2. Metabolic Enzyme/Protease PI3K/Akt/mTOR
  3. IPK Superfamily
  4. UNC7437

UNC7437 is a inositol phosphate multikinase (IPMK) inhibitor, with an IC50 value of 26.2 nM. UNC7437 exhibits anti-proliferative activity against glioblastoma cells. UNC7437 decreases the accumulation of InsP4, InsP5, and InsP6 in cells. UNC7437 can be used for the study of TEN-negative glioblastoma models.

For research use only. We do not sell to patients.

UNC7437

UNC7437 Chemical Structure

CAS No. : 2967647-41-0

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UNC7437 Related Antibodies

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Description

UNC7437 is a inositol phosphate multikinase (IPMK) inhibitor, with an IC50 value of 26.2 nM. UNC7437 exhibits anti-proliferative activity against glioblastoma cells. UNC7437 decreases the accumulation of InsP4, InsP5, and InsP6 in cells. UNC7437 can be used for the study of TEN-negative glioblastoma models[1].

In Vitro

UNC7437 (400 nM, 48 h) shows significant anti-proliferative activity against human U251-MG glioblastoma cells[1].
UNC7437 (400 nM, 48 h) effectively inhibits inositol phosphate synthesis in human U251-MG glioblastoma cells, significantly decreasing the accumulation of InsP4, InsP5, and InsP6[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

UNC7437 Related Antibodies
Molecular Weight

293.32

Formula

C18H15NO3
CAS No.
SMILES

O=C(O)/C=C/C1=CC2=C(C3=CC(C)=CC(C)=C3)ON=C2C=C1
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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UNC7437 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

UNC74372967647-41-0UNC 7437UNC-7437IPK SuperfamilyInositiol Polyphosphate Kinase (IPK) Superfamilyinositol phosphate multikinaseglioblastomInhibitorinhibitorinhibit

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