1. Anti-infection Cytoskeleton Cell Cycle/DNA Damage
  2. Fungal Microtubule/Tubulin
  3. Tubulin polymerization-IN-83

Tubulin polymerization-IN-83 (Compound A23) is a flavonol derivative. Tubulin polymerization-IN-83 exhibits antifungal activity against various phytopathogenic fungi, with an EC50 of 0.338 μg/mL against Botrytis cinerea. Tubulin polymerization-IN-83 exerts its effects by targeting β-tubulin, disrupting mycelial morphology, and increasing cell membrane permeability, with relatively low ecological and environmental risks.

For research use only. We do not sell to patients.

Tubulin polymerization-IN-83 Chemical Structure

Tubulin polymerization-IN-83 Chemical Structure

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Description

Tubulin polymerization-IN-83 (Compound A23) is a flavonol derivative. Tubulin polymerization-IN-83 exhibits antifungal activity against various phytopathogenic fungi, with an EC50 of 0.338 μg/mL against Botrytis cinerea. Tubulin polymerization-IN-83 exerts its effects by targeting β-tubulin, disrupting mycelial morphology, and increasing cell membrane permeability, with relatively low ecological and environmental risks[1].

Molecular Weight

549.02

Formula

C27H17ClN2O5S2

SMILES

O=C1C(OCC2=NC3=CC=CC=C3N2S(=O)(C4=CC=C(S4)Cl)=O)=C(OC5=C1C=CC=C5)C6=CC=CC=C6

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Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
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Tubulin polymerization-IN-83 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
Tubulin polymerization-IN-83
Cat. No.:
HY-176552
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