2. Cell Cycle/DNA Damage NF-κB Immunology/Inflammation
  3. Deubiquitinase NF-κB IFNAR
  4. Subquinocin

Subquinocin is a CYLD inhibitor that inhibits USP family deubiquitinases (DUBs). Subquinocin enhances the activation of NF-κB and IFN pathways by inhibiting CYLD. Subquinocin promotes RIG-I-mediated activation of IRF3 and/or IRF7 in the interferon pathway.

For research use only. We do not sell to patients.

Subquinocin

Subquinocin Chemical Structure

Size Price Stock Quantity
5 mg Get quote 6 - 8 weeks 5 - 7 weeks 5 - 7 weeks
10 mg Get quote 6 - 8 weeks 5 - 7 weeks 5 - 7 weeks
25 mg Get quote 6 - 8 weeks 5 - 7 weeks 5 - 7 weeks
50 mg Get quote 6 - 8 weeks 5 - 7 weeks 5 - 7 weeks
100 mg   Get quote  
200 mg   Get quote  
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Customer Review

Based on 1 publication(s) in Google Scholar

Subquinocin Related Antibodies

Top Publications Citing Use of Products

View All Deubiquitinase Isoform Specific Products:

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USP1 USP2 USP7 USP8 USP10 USP30 UCHL1

View All NF-κB Isoform Specific Products:

View All Isoforms
NF-κB NF-κB1/p50 RelA/p65 RelB c-Rel

  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description

Subquinocin is a CYLD inhibitor that inhibits USP family deubiquitinases (DUBs). Subquinocin enhances the activation of NF-κB and IFN pathways by inhibiting CYLD. Subquinocin promotes RIG-I-mediated activation of IRF3 and/or IRF7 in the interferon pathway[1].

Molecular Weight

405.51

Formula

C20H27N3O4S
SMILES

O=C1N(CC(C)C)C=C(NC(NC(CCSC)C(OC)=O)=O)C2=C1C=CC=C2
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Subquinocin Related Classifications

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This equation is commonly abbreviated as: C1V1 = C2V2

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

SubquinocinDeubiquitinaseNF-κBIFNARDUBsNuclear factor-κBNuclear factor-kappaBInterferon-α/β receptorInterferon-alpha/beta receptorUSPdeubiquitinasesRIG-Itumor suppressorInhibitorinhibitorinhibit

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HY-176426
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