2. Infection

Infection

Infection

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Infection is a pathophysiological process that involves the invasion and colonization of a living organism (host) by disease-causing infectious agents, the reaction of host tissues to these agents and the toxins they produce, and the transmission of infectious agents to other hosts. Common infectious agents include viruses, viroids, prions, bacteria, nematodes, arthropods, and other macroparasites such as tapeworms. Hosts can fight infections using their immune system. Mammals often engage both innate and adaptive immune systems to eliminate infectious agents or inhibit their growth and transmission. When infection occurs, anti-infective drugs can suppress the infection. Several broad types of anti-infective drugs exist, depending on the type of organism targeted; they include antibacterial (antibiotic), antiviral, antifungal and antiparasitic agents.

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-14881AR
    Bedaquiline fumarate (Standard) 845533-86-0
    Bedaquiline (fumarate) (Standard) is the analytical standard of Bedaquiline (fumarate). This product is intended for research and analytical applications. Bedaquiline fumarate, a diarylquinoline antibiotic that targets ATP synthase, is effective for the treatment of Mycobacterium tuberculosis infections.
    Bedaquiline fumarate (Standard)
  • HY-160791A
    Claramine TFA 3030428-57-7
    Claramine TFA is a steroidal polyamine. Claramine TFA can regulate the properties of lipid membranes and protect cells from various biological toxins, including misfolded protein oligomers and toxins derived from biological proteins.
    Claramine TFA
  • HY-40354AS
    Tofacitinib-d3 citrate 2701680-77-3 99.14%
    Tofacitinib-d3 (citrate) is deuterium labeled Tofacitinib (citrate). Tofacitinib citrate is an orally available JAK1/2/3 inhibitor with IC50s of 1, 20, and 112 nM, respectively. Tofacitinib citrate has antibacterial, antifungal and antiviral activities.
    Tofacitinib-d3 citrate
  • HY-N0610S1
    trans-Cinnamic acid-d7 343338-31-8 99.98%
    trans-Cinnamic acid-d7 is the deuterium labeled trans-Cinnamic acid. trans-Cinnamic acid is a natural antimicrobial, with minimal inhibitory concentration (MIC) of 250 μg/mL against fish pathogen A. sobria, SY-AS1.
    trans-Cinnamic acid-d7
  • HY-W010435
    Sulcatone 110-93-0 ≥98.0%
    Sulcatone (6-Methyl-5-hepten-2-one) is a plant-derived volatile organic compound with activities such as insecticidal, antifungal, and blood pressure-lowering effects. Sulcatone also serves as an insect pheromone and an endogenous metabolite, which can be found in feces. Changes in Sulcatone levels can be used for the auxiliary diagnosis of ulcerative colitis.
    Sulcatone
  • HY-W010520
    Methylisothiazolinone 2682-20-4 99.37%
    Methylothiazolinone is a bacterial and fungal inhibitor and preservative, as well as a sensitizer. Methylisothiazolinone can activate matrix metalloproteinases (MMPs) in human bronchial epithelial cells to induce apoptosis and inflammatory response. Methylisothiazolinone can promote the development of atopic dermatitis in mice by disrupting Th2/Th17 related immune responses. Methylisothiazolinone can cause mitochondrial damage in the endothelium of rat cerebral blood vessels.
    Methylisothiazolinone
  • HY-W012282
    3′-Deoxyuridine 7057-27-4
    3′-Deoxyuridine is a potential anticancer and antiviral agent. 3'-deoxyuridine inhibits bovine diarrhoea virus (BVDV) production.
    3′-Deoxyuridine
  • HY-W013168
    4-Nitrophenyl palmitate 1492-30-4 ≥98.0%
    4-Nitrophenyl palmitate (4-Nitrophenyl hexadecanoate; p-Nitrophenyl Palmitate) is a colorimetric lipase and esterase substrate. Upon enzymatic hydrolysis of 4-Nitrophenyl palmitate, 4-nitrophenol is released, which can be quantified by colorimetric detection at 410 nm as a measure of enzyme activity. 4-Nitrophenyl palmitate has been used to characterize the activity of various bacterial and mammalian enzymes, including Burkholderia and porcine pancreatic lipase.
    4-Nitrophenyl palmitate
  • HY-W013673
    2,3-Diaminopropionic acid hydrochloride 1482-97-9 ≥98.0%
    2,3-Diaminopropionic acid hydrochloride is the precursor of antibiotics and the siderophore staphyloferrin B. 2,3-Diaminopropionic acid hydrochloride is the inhibitor for polyphenoloxidase (PPO).
    2,3-Diaminopropionic acid hydrochloride
  • HY-W013699
    Chlorhexidine diacetate 56-95-1 ≥98.0%
    Chlorhexidine diacetate is a orally active cationic antimicrobial agent that targets microbial cell membranes. Chlorhexidine diacetate binds to cell membrane phospholipids non-specifically, destroys membrane structure and induces leakage of cell contents. Chlorhexidine diacetate has broad-spectrum bactericidal activity against both Gram-positive and Gram-negative bacteria. Chlorhexidine diacetate can interfere with membrane permeability, cause protein precipitation and energy metabolism disorders, such as rapid inhibition of microbial growth and induction of cell death (necrosis or apoptosis).
    Chlorhexidine diacetate
  • HY-W013967
    1,6-Diphenylhexa-1,3,5-triene 1720-32-7 98.26%
    1,6-Diphenylhexa-1,3,5-triene is a fluorescent probe.
    1,6-Diphenylhexa-1,3,5-triene
  • HY-W016969
    2-Undecanone 112-12-9 98.96%
    2-Undecanone is a volatile organic compound, which inhibits the DnaKJE-ClpB bichaperone dependent refolding of heat-inactivated bacterial luciferases. 2-Undecanone inhibits lung tumorigenesis.
    2-Undecanone
  • HY-W017401
    Benzisothiazolone 2634-33-5 ≥98.0%
    Benzisothiazolone is an isothiazolone fungicide. Benzisothiazolone has growth inhibiting activity against E. coli ATCC 8739 and saccharornyces pombe NCYC 1354. Benzisothiazolone can be used in the study of growth inhibition model .
    Benzisothiazolone
  • HY-W091784
    3'-O-Methylguanosine 10300-27-3 ≥98.0%
    3'-O-Methylguanosine is a methylated nucleoside analogs and a RNA chain terminator. 3'-O-methylguanosine can inhibit early virus-specific RNA synthesis.
    3'-O-Methylguanosine
  • HY-W129596
    Policresulen 101418-00-2
    Policresulen is a competitive inhibitor for DENV2 NS2B/NS3 protease with an IC50 of 0.48 μg/mL. Policresulen can be used as a local hemostatic and antibacterial agent for research of cervical and vaginal inflammation, skin lesions, oral mucosa and gingival inflammation.
    Policresulen
  • HY-W295873
    Cyclo(Phe-Gly) 5037-75-2 98.48%
    Cyclo(Phe-Gly) is a cyclodipeptides with antimicrobial and anticancer activities, isolated from broth culture of endophytic Streptomyces YIM 64018 associated with Paraboea sinensis.
    Cyclo(Phe-Gly)
  • HY-W324882
    Salinazid 495-84-1 99.62%
    Salinazid is an antituberculous compound.
    Salinazid
  • HY-W749694
    Cannflavin B 76735-58-5 98.36%
    Cannflavin B is a flavonoid compound that can be isolated from Cannabis sativa L. Cannflavin B is inhibitors of PGE2 release (IC50: 0.7 μM), mPGES-1 (IC50: 3.7 μM), and 5-lipoxygenase. Cannflavin B has multiple activities such as anti-inflammatory, antioxidant, anti-glycation, anti-ferroptosis, anti-tumor, and anti-Leishmania (IC50: 14 μM). Cannflavin B can also inhibit the TrkB-BDNF signaling pathway.
    Cannflavin B
  • HY-10544
    Tegobuvir 1000787-75-6 98.01%
    Tegobuvir is a specific, covalent inhibitor of the HCV NS5B polymerase.
    Tegobuvir
  • HY-17036
    Naphthoquine phosphate 173531-58-3 99.59%
    Naphthoquine phosphate is a potent and orally active antimalarial agent. Naphthoquine phosphate has thorough killing function for various schizonts of plasmodia, including resistance of P. falciparum to Chloroquine.
    Naphthoquine phosphate
Cat. No. Product Name / Synonyms Application Reactivity