Rosuvastatin-d₆ sodium

Cat. No.: HY-17504BS1 Purity: 98.60%: Data Sheet
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Rosuvastatin-d₆ sodium is deuterium labeled Rosuvastatin sodium (HY-17504B). Rosuvastatin Sodium is a competitive HMG-CoA reductase (HMGCR) inhibitor, with an IC₅₀ of 11 nM. Rosuvastatin Sodium potently blocks hERG current with an IC₅₀ of 195 nM. Rosuvastatin Sodium reduces the expression of the mature hERG and the interaction of heat shock protein 70 (Hsp70) with the hERG protein. Rosuvastatin Sodium effectively lowers low-density lipoprotein (LDL) cholesterol, triglycerides, and C-reactive protein levels.

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Rosuvastatin-d₆ sodium Chemical Structure

CAS No. : 2070009-41-3

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1 mg	Get quote	Estimated Time of Arrival: December 31
5 mg	Get quote	Estimated Time of Arrival: December 31
500 μg	In-stock	Estimated Time of Arrival: December 31

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Description	Rosuvastatin-d₆ sodium is deuterium labeled Rosuvastatin sodium (HY-17504B). Rosuvastatin Sodium is a competitive HMG-CoA reductase (HMGCR) inhibitor, with an IC₅₀ of 11 nM. Rosuvastatin Sodium potently blocks hERG current with an IC₅₀ of 195 nM. Rosuvastatin Sodium reduces the expression of the mature hERG and the interaction of heat shock protein 70 (Hsp70) with the hERG protein. Rosuvastatin Sodium effectively lowers low-density lipoprotein (LDL) cholesterol, triglycerides, and C-reactive protein levels.
Application	1. This compound can be used as a tracer. 2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
In Vitro	Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs. MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. Rosuvastatin-d₆ sodium Related Antibodies
Molecular Weight	509.56
Formula	C₂₂H₂₁D₆FN₃NaO₆S
CAS No.	2070009-41-3
Unlabeled CAS	147098-18-8
Appearance	Solid
Color	White to off-white
SMILES	O=C(O[Na])C[C@H](O)C[C@H](O)/C=C/C1=C(C(C([2H])([2H])[2H])C([2H])([2H])[2H])N=C(N(C)S(C)(=O)=O)N=C1C2=CC=C(C=C2)F
Shipping	Room temperature in continental US; may vary elsewhere.
Storage	-20°C, sealed storage, away from moisture *In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Purity & Documentation	Purity: 98.6% Select Batch: Data Sheet (245 KB) SDS (392 KB) COA (252 KB) Handling Instructions (2659 KB)