2. Immunology/Inflammation
  3. FAP
  4. Zilganersen sodium

Zilganersen sodium  (Synonyms: ION373 sodium)

Cat. No.: HY-P3392A Purity: 91.43%
COA
SDS
Handling Instructions Technical Support

Zilganersen sodium is a glial fibrillary acidic protein (GFAP) inhibitor. Zilganersen sodium can be used in Alexander disease (AxD) research.

For research use only. We do not sell to patients.

Gene Regulation Tool

DNA, d([2′-O-(2-methoxyethyl)]m5rC-sp-[2′-O-(2-methoxyethyl)]rA-[2′-O-(2-methoxyethyl)]rG-[2′-O-(2-methoxyethyl)]m5rU-[2′-O-(2-methoxyethyl)]rA-[2′-O-(2-methoxyethyl)]m5rU-T-sp-A-sp-m5C-sp-m5C-sp-T-sp-m5C-sp-T-sp-A-sp-m5C-sp-T-sp-[2′-O-(2-methoxyethyl)]rA-[2′-O-(2-methoxyethyl)]rG-sp-[2′-O-(2-methoxyethyl)]m5rU-sp-[2′-O-(2-methoxyethyl)]m5rC), sodium salt

Zilganersen sodium Chemical Structure

CAS No. : 2305355-64-8

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Based on 1 publication(s) in Google Scholar

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Description

Zilganersen sodium is a glial fibrillary acidic protein (GFAP) inhibitor. Zilganersen sodium can be used in Alexander disease (AxD) research[1][2].

Clinical Trial
Molecular Weight

7478.40

Formula

C230H301N67O127P19S13Na19
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

[Zilganersen (sodium)]
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

-20°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Purity & Documentation

Purity: 91.43%

SDS (252 KB)

COA (245 KB) LCMS (328 KB)

Handling Instructions (2659 KB)
References
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Zilganersen sodium Related Classifications

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Zilganersen2305355-64-8ION373ION 373ION-373FAPFibroblast activation proteinantisense oligonucleotideAlexander diseaseAxDInhibitorinhibitorinhibit

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