Trivalent GalNAc-DBCO

Cat. No.: HY-160291 Purity: 95.13%: Data Sheet
COA

SDS
Handling Instructions
FAQs
Technical Support

Trivalent GalNAc-DBCO can be used for oligonucleotide coupling.

For research use only. We do not sell to patients.

Trivalent GalNAc-DBCO Chemical Structure

Size	Stock	Quantity
5 mg	In-stock	Estimated Time of Arrival: December 31
10 mg	In-stock	Estimated Time of Arrival: December 31
25 mg	In-stock	Estimated Time of Arrival: December 31
50 mg	In-stock	Estimated Time of Arrival: December 31
100 mg	Get quote	Estimated Time of Arrival: December 31
200 mg	Get quote
500 mg	Get quote

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Customer Review

Based on 1 publication(s) in Google Scholar

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Biological Activity
Purity & Documentation
References
Customer Review

Description

Trivalent GalNAc-DBCO can be used for oligonucleotide coupling^[1].

Molecular Weight

1950.18

Formula

C₉₁H₁₄₄N₁₂O₃₄

CAS No.

2765060-22-6

Appearance

Solid

Color

White to off-white

SMILES

CC(N[C@H]([C@H]([C@H]([C@H](O1)CO)O)O)[C@@H]1OCCCCC(NCCCNC(CCOCC(COCCC(NCCCNC(CCCCO[C@H]2[C@@H]([C@H]([C@H]([C@H](O2)CO)O)O)NC(C)=O)=O)=O)(COCCC(NCCCNC(CCCCO[C@H]3[C@@H]([C@H]([C@H]([C@H](O3)CO)O)O)NC(C)=O)=O)=O)NC(CCOCCOCCOCCOCCNC(CCC(N4C5=CC=CC=C5C#CC6=CC=CC=C6C4)=O)=O)=O)=O)=O)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

Solvent & Solubility

In Vitro:

DMSO : 100 mg/mL (51.28 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	0.5128 mL	2.5639 mL	5.1277 mL
5 mM	0.1026 mL	0.5128 mL	1.0255 mL
10 mM	0.0513 mL	0.2564 mL	0.5128 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

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Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

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Working solution concentration: mg/mL

Purity & Documentation

Purity: 95.13%

Select Batch:

Data Sheet (267 KB) SDS (251 KB)

COA (248 KB) HNMR (493 KB) RP-HPLC (225 KB) MS (70 KB)

Handling Instructions (2659 KB)

References

[1]. Guy Hermans, et al. Conjugate of saponin, oligonucleotide and galnac. WO2022055351A1

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	0.5128 mL	2.5639 mL	5.1277 mL	12.8193 mL
	5 mM	0.1026 mL	0.5128 mL	1.0255 mL	2.5639 mL
	10 mM	0.0513 mL	0.2564 mL	0.5128 mL	1.2819 mL
	15 mM	0.0342 mL	0.1709 mL	0.3418 mL	0.8546 mL
	20 mM	0.0256 mL	0.1282 mL	0.2564 mL	0.6410 mL
	25 mM	0.0205 mL	0.1026 mL	0.2051 mL	0.5128 mL
	30 mM	0.0171 mL	0.0855 mL	0.1709 mL	0.4273 mL
	40 mM	0.0128 mL	0.0641 mL	0.1282 mL	0.3205 mL
	50 mM	0.0103 mL	0.0513 mL	0.1026 mL	0.2564 mL