2. Others Epigenetics Metabolic Enzyme/Protease
  3. Reference Standards Histone Demethylase Endogenous Metabolite
  4. α-Hydroxyglutaric acid disodium (Standard)

α-Hydroxyglutaric acid disodium (Standard)  (Synonyms: 2-Hydroxyglutarate disodium (Standard); 2-Hydroxyglutaric acid disodium (Standard); 2-Hydroxypentanedioic acid disodium (Standard))

Cat. No.: HY-113038AR
Handling Instructions Technical Support

Ophiopogonin D (Standard) is the analytical standard of Ophiopogonin D. This product is intended for research and analytical applications. Ophiopogonin D, isolated from the tubers of Ophiopogon japonicus, is a rare naturally occurring C29 steroidal glycoside. Ophiopogonin D is a CYP2J3 inducer that significantly inhibits Ang II induced NF-κB nuclear translocation, IκBα down-regulation, intracellular Ca2+ overload and activation of pro-inflammatory cytokines by increasing the expression of CYP2J2/EETs and PPARα in human umbilical vein endothelial cells (HUVECs). Ophiopogonin D has been used to treat inflammatory and cardiovascular diseases for thousands of years.

For research use only. We do not sell to patients.

α-Hydroxyglutaric acid disodium (Standard)

α-Hydroxyglutaric acid disodium (Standard) Chemical Structure

CAS No. : 40951-21-1

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Information

Ophiopogonin D (Standard) is the analytical standard of Ophiopogonin D. This product is intended for research and analytical applications. Ophiopogonin D, isolated from the tubers of Ophiopogon japonicus, is a rare naturally occurring C29 steroidal glycoside. Ophiopogonin D is a CYP2J3 inducer that significantly inhibits Ang II induced NF-κB nuclear translocation, IκBα down-regulation, intracellular Ca2+ overload and activation of pro-inflammatory cytokines by increasing the expression of CYP2J2/EETs and PPARα in human umbilical vein endothelial cells (HUVECs). Ophiopogonin D has been used to treat inflammatory and cardiovascular diseases for thousands of years.

Application

The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
Molecular Weight

192.08

Formula

C5H6Na2O5
CAS No.
SMILES

O=C(O[Na])C(O)CCC(O[Na])=O
Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
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α-Hydroxyglutaric acid disodium (Standard) Related Classifications

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  • Do most proteins show cross-species activity?

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Keywords:

α-Hydroxyglutaric acid disodium (Standard)40951-21-12-Hydroxyglutarate disodium (Standard)2-Hydroxyglutaric acid disodium (Standard)2-Hydroxypentanedioic acid disodium (Standard)Reference StandardsHistone DemethylaseEndogenous MetaboliteCell-permeable5-methylcytosineα-ketoglutaratedioxygenasesIDH1IDH2Inhibitorinhibitorinhibit

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