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  3. Drug Derivative
  4. Trabectedin derivative 2 TFA

Trabectedin derivative 2 TFA (compound PL-12) is a Trabectedin derivative that can be used for the study of cancer.

For research use only. We do not sell to patients.

Trabectedin derivative 2 TFA

Trabectedin derivative 2 TFA Chemical Structure

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Based on 1 publication(s) in Google Scholar

Trabectedin derivative 2 TFA Related Antibodies

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Description

Trabectedin derivative 2 TFA (compound PL-12) is a Trabectedin derivative that can be used for the study of cancer[1].

Molecular Weight

853.86

Formula

C41H42F3N5O10S
Appearance

Solid

Color

White to off-white

SMILES

N#C[C@@H]([C@]1([H])CC2=CC(C)=C3OC)N([C@](CO4)([H])C5=C(OCO6)C6=C7C)[C@@]([C@@](N1C)([H])C2=C3O)([H])[C@@](SC[C@](C8=CC=C9N)(NCCC8=C9)C4=O)([H])C5=C7OC(C)=O.O=C(O)C(F)(F)F
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

-20°C, sealed storage, away from moisture and light

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

Solvent & Solubility
In Vitro: 

DMSO : ≥ 100 mg/mL (117.12 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.1712 mL 5.8558 mL 11.7115 mL
5 mM 0.2342 mL 1.1712 mL 2.3423 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 1.1712 mL 5.8558 mL 11.7115 mL 29.2788 mL
5 mM 0.2342 mL 1.1712 mL 2.3423 mL 5.8558 mL
10 mM 0.1171 mL 0.5856 mL 1.1712 mL 2.9279 mL
15 mM 0.0781 mL 0.3904 mL 0.7808 mL 1.9519 mL
20 mM 0.0586 mL 0.2928 mL 0.5856 mL 1.4639 mL
25 mM 0.0468 mL 0.2342 mL 0.4685 mL 1.1712 mL
30 mM 0.0390 mL 0.1952 mL 0.3904 mL 0.9760 mL
40 mM 0.0293 mL 0.1464 mL 0.2928 mL 0.7320 mL
50 mM 0.0234 mL 0.1171 mL 0.2342 mL 0.5856 mL
60 mM 0.0195 mL 0.0976 mL 0.1952 mL 0.4880 mL
80 mM 0.0146 mL 0.0732 mL 0.1464 mL 0.3660 mL
100 mM 0.0117 mL 0.0586 mL 0.1171 mL 0.2928 mL
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Trabectedin derivative 2 TFA Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Trabectedin derivative 2Trabectedin derivative2Trabectedin derivative-2Drug DerivativeDrug derivativeTrabectedin derivativecancerInhibitorinhibitorinhibit

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