2. Inflammation/Immunology

Inflammation/Immunology

Inflammation/Immunology

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The diseases caused by disorders of the immune system fall into two broad categories: immunodeficiency and autoimmunity. Immunotherapy is also often used in the immunosuppressed (such as HIV patients) and people suffering from other immune deficiencies or autoimmune diseases. This includes regulating factors such as IL-2, IL-10, IFN-α. Infection with HIV is characterized not only by development of profound immunodeficiency but also by sustained inflammation and immune activation. Chronic inflammation as a critical driver of immune dysfunction, premature appearance of aging-related diseases, and immune deficiency.

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-P1789
    CTTHWGFTLC, CYCLIC 244082-19-7 98%
    CTTHWGFTLC, CYCLIC is a cyclic peptide inhibitor for matrix metalloproteinases MMP-2 and MMP-9. The IC50 value for MMP-9 is ~8 μM.
    CTTHWGFTLC, CYCLIC
  • HY-P1793
    α-Casein (90-95) 83471-50-5 99.51%
    α-Casein (90-95) is a partial agonist of opioid receptors and a copper ion ligand, with opioid activity. α-Casein (90-95) inhibits the secretion of β-hexosaminidase by rat peritoneal mast cells (PMC) with IC50= 0.1 μM. α-Casein (90-95) inhibits the proliferation of prostate cancer cells LNCaP, DU145, and PC3 with IC50 of 0.94 nM, 137 nM, and 6.92 nM, respectively. α-Casein (90-95) activates Gi-like proteins through a membrane-assisted, receptor-independent pathway, or reversibly binds to opioid receptors, inducing intracellular calcium release and conformational changes, and exerts the activity of promoting mast cell secretion and inhibiting tumor cell proliferation. α-Casein (90-95) can be used in the study of the mechanisms of allergic diseases and prostate cancer.
    α-Casein (90-95)
  • HY-P1803
    Protein Kinase C Peptide Substrate 120253-69-2 98%
    Protein Kinase C Peptide Substrate is targeted to a specific cellular compartment in a manner dependent on second messengers and on specific adapter proteins in response to extracellular signals that activate G-protein-coupled receptors, tyrosine kinase receptors, or tyrosine kinase-coupled receptors. Protein Kinase C Peptide Substrate then regulates various physiological functions including the activation of nervous, endocrine, exocrine, inflammatory, and immune systems.
    Protein Kinase C Peptide Substrate
  • HY-P1807
    Mast Cell Degranulating Peptide HR-2 80388-04-1 98%
    Mast Cell Degranulating Peptide HR-2, a 14-membered linear peptide isolated from the venom of the giant hornet Vespa orientalis, is capable of degranulating mast cells and thus initiating histamine release.
    Mast Cell Degranulating Peptide HR-2
  • HY-P1824
    C-Reactive Protein (CRP) (201-206) 130348-99-1 98%
    C-Reactive Protein (CRP) 201-206 is the 201-206 fragment of C-Reactive Protein. C-Reactive Protein (CRP), the prototypic marker of inflammation, is a cardiovascular risk marker and may promote atherogenesis.
    C-Reactive Protein (CRP) (201-206)
  • HY-P1825
    TNF-α (10-36), human 144796-70-3 98%
    TNF-α (10-36), human is a peptide of human TNF-α.
    TNF-α (10-36), human
  • HY-P1832
    PTD-p65-P1 Peptide 98%
    PTD-p65-P1 Peptide is a potent, selective nuclear transcription factor NF-κB inhibitor and derives from the p65 subunit of NF-κB amino acid residues 271-282, which selectively inhibits NF-κB activation induced by various inflammatory stimulation, down-regulate NF-κB-mediated gene expression and up-regulate apoptosis.
    PTD-p65-P1 Peptide
  • HY-P1834
    MARCKS Peptide(151-175), Phosphorylated 98%
    MARCKS Peptide(151-175), Phosphorylated is a phosphorylated peptide corresponding to the basic effector domain of myristoylated alanine-rich protein kinase C substrate protein (MARCKS). Phosphorylation of MARCKS Peptide (151-175) reverses its inhibition of phospholipase C (PLC)-catalyzed hydrolysis of phosphatidylinositol 4,5-bisphosphate (PIP2).
    MARCKS Peptide(151-175), Phosphorylated
  • HY-P1835
    CEF8, Influenza Virus NP (383-391) 142479-13-8 98%
    CEF8, Influenza Virus NP (383-391), an influenza A virus nucleoprotein containing residues 383 to 391, is the most important HLA-B*2705-restricted epitope in the nucleoprotein of influenza A viruses and is associated with escape from cytotoxic T lymphocytes-mediated immunity.
    CEF8, Influenza Virus NP (383-391)
  • HY-P1836
    C-Reactive Protein (CRP) (77-82) 130349-01-8 98%
    C-Reactive Protein (CRP) 77-82 is the 77-82 fragment of C-Reactive Protein. C-Reactive Protein (CRP), the prototypic marker of inflammation, is a cardiovascular risk marker and may promote atherogenesis.
    C-Reactive Protein (CRP) (77-82)
  • HY-P1861
    Interphotoreceptor Retinoid Binding Protein Fragment (IRBP) 211426-18-5 98%
    Interphotoreceptor Retinoid Binding Protein Fragment (IRBP), a 20-residue peptide and a major pathogenic epitope, is present in the first homologous repeat of the interphotoreceptor retinoid binding protein peptide (IRBP 161–180), which can induce posterior uveitis (EAU).
    Interphotoreceptor Retinoid Binding Protein Fragment (IRBP)
  • HY-P1870
    OVA sequence (323-336) 92915-80-5 98%
    OVA sequence (323-336) is a cognate helper T-lymphocyte peptide that is employed to enhance CTL epitope immunogenicity.
    OVA sequence (323-336)
  • HY-P1882
    Type A Allatostatin I 123209-95-0 98%
    Type A Allatostatin I is a tridecapeptide. Allatostatins are pleiotropic neuropeptides for inhibition of juvenile hormone synthesis in insects.
    Type A Allatostatin I
  • HY-P1897
    Fibronectin Active Fragment Control 97461-84-2 98%
    Fibronectin Active Fragment Control is an active peptide fragment of fibronectin. Fibronectin is a glycoprotein interacting with integrins.
    Fibronectin Active Fragment Control
  • HY-P1916
    FliC, Serotype a (427-441), S.paratyphi A 857678-38-7 98%
    FliC, Serotype a (427-441), S.paratyphi A is amino acids 427 to 441 fragment belongs to the FliC, serotype a of the S. FliC epitope.
    FliC, Serotype a (427-441), S.paratyphi A
  • HY-P1917
    Uty HY Peptide (246-254) 261172-28-5 98%
    Uty HY Peptide (246-254), derived from the ubiquitously transcribed tetratricopeptide repeat gene on the Y chromosome (UTY) protein as an H-Y epitope, H-YDb, is a male-specific transplantation antigen H-Y.
    Uty HY Peptide (246-254)
  • HY-P1920
    CEF19, Epstein-Barr Virus latent NA-3A (458-466) 157876-41-0 98%
    CEF19, Epstein-Barr Virus latent NA-3A (458-466) is a single peptide epitope, YPLHEQHGM, representing residues 458-466 of the type 1 Epstein-Barr Virus (EBV) nuclear antigen 3A protein (B95.8 strain). CEF19, Epstein-Barr Virus latent NA-3A (458-466) can significantly affect cytotoxic T-lymphocyte (CTL) recognition.
    CEF19, Epstein-Barr Virus latent NA-3A (458-466)
  • HY-P1930
    Risuteganib 1307293-62-4 98%
    Risuteganib is a synthetic RGD (arginyl-glycyl-aspartic acid)-class peptide. Risuteganib is an anti-integrin that downregulates oxidative stress and restores homeostasis, and targets three integrin receptors that are implicated in dry age-related macular degeneration (AMD) in order to restore homeostasis in the retina.
    Risuteganib
  • HY-P1931
    Antiflammin-1 118850-71-8 98%
    Antiflammin-1 is an anti-inflammatory peptide 1 (MQMKKVLDS). Antiflammin-1 is a derivative of uteroglobin. Antiflammin-1 has anti-inflammatory and antifibrotic actions in bleomycin (HY-108345)-induced lung injury.
    Antiflammin-1
  • HY-P1948
    Thioredoxin reductase peptide 950890-23-0 98%
    Thioredoxin reductase peptide corresponds to residues 53–67 in thioredoxin reductase (TrxR), used in thioredoxin reductase research. Thioredoxin reductase acts as a reductant of disulfide-containing proteins and plays crucial role in cellular antioxidant defense.
    Thioredoxin reductase peptide
Cat. No. Product Name / Synonyms Application Reactivity