2. Signaling Pathways
  3. Anti-infection
  4. HBV
  5. HBV Modulator

HBV Modulator

HBV Modulators (3):

Cat. No. Product Name Effect Purity
  • HY-144320
    HBV-IN-17
    		Modulator
    HBV-IN-17 (compound 8) is a potent HBV capsid assembly modulator with an EC50 of 511 nM.
  • HY-174819
    VNRX-9945
    		Modulator
    VNRX-9945 is a potent, broadly and orally active HBV CAM (capsid assembly modulator) with an EC50 of 2.6 nM. VNRX-9945 exhibits excellent and broad antiviral activity against multiple HBV genotypes in vitro, along with favorable pharmacokinetic profiles across multiple species. VNRX-9945 demonstrates robust antiviral efficacy in the adeno-associated virus mice models of HBV (AAV-HBV) infection.
  • HY-144322
    HBV-IN-18
    		Modulator
    HBV-IN-18 (Compound 3) is an HBV capsid assembly modulator (CpAM) with an EC50 of 2790 nM.