2. Natural Products
  3. Alkaloids
  4. Carbazole Alkaloids

Carbazole Alkaloids

Carbazole Alkaloids (9):

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-W100287
    Murrayafoline A 4532-33-6 99.73%
    Murrayafoline A is a carbazole alkaloid that can be extracted from Murraya tetramera. Murrayafoline A directly targets Specificity protein 1 (Sp1), thereby inhibiting NF-κB and MAPK signaling pathways. Murrayafoline A has anti-neuroinflammatory activity.
    Murrayafoline A
  • HY-101775A
    9-Hydroxyellipticine hydrochloride 52238-35-4 ≥99.0%
    9-Hydroxyellipticine hydrochloride is a inhibitor of Topo II and RyR. 9-Hydroxyellipticine hydrochloride exhibits antitumor, antioxidant and catecholamine-releasing activities. 9-Hydroxyellipticine hydrochloride exhibits IC50 values of 1.6 μM and 1.2μM in Hela S-3 and 293T cells, respectively.
    9-Hydroxyellipticine hydrochloride
  • HY-N13286
    Glycozolidal 51971-09-6 99.92%
    Glycozolidal (compound 12) is a carbazole alkaloid with antibacterial activity against P. gingivalis. Glycozolidal is cytotoxic against human gingival fibroblasts (HGFs) and monocytes (U937) in vitro with IC50 values ​​of 120.86 µg/mL and 97.74 µg/mL, respectively.
    Glycozolidal
  • HY-124557
    Mahanimbine 21104-28-9
    Mahanimbine is an orally active alkaloid from Murraya koenigii. Mahanimbine inhibits progression of high-fat diet (HFD)-induced metabolic complications in mice.
    Mahanimbine
  • HY-100313
    YM-53601 free base 182959-28-0
    YM-53601 free base, a squalene synthase inhibitor, reduces plasma cholesterol and triglyceride levels in vivo. YM-53601 free base inhibits squalene synthase derived from human hepatoma cells with an IC50 of 79 nM. Lipid-lowering agent. YM-53601 free base is also an inhibitor of farnesyl-diphosphate farnesyltransferase 1 (FDFT1) enzyme activity and abrogates HCV propagation.
    YM-53601 free base
  • HY-N13828
    1-Prenyl-2-methoxy-6-formyl-8-hydroxy-9H-carbazole 484678-79-7
    1-Prenyl-2-methoxy-6-formyl-8-hydroxy-9H-carbazole (Compound 19) is a carbazole alkaloid that can be isolated from Murraya koenigii. 1-Prenyl-2-methoxy-6-formyl-8-hydroxy-9H-carbazole exhibits anti-inflammatory and antimicrobial activities. 1-Prenyl-2-methoxy-6-formyl-8-hydroxy-9H-carbazole can inhibit the production of pro-inflammatory cytokines TNF-α and IL-6 . 1-Prenyl-2-methoxy-6-formyl-8-hydroxy-9H-carbazole has IC50 values of 10.9 μM and 95 μM for Bacillus cereus and Staphylococcus aureus, respectively. 1-Prenyl-2-methoxy-6-formyl-8-hydroxy-9H-carbazole can be used in the research of inflammatory and infectious diseases.
    1-Prenyl-2-methoxy-6-formyl-8-hydroxy-9H-carbazole
  • HY-N3594
    Clauszoline M 187110-72-1
    Clauszoline M is a Alkaloids product that can be isolated from the herbs of Clausena dunniana.
    Clauszoline M
  • HY-N3959
    Glycozolinine 5257-08-9
    Glycozolinine (Glycozolinol) is a Iridoids product that can be isolated from the herbs of Duranta repens.
    Glycozolinine
  • HY-101775AR
    9-Hydroxyellipticine hydrochloride (Standard) 52238-35-4
    9-Hydroxyellipticine (hydrochloride) (Standard) is the analytical standard of 9-Hydroxyellipticine (hydrochloride). This product is intended for research and analytical applications. 9-Hydroxyellipticine hydrochloride is a inhibitor of Topo II and RyR. 9-Hydroxyellipticine hydrochloride exhibits antitumor, antioxidant and catecholamine-releasing activities. 9-Hydroxyellipticine hydrochloride exhibits IC50 values of 1.6 μM and 1.2μM in Hela S-3 and 293T cells, respectively.
    9-Hydroxyellipticine hydrochloride (Standard)