2. Epigenetics
  3. Epigenetic Reader Domain
  4. UNC10142

UNC10142 (Compound 44) is a first-in-class small molecule antagonist of CHD1 that binds with an IC50 value of 1.7 μM. UNC10142 leads to a dose-dependent reduction in viability in PTEN-deficient prostate cancer cells.

For research use only. We do not sell to patients.

UNC10142 Chemical Structure

UNC10142 Chemical Structure

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Description

UNC10142 (Compound 44) is a first-in-class small molecule antagonist of CHD1 that binds with an IC50 value of 1.7 μM. UNC10142 leads to a dose-dependent reduction in viability in PTEN-deficient prostate cancer cells[1].

Molecular Weight

580.80

Formula

C33H52N6O3
Appearance

Solid

Color

White to off-white

SMILES

COC1=C(OCCCN2CCCCC2)C=C(N=C(N3CCCCCCCC3)N=C4N(C)C5CCN(C(C)=O)CC5)C4=C1
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Purity & Documentation
References
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UNC10142 Related Classifications

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

UNC10142UNC 10142UNC-10142Epigenetic Reader DomainCHD1PTENprostate cancer cellsInhibitorinhibitorinhibit

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