2. Signaling Pathways
  3. Metabolic Enzyme/Protease
  4. Endogenous Metabolite

Endogenous Metabolite

Endogenous Metabolite

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Metabolite results when a drug is metabolized into a modified form which continues to produce effects. A metabolome in a given body fluid is influenced by endogenous factors such as age, sex, body composition and genetics as well as underlying pathologies.The levels of the enormous array of unique small-molecule metabolites are usually kept tightly regulated by the activity of a very large array of enzymes and transporters responsible for the production, transformation, degradation, and compartmentalization of these small molecules.The levels of the endogenous small molecules present in the brain are normally tightly regulated.

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-Y0760
    3-Methoxybenzoic acid
    		99.61%
    3-Methoxybenzoic acid can form complexes with metals, such as europium (III) and gadolinium (III). 3-Methoxybenzoic acid can be metabolized by anaerobic bacteria through O-demethylation mechanism.
    3-Methoxybenzoic acid
  • HY-P2918
    Phosphoglucose Isomerase, Rabbit muscle
    Phosphoglucose Isomerase, Rabbit muscle (GPI), i.e., phosphoglucose isomerase/phosphoglucoisomerase (PGI) or phosphohexose isomerase (PHI), is often used in biochemical studies. Glucose 6-phosphate isomeras is a highly conserved glycolytic and dimeric enzyme. Glucose 6-phosphate isomeras catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
    Phosphoglucose Isomerase, Rabbit muscle
  • HY-101036
    Choline bitartrate
    		98.0%
    Choline bitartrate is a vitamin-like essential nutrient, can affect diseases such as liver disease, atherosclerosis and neurological disorders. Choline bitartrate is a precursor for the neurotransmitter acetylcholine, as a methyl donor in various metabolic processes, and in lipid metabolism.
    Choline bitartrate
  • HY-E70308
    Glucose isomerase (immobilized)
    Glucose isomerase (immobilized) is a glucose isomerase that catalyzes the reversible isomerization of D-glucose and D-xylose into D-fructose and D-xylulose, respectively. Glucose isomerase (immobilized) is thermally stable and can be used to produce fructose syrup at high temperatures above 90°C. Glucose isomerase (immobilized) is widely distributed in prokaryotes.
    Glucose isomerase (immobilized)
  • HY-W040971
    Creosol
    		99.82%
    Creosol (2-Methoxy-4-methylphenol) is an endogenous metabolite that acts as an important chemical intermediate and potential biofuel mainly derived from lignocellulosic biomass. Creosol is blood brain barrier penetrable.
    Creosol
  • HY-113094
    Paullinic acid
    		98.0%
    Paullinic acid is a long-chain fatty acid that has been detected in multiple biofluids, such as blood and urine.
    Paullinic acid
  • HY-121305A
    L-Ribulose
    L-Ribulose, an isomer of L-ribose, is an important precursor for other rare sugars and L-nucleoside analogue synthesis.
    L-Ribulose
  • HY-108568S
    15-Deoxy-Δ-12,14-prostaglandin J2-d4
    		98.10%
    15-Deoxy-Δ-12,14-prostaglandin J2-d4 is the deuterium labeled 15-Deoxy-Δ-12,14-prostaglandin J2. 15-Deoxy-Δ-12,14-prostaglandin J2 (15d-PGJ2) is a cyclopentenone prostaglandin and a metabolite of PGD2. 15-Deoxy-Δ-12,14-prostaglandin J2 is a selective PPARγ (EC50 of 2 μM) and a covalent PPARδ agonist. 15-Deoxy-Δ-12,14-prostaglandin J2 promotes efficient differentiation of C3H10T1/2 fibroblasts to adipocytes with an EC50 of 7 μM.
    15-Deoxy-Δ-12,14-prostaglandin J2-d<sub>4</sub>
  • HY-N0593R
    Deoxycholic acid (Standard)
    Deoxycholic acid (Standard) is the analytical standard of Deoxycholic acid. This product is intended for research and analytical applications. Deoxycholic acid (cholanoic acid), a bile acid, is a by-product of intestinal metabolism, that activates the G protein-coupled bile acid receptorTGR5.
    Deoxycholic acid (Standard)
  • HY-W041895S1
    DL-Glutamic acid-d3
    		98.0%
    DL-Glutamic acid-d3 is the deuterium labeled DL-Glutamic acid. DL-Glutamic acid is the conjugate acid of Glutamic acid, which acts as a fundamental metabolite. Comparing with the second phase of polymorphs α and β L-Glutamic acid, DL-Glutamic acid presents better stability.
    DL-Glutamic acid-d<sub>3</sub>
  • HY-113151
    18-Oxocortisol
    		99.05%
    18-Oxocortisol is a derivative of cortisol that is produced by aldosterone synthase (CYP11B2). 18-Oxocortisol is a naturally occurring mineralocorticoid agonist. 18-Oxocortisol is a biomarker in adrenal vein sampling.
    18-Oxocortisol
  • HY-14608S6
    L-Glutamic acid-5-13C
    		98.0%
    L-Glutamic acid-5-13C is the 13C-labeled L-Glutamic acid. L-Glutamic acid acts as an excitatory transmitter and an agonist at all subtypes of glutamate receptors (metabotropic, kainate, NMDA, and AMPA). L-Glutamic acid shows a direct activating effect on the release of DA from dopaminergic terminals.
    L-Glutamic acid-5-<sup>13</sup>C
  • HY-W017018S5
    L-Ornithine-15N2 hydrochloride
    		98.90%
    L-Ornithine-15N2 (hydrochloride) is the 15N-labeled L-Ornithine hydrochloride. L-Ornithine hydrochloride is a free amino acid that plays a central role in the urea cycle and is also important for the disposal of excess nitrogen.
    L-Ornithine-<sup>15</sup>N<sub>2</sub> hydrochloride
  • HY-N0229S9
    L-Alanine-13C2
    		99.97%
    L-Alanine-13C2 is the 13C-labeled L-Alanine. L-Alanine is a non-essential amino acid, involved in sugar and acid metabolism, increases immunity, and provides energy for muscle tissue, brain, and central nervous system.
    L-Alanine-<sup>13</sup>C<sub>2</sub>
  • HY-N2854
    α-Viniferin
    		99.43%
    α-Viniferin is an anti-inflammatory compound from Caragana chamlagu root.
    α-Viniferin
  • HY-N0326S8
    L-Methionine-d8
    		98.0%
    L-Methionine-d8 is the deuterium labeled L-Methionine. L-Methionine is the L-isomer of Methionine, an essential amino acid for human development. Methionine acts as a hepatoprotectant.
    L-Methionine-d<sub>8</sub>
  • HY-W008253S1
    5-Hydroxyindole-3-acetic acid-d6
    		99.0%
    5-Hydroxyindole-3-acetic acid-d6 is the deuterium labeled 5-Hydroxyindole-3-acetic acid. 5-Hydroxyindole-3-acetic acid is the main metabolite of serotonin or metanephrines, which can be used as a biomarker of neuroendocrine tumors.
    5-Hydroxyindole-3-acetic acid-d<sub>6</sub>
  • HY-W038287
    2-Methylbenzoxazole
    		99.95%
    2-Methylbenzoxazole is an endogenous metabolite.
    2-Methylbenzoxazole
  • HY-A0181S
    Adenosine monophosphate-13C10,15N5 dilithium
    		≥99.0%
    Adenosine monophosphate-13C10,15N5(AMP-13C10,15N5) is the 13C-labeled and 15N-labeled Adenosine monophosphate (HY-A0181). Adenosine monophosphate is an adenosine A1 receptor agonist. Adenosine monophosphate has significant antiviral activity against HSV-1 and HSV-2. Adenosine monophosphate is a key cellular metabolite regulating energy homeostasis and signal transduction.
    Adenosine monophosphate-<sup>13</sup>C<sub>10</sub>,<sup>15</sup>N<sub>5</sub> dilithium
  • HY-69014
    2-O-Methylcytosine
    		99.87%
    2-O-Methylcytosine, an O-alkylated analogue a DNA adduct, is the damaged nucleobase.
    2-O-Methylcytosine
Cat. No. Product Name / Synonyms Application Reactivity