2. Apoptosis
  3. TNF Receptor
  4. TNF-α-IN-24

TNF-α-IN-24 (Example 15) is a TNF-α inhibitor with an IC50 of 4.1 nM. TNF-α-IN-24 can be used in study of inflammatory and autoimmune disorders such as rheumatoid arthritis and Crohn’s disease.

For research use only. We do not sell to patients.

TNF-α-IN-24 Chemical Structure

TNF-α-IN-24 Chemical Structure

CAS No. : 3075686-66-4

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TNF-α-IN-24 Related Antibodies

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TNFRSF1A/CD120a TNFRSF4 TNFRSF5/CD40 TNFRSF6/Fas/CD95 TNFRSF7/CD27 TNFRSF8/CD30 TNFRSF9/4-1BB/CD137 TNFRSF12A/TWEAK TNFRSF16/NGF Receptor/CD271 TNFRSF18/GITR/CD357

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Description

TNF-α-IN-24 (Example 15) is a TNF-α inhibitor with an IC50 of 4.1 nM. TNF-α-IN-24 can be used in study of inflammatory and autoimmune disorders such as rheumatoid arthritis and Crohn’s disease[1].

Molecular Weight

502.52

Formula

C27H24F2N6O2
CAS No.
SMILES

CN([C@H]1C2=NN(C=CC(C3=CN=C(C4(CCC4)N)N=C3)=C5)C5=C2[C@@H](C6=C(OC(F)F)C=CC=C67)C1)C7=O
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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TNF-α-IN-24 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

TNF-α-IN-243075686-66-4TNF ReceptorTumor Necrosis Factor ReceptorTNFRCaco2 cellsrheumatoid arthritisCrohn’s diseaseInhibitorinhibitorinhibit

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