2. Natural Products
  3. Plants
  4. Rubiaceae
  5. Uncaria rhynchophylla (Miq.) Miq. ex Havil.

Uncaria rhynchophylla (Miq.) Miq. ex Havil.

Uncaria rhynchophylla (Miq.) Miq. ex Havil. (23):

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-N0387
    Rhynchophylline 76-66-4 99.75%
    Rhyncholphylline is an alkaloid compound isolated from Uncaria rhynchophyllum. Rhyncholphylline is an EphA4 inhibitor. It has high biological activity and is widely used in anti-inflammatory, neuroprotective and other research..
    Rhynchophylline
  • HY-N0766
    Isorhynchophylline 6859-01-4 99.82%
    Isorhynchophylline is an alkaloid isolated from Crocus sativus with anticancer, antihypertensive, anti-inflammatory, and neuroprotective properties. Isorhynchophylline can be applied to cardiovascular and neurological disorders, and cancer studies.
    Isorhynchophylline
  • HY-N0590
    Corynoxeine 630-94-4 99.97%
    Corynoxeine, isolated from the hook of Uncaria rhynchophylla, is a potent ERK1/ERK2 inhibitor of key PDGF-BB-induced vascular smooth muscle cells (VSMCs) proliferation.
    Corynoxeine
  • HY-N0901
    Corynoxine 6877-32-3 99.89%
    Corynoxine, a tetracyclic oxindole alkaloid, is isolated from the hooks of Uncaria rhynchophylla. Corynoxine is a natural autophagy enhancer that promotes the clearance of alpha-synuclein via Akt/mTOR pathway.
    Corynoxine
  • HY-N2193
    Hirsutine 7729-23-9 99.76%
    Hirsutine, an indole alkaloid of Uncaria rhynchophylla, exhibits anti-cancer activity. Hirsutine induces apoptosis and is a potent Dengue virus inhibitor exhibiting low cytotoxicity.
    Hirsutine
  • HY-N0901A
    Corynoxine B 17391-18-3 99.76%
    Corynoxine B is an alkaloid-based autophagy inducer and α-synuclein aggregation inhibitor that ameliorates Mn-induced dysregulation of autophagy and enhances α-synuclein (α-syn) clearance in Parkinson's disease mice.
    Corynoxine B
  • HY-N2197
    Hirsuteine 35467-43-7 ≥99.0%
    Hirsuteine is an indole alkaloid extracted from Uncaria rhynchophylla. Hirsuteine non-competitively antagonizes nicotine-mediated dopamine release by blocking ion permeation through nicotinic receptor channel complexes.
    Hirsuteine
  • HY-N2411
    Geissoschizine methyl ether 60314-89-8 99.63%
    Geissoschizine methyl ether, a major indole alkaloid found in Uncaria hook, is a major active component of Yokukansan with psychotropic effects. Geissoschizine methyl ether is potent 5-HT1A receptor agonist.
    Geissoschizine methyl ether
  • HY-N0775
    Isocorynoxeine 51014-29-0 99.52%
    Isocorynoxeine, an isorhynchophylline-related alkaloid, exhibits a dose-dependent inhibition of 5-HT2A receptor-mediated current response with an IC50 of 72.4 μM.
    Isocorynoxeine
  • HY-N6946
    Mitraphylline 509-80-8 99.68%
    Mitraphylline is the major pentacyclic oxindolic alkaloid presented in Uncaria tomentosa. Mitraphylline inhibits lipopolysaccharide-mediated activation of primary human neutrophils.
    Mitraphylline
  • HY-N1089
    Vincosamide 23141-27-7 99.72%
    Vincosamide, an alkaloid from Psychotria leiocarpa extract, inhibits the acetylcholinesterase (AChE) activity with anti-inflammatory activity.
    Vincosamide
  • HY-N11478
    Villocarine A 1319743-81-1 98.82%
    Villocarine A is a natural vasorelaxant indole alkaloid.
    Villocarine A
  • HY-N4157
    Isopteropodine 5171-37-9 99.13%
    Isopteropodine is a positive modulator that selectively acts on muscarinic M1 and 5-HT2 receptors. Isopteropodine has an EC50 of 9.92 μM for acetylcholine and 14.5 μM for 5-HT. Isopteropodine also has antibacterial activity against Gram-positive bacteria, with MICs of 150 μg/mL and 250 μg/mL for Staphylococcus aureus and Bacillus subtilis, respectively. Isopteropodine enhances receptor function by increasing the affinity of agonists for receptors and can also inhibit the growth of specific Gram-positive bacteria, and can be used in cognitive impairment and antibacterial research.
    Isopteropodine
  • HY-N0387R
    Rhynchophylline (Standard) 76-66-4
    Rhynchophylline (Standard) is the analytical standard of Rhynchophylline. This product is intended for research and analytical applications. Rhyncholphylline is an alkaloid compound isolated from Uncaria rhynchophyllum. Rhyncholphylline is an EphA4 inhibitor. It has high biological activity and is widely used in anti-inflammatory, neuroprotective and other research..
    Rhynchophylline (Standard)
  • HY-N0590R
    Corynoxeine (Standard) 630-94-4
    Corynoxeine (Standard) is the analytical standard of Corynoxeine. This product is intended for research and analytical applications. Corynoxeine, isolated from the hook of Uncaria rhynchophylla, is a potent ERK1/ERK2 inhibitor of key PDGF-BB-induced vascular smooth muscle cells (VSMCs) proliferation.
    Corynoxeine (Standard)
  • HY-N0775R
    Isocorynoxeine (Standard) 51014-29-0
    Isocorynoxeine (Standard) is the analytical standard of Isocorynoxeine. This product is intended for research and analytical applications. Isocorynoxeine, an isorhynchophylline-related alkaloid, exhibits a dose-dependent inhibition of 5-HT2A receptor-mediated current response with an IC50 of 72.4 μM.
    Isocorynoxeine (Standard)
  • HY-N0901AR
    Corynoxine B (Standard) 17391-18-3
    Corynoxine B Standard is an analytical standard for Corynoxine B. This product is intended for research and analytical applications. Corynoxine B is an alkaloid-type autophagy inducer and α-synuclein aggregation inhibitor that ameliorates Mn-induced dysregulation of autophagy and enhances the clearance of α-synuclein (α-syn) in Parkinson's disease mice.
    Corynoxine B (Standard)
  • HY-N4157R
    Isopteropodine (Standard) 5171-37-9
    Isopteropodine (Standard) is the analytical standard of Isopteropodine (HY-N4157). This product is intended for research and analytical applications. Isopteropodine is a positive modulator that selectively acts on muscarinic M1 and 5-HT2 receptors. Isopteropodine has an EC50 of 9.92 μM for acetylcholine and 14.5 μM for 5-HT. Isopteropodine also has antibacterial activity against Gram-positive bacteria, with MICs of 150 μg/mL and 250 μg/mL for Staphylococcus aureus and Bacillus subtilis, respectively. Isopteropodine enhances receptor function by increasing the affinity of agonists for receptors and can also inhibit the growth of specific Gram-positive bacteria, and can be used in cognitive impairment and antibacterial research.
    Isopteropodine (Standard)
  • HY-N0901B
    Corynoxine hydrochloride
    Corynoxine hydrochloride, a tetracyclic oxindole alkaloid, is isolated from the hooks of Uncaria macrophylla. Corynoxine hydrochloride is a natural autophagy enhancer that promotes the clearance of alpha-synuclein via Akt/mTOR pathway.
    Corynoxine hydrochloride
  • HY-N1793
    3,6,19-Trihydroxy-23-oxo-12-ursen-28-oic acid 131984-82-2
    3,6,19-Trihydroxy-23-oxo-12-ursen-28-oic acid is a Triterpenoids product that can be isolated from the vines of Uncaria rhynchophylla.
    3,6,19-Trihydroxy-23-oxo-12-ursen-28-oic acid