YRGDS Fibronectin Fragment

Name: YRGDS Fibronectin Fragment
Brand: MedChemExpress
SKU: HY-P1921
Rating: 4.5 (1 reviews)

Cat. No.: HY-P1921 Purity: 98.86%: Data Sheet
COA

SDS
Handling Instructions
FAQs
Technical Support

YRGDS Fibronectin Fragment is a fibronectin fragment, an adhesion peptide that displays strong binding affinity to thrombin-stimulated platelets.

For research use only. We do not sell to patients.

Custom Peptide Synthesis

YRGDS Fibronectin Fragment Chemical Structure

CAS No. : 134282-68-1

Size	Stock	Quantity
5 mg	In-stock	Estimated Time of Arrival: December 31
10 mg	In-stock	Estimated Time of Arrival: December 31
25 mg	In-stock	Estimated Time of Arrival: December 31
50 mg	Get quote
100 mg	Get quote

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Customer Review

Based on 1 publication(s) in Google Scholar

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αvβ1 αvβ3 αvβ5 αvβ6 αvβ8 α5β1 α1β1 α2β1 α4β1 α9β1 αIIbβ3 α4β7 αLβ2

Biological Activity
Purity & Documentation
References
Customer Review

Description

YRGDS Fibronectin Fragment is a fibronectin fragment, an adhesion peptide that displays strong binding affinity to thrombin-stimulated platelets^[1].

Molecular Weight

596.59

Formula

C₂₄H₃₆N₈O₁₀

CAS No.

134282-68-1

Appearance

Solid

Color

White to off-white

Sequence

Tyr-Arg-Gly-Asp-Ser

Sequence Shortening

YRGDS

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Sealed storage, away from moisture and light

Powder	-80°C	2 years
	-20°C	1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

Solvent & Solubility

In Vitro:

H₂O : 100 mg/mL (167.62 mM; Need ultrasonic)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	1.6762 mL	8.3810 mL	16.7619 mL
5 mM	0.3352 mL	1.6762 mL	3.3524 mL
10 mM	0.1676 mL	0.8381 mL	1.6762 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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In Vivo Dissolution Calculator

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Working solution concentration: mg/mL

This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.

The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).

Purity & Documentation

Purity: 98.86%

Select Batch:

Data Sheet (270 KB) SDS (252 KB)

COA (247 KB) RP-HPLC (271 KB) MS (70 KB) Elemental Analysis Report (107 KB)

Handling Instructions (2659 KB)

References

[1]. Doherty DE, et al. Fibronectin fragments containing the RGDS cell-binding domain mediate monocyte migration into the rabbit lung. A potential mechanism for C5 fragment-induced monocyte lung accumulation. J Clin Invest. 1990 Oct;86(4):1065-75. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

H₂O	1 mM	1.6762 mL	8.3810 mL	16.7619 mL	41.9048 mL
	5 mM	0.3352 mL	1.6762 mL	3.3524 mL	8.3810 mL
	10 mM	0.1676 mL	0.8381 mL	1.6762 mL	4.1905 mL
	15 mM	0.1117 mL	0.5587 mL	1.1175 mL	2.7937 mL
	20 mM	0.0838 mL	0.4190 mL	0.8381 mL	2.0952 mL
	25 mM	0.0670 mL	0.3352 mL	0.6705 mL	1.6762 mL
	30 mM	0.0559 mL	0.2794 mL	0.5587 mL	1.3968 mL
	40 mM	0.0419 mL	0.2095 mL	0.4190 mL	1.0476 mL
	50 mM	0.0335 mL	0.1676 mL	0.3352 mL	0.8381 mL
	60 mM	0.0279 mL	0.1397 mL	0.2794 mL	0.6984 mL
	80 mM	0.0210 mL	0.1048 mL	0.2095 mL	0.5238 mL
	100 mM	0.0168 mL	0.0838 mL	0.1676 mL	0.4190 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.