2. Metabolic Enzyme/Protease
  3. Lipoxygenase
  4. Setileuton tosylate

Setileuton tosylate  (Synonyms: MK-0633 tosylate)

Cat. No.: HY-10437A
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Setileuton tosylate is an inhibitor for 5-lipoxygenase, that inhibits the oxidation of arachidonic acid by recombinant human 5-LO, and the production of LTB4 in calcium ionophore-stimulated human whole blood, with IC50 of 3.9 and 52 nM, respectively.

For research use only. We do not sell to patients.

Setileuton tosylate

Setileuton tosylate Chemical Structure

CAS No. : 1137737-87-1

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Setileuton tosylate Related Antibodies

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Description

Setileuton tosylate is an inhibitor for 5-lipoxygenase, that inhibits the oxidation of arachidonic acid by recombinant human 5-LO, and the production of LTB4 in calcium ionophore-stimulated human whole blood, with IC50 of 3.9 and 52 nM, respectively[1].

Molecular Weight

635.58

Formula

C29H25F4N3O7S
CAS No.
SMILES

O=S(O)(C1=CC=C(C=C1)C)=O.O=C2C=C(C3=CC=C(C=C3)F)C4=CC=C(CNC5=NN=C([C@](CC)(O)C(F)(F)F)O5)C=C4O2
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Room temperature in continental US; may vary elsewhere.
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Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
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Setileuton tosylate Related Classifications

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Setileuton1137737-87-1MK-0633MK0633MK 0633LipoxygenaseLOXchronic obstructive pulmonary diseaseleukotrieneLTB4Inhibitorinhibitorinhibit

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