1. Cell Cycle/DNA Damage
  2. DNA/RNA Synthesis
  3. WRN inhibitor 3

WRN inhibitor 3 (example 110), a cyclic vinyl sulfone compound, is a Wemer Syndrome ATP dependent helicase enzyme (WRN) inhibitor. WRN inhibitor 3 can be used for the research of cancer.

For research use only. We do not sell to patients.

WRN inhibitor 3 Chemical Structure

WRN inhibitor 3 Chemical Structure

CAS No. : 2923009-48-5

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Description

WRN inhibitor 3 (example 110), a cyclic vinyl sulfone compound, is a Wemer Syndrome ATP dependent helicase enzyme (WRN) inhibitor. WRN inhibitor 3 can be used for the research of cancer[1].

In Vitro

WRN inhibitor 3 inhibits WRN-mediated unwinding activity with pIC50 ≤ 7.0 (IC50≥0.1 μM)[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

400.45

Formula

C20H20N2O5S

CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O=C1NC(C(C=CC=C2)=C2OCC3CC3)=CC=C1C(N[C@H]4CS(=O)(C=C4)=O)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Purity & Documentation
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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
WRN inhibitor 3
Cat. No.:
HY-156579
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