α-Ketoglutaric acid disodium hydrate

Name: α-Ketoglutaric acid disodium hydrate
Brand: MedChemExpress
SKU: HY-W339545A
Rating: 4.5 (1 reviews)

Cat. No.: HY-W339545A Purity: 95.0%: Data Sheet
COA

SDS
Handling Instructions
FAQs
Technical Support

α-Ketoglutaric acid disodium hydrate, an important dicarboxylic acid, is an intermediate in the tricarboxylic acid cycle (TCC) and amino acid metabolism. α-Ketoglutaric acid disodium hydrate can be used as building block chemical for the chemical synthesis of heterocycles, dietary supplement, component of infusion solutions and wound healing compounds, or as main component of new elastomers with a wide range of interesting mechanical and chemical properties.

For research use only. We do not sell to patients.

α-Ketoglutaric acid disodium hydrate Chemical Structure

Size	Stock	Quantity
500 mg	In-stock	Estimated Time of Arrival: December 31
1 g	In-stock	Estimated Time of Arrival: December 31
5 g	Get quote
10 g	Get quote

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Customer Review

Based on 1 publication(s) in Google Scholar

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Biological Activity
Purity & Documentation
References
Customer Review

Description

Molecular Weight

208.08

Formula

C₅H₆Na₂O₆

Appearance

Solid

Color

White to off-white

SMILES

O=C(CCC(C(O[Na])=O)=O)O[Na].O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, stored under nitrogen, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen, away from moisture)

Solvent & Solubility

In Vitro:

H₂O : 175 mg/mL (841.02 mM; Need ultrasonic)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	4.8058 mL	24.0292 mL	48.0584 mL
5 mM	0.9612 mL	4.8058 mL	9.6117 mL
10 mM	0.4806 mL	2.4029 mL	4.8058 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.

The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).

Purity & Documentation

Purity: 95.0%

Select Batch:

Data Sheet (269 KB) SDS (252 KB)

COA (248 KB) HNMR (271 KB)

Handling Instructions (2659 KB)

References

[1]. Otto C, et al. Overproduction and secretion of α-ketoglutaric acid by microorganisms. Appl Microbiol Biotechnol. 2011 Nov;92(4):689-95. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

H₂O	1 mM	4.8058 mL	24.0292 mL	48.0584 mL	120.1461 mL
	5 mM	0.9612 mL	4.8058 mL	9.6117 mL	24.0292 mL
	10 mM	0.4806 mL	2.4029 mL	4.8058 mL	12.0146 mL
	15 mM	0.3204 mL	1.6019 mL	3.2039 mL	8.0097 mL
	20 mM	0.2403 mL	1.2015 mL	2.4029 mL	6.0073 mL
	25 mM	0.1922 mL	0.9612 mL	1.9223 mL	4.8058 mL
	30 mM	0.1602 mL	0.8010 mL	1.6019 mL	4.0049 mL
	40 mM	0.1201 mL	0.6007 mL	1.2015 mL	3.0037 mL
	50 mM	0.0961 mL	0.4806 mL	0.9612 mL	2.4029 mL
	60 mM	0.0801 mL	0.4005 mL	0.8010 mL	2.0024 mL
	80 mM	0.0601 mL	0.3004 mL	0.6007 mL	1.5018 mL
	100 mM	0.0481 mL	0.2403 mL	0.4806 mL	1.2015 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.