2. Metabolic Enzyme/Protease
  3. Phosphodiesterase (PDE)
  4. WIN-63291

WIN-63291 is a selective and orally active phosphodiesterase (PDE) III inhibitor. WIN-63291 can be used for the research of cardiovascular disease.

For research use only. We do not sell to patients.

WIN-63291

WIN-63291 Chemical Structure

CAS No. : 144967-96-4

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WIN-63291 Related Antibodies

Top Publications Citing Use of Products

View All Phosphodiesterase (PDE) Isoform Specific Products:

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PDE1 PDE2 PDE3 PDE4 PDE5 PDE6 PDE7 PDE9 PDE10 PDE11 PDE12 PDE8 Autotaxin

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Description

WIN-63291 is a selective and orally active phosphodiesterase (PDE) III inhibitor. WIN-63291 can be used for the research of cardiovascular disease[1].

IC50 & Target[1]

PDE Ⅲ

 

In Vivo

WIN-63291 (0.1 mg/kg, p.o.) increases LVdP/dtmax by 86% in 30 min in dogs[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Molecular Weight

261.28

Formula

C16H11N3O
CAS No.
SMILES

CC(N1)=C(C=C(C#N)C1=O)C2=CC=C(N=CC=C3)C3=C2
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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WIN-63291 Related Classifications

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

WIN-63291144967-96-4WIN63291WIN 63291Phosphodiesterase (PDE)PhosphodiesterasecardiovascularInhibitorinhibitorinhibit

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HY-105418
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