2. Infection

Infection

Infection

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Infection is a pathophysiological process that involves the invasion and colonization of a living organism (host) by disease-causing infectious agents, the reaction of host tissues to these agents and the toxins they produce, and the transmission of infectious agents to other hosts. Common infectious agents include viruses, viroids, prions, bacteria, nematodes, arthropods, and other macroparasites such as tapeworms. Hosts can fight infections using their immune system. Mammals often engage both innate and adaptive immune systems to eliminate infectious agents or inhibit their growth and transmission. When infection occurs, anti-infective drugs can suppress the infection. Several broad types of anti-infective drugs exist, depending on the type of organism targeted; they include antibacterial (antibiotic), antiviral, antifungal and antiparasitic agents.

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-Y0403
    3-Chlorobenzoic acid 535-80-8 99.71%
    3-Chlorobenzoic acid (m-Chlorobenzoic acid) is the only carbon source for the bacterium.
    3-Chlorobenzoic acid
  • HY-Y1049
    2-Amino-6-bromopyridine 19798-81-3
    2-Amino-6-bromopyridine (compound 7) is a PqsR ligand with a Kd values of 6.8 μM in the SPR assay. 2-Amino-6-bromopyridine shows a weak antagonistic activity.
    2-Amino-6-bromopyridine
  • HY-119749
    Diazaborine 22959-81-5 98.01%
    Diazaborine is an inhibitor for enoyl-acyl carrier protein (enoyl ACP) in an NAD+-dependent manner. Diazaborine exhibits antibacterial activity, MIC for E. coli and K. pneumoniae is 25 and 3.12 μg/mL.
    Diazaborine
  • HY-131583
    MP265 544-47-8 99.50%
    MP265 (4-Chlorobenzyl carbamimidothioate hydrochloride) is a structural analogue of A22 but is less toxic. MP265 is a MreB inhibitor.
    MP265
  • HY-148077
    Phosphoglycolohydroxamic acid 51528-59-7 ≥98.0%
    Phosphoglycolohydroxamic acid is a potent aldolase and triose-phosphate isomerase inhibitor. Phosphoglycolohydroxamic acid can be used in the research of antibacterial and antifungal area.
    Phosphoglycolohydroxamic acid
  • HY-156215
    NCI-B16 802835-01-4 98%
    NCI-B16 is a small molecule RNA binder and inhibits HCV viral replication.
    NCI-B16
  • HY-15971A
    AMD 3465 185991-24-6 99.59%
    AMD 3465 (GENZ-644494) is a potent antagonist of CXCR4, inhibits binding of 12G5 mAb and CXCL12AF647 to CXCR4, with IC50s of 0.75 nM and 18 nM in SupT1 cells; AMD 3465 also potently inhibits the replication of X4 HIV strains (IC50: 1-10 nM), but has no effect on CCR5-using (R5) viruses.
    AMD 3465
  • HY-22055B
    AN-12-H5 intermediate-1 254882-14-9 ≥98.0%
    AN-12-H5 intermediate-1 ((2S,4S)-1-tert-butyl 2-methyl-4-hydroxypiperidine-1,2-dicarboxylate) is an intermediate of the viral inhibitor AN-12-H5 (HY-120900) and can be used to synthesize Antibody-Drug Conjugates (ADCs).
    AN-12-H5 intermediate-1
  • HY-B0905A
    Tilmicosin phosphate 137330-13-3 ≥98.0%
    Tilmicosin (LY-177370) phosphate is an orally active calcium channel antagonist and macrolide antibiotic with antimicrobial activity. Tilmicosin phosphate mainly acts on the 50S subunit of bacterial ribosomes, inhibiting protein synthesis. Tilmicosin phosphate is effective in the treatment of respiratory diseases in livestock such as cattle, sheep and pigs. In addition, Tilmicosin phosphate has immunomodulatory and anti-inflammatory effects.
    Tilmicosin phosphate
  • HY-128554S
    N-Desethyl amodiaquine-d5 1173023-19-2 ≥98.0%
    N-Desethyl amodiaquine-d5 is the deuterium labeled N-Desethyl amodiaquine. N-Desethyl amodiaquine is the major biologically active metabolite of Amodiaquine. N-Desethyl amodiaquine is an antiparasitic agent. IC50 values for strains V1/S and 3D7 are 97 nM and 25 nM, respectively.
    N-Desethyl amodiaquine-d5
  • HY-N0097S4
    Guanosine-13C10
    Guanosine-13C10 is the 13C labeled Guanosine (HY-N0097). Guanosine is a purine nucleoside comprising guanine attached to a ribose (ribofuranose) ring via a β-N9-glycosidic bond. Guanosine possesses anti-HSV activity.
    Guanosine-13C10
  • HY-W009722
    Sodium diethylcarbamodithioate trihydrate 20624-25-3 ≥98.0%
    Sodium diethylcarbamodithioate (Ditiocarb sodium) trihydrate is a copper reagent. The reaction with Cu2+ solution resulted in the formation of a complex, which increased the copper displacement precipitation rate. Sodium diethylcarbamodithioate trihydrate can reduce HIV infection and can be used in adjuvant immune research of high-risk breast cancer.
    Sodium diethylcarbamodithioate trihydrate
  • HY-W015461
    2-Aminooctanoic acid 644-90-6 ≥98.0%
    2-Aminooctanoic acid (DL-α-Aminocaprylic acid) is a fatty acid with an amino functional group that can be directly coupled at both the C-terminal and N-terminal with antimicrobial peptides (AMP) derived from lactoferrin B to enhance antibacterial activity.
    2-Aminooctanoic acid
  • HY-W017982
    Kathon 886MW 55965-84-9
    Kathon 886MW is an efficient broad-spectrum biocide suitable for various metalworking fluids.
    Kathon 886MW
  • HY-W018667
    3-Acetylindole 703-80-0
    3-Acetylindole can be used as a precursor for synthesis of antiviral agents.
    3-Acetylindole
  • HY-W068682
    1-Hydroxyphenazine 528-71-2 99.80%
    1-Hydroxyphenazine (Hemipyocyanine; 1-Phenazinol; Hemi-pyocyanin) is an inhibitor for α-Amylase with an IC50 of 3.1 μg/mL. 1-Hydroxyphenazine exhibits anticancer and anti-inflammatory activity against cells A549, 1321N1 and RAW264.7, antifungal and antibacterial activity against strains Candida albicans, Aspergillus fumigatus, Escherichia coli and Xanthomonas campestris.
    1-Hydroxyphenazine
  • HY-W251687
    2'-Deoxy-2'-fluoroarabinoadenosine 20227-41-2 99.92%
    2'-Deoxy-2'-fluoroarabinoadenosine is a nucleoside analogue, which exhibits anticancer activity against human immunodeficiency virus (HIV).
    2'-Deoxy-2'-fluoroarabinoadenosine
  • HY-B1210
    Pipemidic acid 51940-44-4 ≥98.0%
    Pipemidic acid , a derivative of Piromidic acid, is an antibacterial agent. Pipemidic acid inhibits DNA gyrase. Pipemidic acid is active against gram-negative bacteria including Pseudomonas aeruginosa as well as some gram-positive bacteria. Pipemidic acid can be used for the research of intestinal, urinary, and biliary tract infections.
    Pipemidic acid
  • HY-132280
    Tirilazad 110101-66-1 98.11%
    Tirilazad is a nonglucocorticoid, 21-aminosteroid that inhibits lipid peroxidation. Tirilazad can attenuate brain or spinal cord injury caused by trauma, stroke, ischemia and reperfusion injury. Tirilazad has antiviral activities against nCoV. Tirilazad is neuroprotective for ischaemic stroke, can be used for subarachnoid hemorrhage research.
    Tirilazad
  • HY-14775
    Nesbuvir 691852-58-1 99.21%
    Nesbuvir is a nonnucleoside inhibitor of the hepatitis C virus (HCV) nonstructural protein 5B (NS5B) polymerase.
    Nesbuvir
Cat. No. Product Name / Synonyms Application Reactivity