dinucleotide. This product is intended for research and analytical applications. Flavin adenine dinucleotide (FAD) is a redox cofactor, more specifically a prosthetic group of a protein, involved in several important enzymatic reactions in metabolism.
    Flavin adenine dinucleotide (Standard)
  • HY-17363R
    Dimethyl fumarate (Standard)
    Dimethyl fumarate (Standard) is the analytical standard of Dimethyl fumarate. This product is intended for research and analytical applications. Dimethyl fumarate (DMF) is an orally active and brain-penetrant Nrf2 activator and induces upregulation of antioxidant gene expression. Dimethyl fumarate induces necroptosis in colon cancer cells through GSH depletion/ROS increase/MAPKs activation pathway, and also induces cell autophagy. Dimethyl fumarate can be used for multiple sclerosis research.
    Dimethyl fumarate (Standard)
  • HY-W015891
    ε-Caprolactone
    		99.99%
    ε-Caprolactone is a lactone compound that can be isolated from the Arctic thorn.
    ε-Caprolactone
Cat. No. Product Name / Synonyms Application Reactivity