(γ-AmNS)UTP trisodium

Cat. No.: HY-137604A: FAQs
Data Sheet Handling Instructions Technical Support

(γ-AmNS)UTP (trisodium) is a fluorescent derivative of UTP and enables the detection of RNA polymerase activity. Incorporation of UMP in RNA results in the release of γ-AmNS-PPi, which has higher intrinsic fluorescence than (γ-AmNS) UTP. (γ-AmNS)UTP (trisodium) can be used for antibacterial and antituberculosis agents study.

For research use only. We do not sell to patients.

(γ-AmNS)UTP trisodium Chemical Structure

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Description	(γ-AmNS)UTP (trisodium) is a fluorescent derivative of UTP and enables the detection of RNA polymerase activity. Incorporation of UMP in RNA results in the release of γ-AmNS-PPi, which has higher intrinsic fluorescence than (γ-AmNS) UTP. (γ-AmNS)UTP (trisodium) can be used for antibacterial and antituberculosis agents study^[1].
Molecular Weight	755.32
Formula	C₁₉H₁₉N₃Na₃O₁₇P₃S
SMILES	O=C(N(C=C1)[C@@H]2O[C@H](COP(OP(OP(NC3=CC=CC4=C3C=CC=C4S(O)(=O)=O)(O[Na])=O)(O[Na])=O)(O[Na])=O)[C@@H](O)[C@H]2O)NC1=O
Shipping	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation	Data Sheet (270 KB) Handling Instructions (2659 KB)
References	[1]. Bhat J, et al. High-throughput screening of RNA polymerase inhibitors using a fluorescent UTP analog. J Biomol Screen. 2006 Dec;11(8):968-76. [Content Brief]