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Results for "

urticarial

" in MedChemExpress (MCE) Product Catalog:

19

Inhibitors & Agonists

2

Inhibitory Antibodies

4

Isotope-Labeled Compounds

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-100657
    meta-Fexofenadine

    meta-MDL-16455; meta-Terfenadine carboxylate

    		 Drug Metabolite Inflammation/Immunology
    meta-Fexofenadine (meta-MDL-16455) is an impurity of Fexofenadine . Fexofenadine, a H1R antagonist, is an anti-allergic agent used in seasonal allergic rhinitis and chronic idiopathic urticarial .
    meta-Fexofenadine
  • HY-B0801A
    Fexofenadine hydrochloride
    5 Publications Verification

    MDL-16455 hydrochloride; Terfenadine carboxylate hydrochloride

    		 Histamine Receptor Inflammation/Immunology Cancer
    Fexofenadine (MDL-16455) hydrochloride is an orally active and nonsedative H1 receptor antagonist. Fexofenadine hydrochloride can be used in allergic rhinitis and chronic idiopathic urticarial research .
    Fexofenadine hydrochloride
  • HY-B0801
    Fexofenadine
    5 Publications Verification

    MDL-16455; Terfenadine carboxylate

    		 Histamine Receptor Inflammation/Immunology Cancer
    Fexofenadine (MDL-16455) is an orally active and nonsedative H1 receptor antagonist. Fexofenadine can be used in allergic rhinitis and chronic idiopathic urticarial research .
    Fexofenadine
  • HY-B0164
    Mizolastine

    		Histamine Receptor Inflammation/Immunology
    Mizolastine is an orally active, high affinity and specific peripheral histamine H1 receptor antagonist (second generation antihistamine). Mizolastine effectively inhibits mRNA expression of VEGF165, VEGF120, TNF-α and KC. Mizolastine can be used in studies of allergic rhinitis and chronic idiopathic urticarial .
    Mizolastine
  • HY-100657R
    meta-Fexofenadine (Standard)

    meta-MDL-16455 (Standard); meta-Terfenadine carboxylate (Standard)

    		 Drug Metabolite Reference Standards Inflammation/Immunology
    meta-Fexofenadine (Standard) is the analytical standard of meta-Fexofenadine. This product is intended for research and analytical applications. meta-Fexofenadine (meta-MDL-16455) is an impurity of Fexofenadine . Fexofenadine, a H1R antagonist, is an anti-allergic agent used in seasonal allergic rhinitis and chronic idiopathic urticarial .
    meta-Fexofenadine (Standard)
  • HY-B0801R
    Fexofenadine (Standard)

    		Histamine Receptor Inflammation/Immunology Cancer
    Fexofenadine (Standard) is the analytical standard of Fexofenadine. This product is intended for research and analytical applications. Fexofenadine (MDL-16455) is an orally active and nonsedative H1 receptor antagonist. Fexofenadine can be used in allergic rhinitis and chronic idiopathic urticarial research .
    Fexofenadine (Standard)
  • HY-B0801S4
    Fexofenadine-d3-1

    MDL-16455-d3-1; Terfenadine carboxylate-d3-1

    		 Histamine Receptor Isotope-Labeled Compounds Inflammation/Immunology
    Fexofenadine-d3-1 fumarate is deuterated labeled Fexofenadine (HY-B0801). Fexofenadine (MDL-16455) is an orally active and nonsedative H1 receptor antagonist. Fexofenadine can be used in allergic rhinitis and chronic idiopathic urticarial research .
    Fexofenadine-d3-1
  • HY-B0164A
    Mizolastine dihydrochloride

    		Histamine Receptor Inflammation/Immunology
    Mizolastine dihydrochloride is an orally active, high affinity and specific peripheral histamine H1 receptor antagonist (second generation antihistamine). Mizolastine dihydrochloride effectively inhibits mRNA expression of VEGF165, VEGF120, TNF-α and KC. Mizolastine dihydrochloride can be used in studies of allergic rhinitis and chronic idiopathic urticarial .
    Mizolastine dihydrochloride
  • HY-B0164R
    Mizolastine (Standard)

    		Reference Standards Histamine Receptor Inflammation/Immunology
    Mizolastine (Standard) is the analytical standard of Mizolastine. This product is intended for research and analytical applications. Mizolastine is an orally active, high affinity and specific peripheral histamine H1 receptor antagonist (second generation antihistamine). Mizolastine effectively inhibits mRNA expression of VEGF165, VEGF120, TNF-α and KC. Mizolastine can be used in studies of allergic rhinitis and chronic idiopathic urticarial .
    Mizolastine (Standard)
  • HY-131274
    Fexofenadine Impurity F

    		Drug Metabolite Others
    Fexofenadine Impurity F is the impurity of Fexofenadine. Fexofenadine, a H1R antagonist, is an anti-allergic agent used in seasonal allergic rhinitis and chronic idiopathic urticarial .
    Fexofenadine Impurity F
  • HY-B0801AS
    Fexofenadine-d10 hydrochloride

    MDL-16455-d10 hydrochloride; Terfenadine carboxylate-d10 hydrochloride

    		 Isotope-Labeled Compounds Histamine Receptor Inflammation/Immunology Endocrinology
    Fexofenadine-d10 (hydrochloride) is deuterium labeled Fexofenadine (hydrochloride). Fexofenadine hydrochloride (MDL-16455 hydrochloride), a H1R antagonist, is an anti-allergic agent used in seasonal allergic rhinitis and chronic idiopathic urticarial (person aged ≥16 years) .
    Fexofenadine-d10 hydrochloride
  • HY-B0801S2
    Fexofenadine-d3

    MDL-16455-d3; Terfenadine carboxylate-d3

    		 Histamine Receptor Inflammation/Immunology
    Fexofenadine-d3 is the deuterium labeled Fexofenadine . Fexofenadine (MDL-16455) is an orally active and nonsedative H1 receptor antagonist. Fexofenadine can be used in allergic rhinitis and chronic idiopathic urticarial research .
    Fexofenadine-d3
  • HY-B0801AR
    Fexofenadine hydrochloride (Standard)

    MDL-16455 hydrochloride (Standard); Terfenadine carboxylate hydrochloride (Standard)

    		 Reference Standards Histamine Receptor Inflammation/Immunology
    Fexofenadine (hydrochloride) (Standard) is the analytical standard of Fexofenadine (hydrochloride). This product is intended for research and analytical applications. Fexofenadine (MDL-16455) hydrochloride is an orally active and nonsedative H1 receptor antagonist. Fexofenadine hydrochloride can be used in allergic rhinitis and chronic idiopathic urticarial research .
    Fexofenadine hydrochloride (Standard)
  • HY-100657S
    Meta-Fexofenadine-d6

    meta-MDL-16455-d6; meta-Terfenadine carboxylate-d6

    		 Isotope-Labeled Compounds Inflammation/Immunology
    Meta-Fexofenadine-d6 is the deuterium labeled meta-Fexofenadine. meta-Fexofenadine (meta-MDL-16455) is an impurity of Fexofenadine . Fexofenadine, a H1R antagonist, is an anti-allergic agent used in seasonal allergic rhinitis and chronic idiopathic urticarial .
    Meta-Fexofenadine-d6
  • HY-B0725A
    Doxepin

    		mTOR PI3K Akt Neurological Disease Cancer
    Doxepin inhibits reuptake of serotonin and norepinephrine as a tricyclic antidepressant. Doxepin has therapeutic effects in atopic dermatitis，chronic urticarial，can improve cognitive processes， protect central nervous system. Doxepin has also been proposed as a protective factor against oxidative stress .
    Doxepin
  • HY-P99488
    Briquilimab

    JSP-191; AMG-191

    		 c-Kit Inflammation/Immunology Cancer
    Briquilimab (JSP-191 or AMG-191) is a humanized IgG1 monoclonal antibody that binds human CD117 (c-Kit). Briquilimab blocks the interaction between CD117 receptor and stem cell factor on various CD117 expressing tissues. Briquilimab can lead to inhibition of SCF/c-Kit signaling and MC apoptosis. Briquilimab is a non-toxic approach to target and deplete HSC, enabling blood and immune reconstitution with minimal toxicity with the other agents being used for transient immune suppression to prevent immunologic rejection. Briquilimab can be used in various disease research such as severe combined immunodeficiency (SCID), myelodyplastic syndromes (MDS), acute myeloid leukemia (AML), chronic spontaneous urticarial (CSU), chronic inducible urticarial (CIndU) and asthema .
    Briquilimab
  • HY-P99300
    Ligelizumab
    1 Publications Verification

    QGE 031; Anti-IGHE Recombinant Antibody

    		 Fc Receptor (FcR) Inflammation/Immunology
    Ligelizumab (QGE 031) is a humanized high-affinity anti-immunoglobulin IgE monoclonal antibody. Ligelizumab selectively inhibits the binding of IgE to the high-affinity receptor FcεRI, while the inhibitory effect on the low-affinity receptor CD23 is weak. Ligelizumab can inhibit the activation of effector cells such as mast cells and Basophil, while reducing the production of IgE by B cells, and restoring the IFN-α production and regulatory T cell (Treg) induction function of plasmacytoid dendritic cells (pDC). Ligelizumab can be used in the study of allergic diseases (such as chronic spontaneous urticaria, allergic asthma) .
    Ligelizumab
  • HY-B0725
    Doxepin Hydrochloride
    4 Publications Verification

    		 Histamine Receptor Cytochrome P450 Neurological Disease Cancer
    Doxepin hydrochloride is an orally active tricyclic antidepressant agent. Doxepin hydrochloride is a potent and selective histamine receptor H1 antagonist. Doxepin hydrochloride is also a potent CYP450 inhibitor and significantly inhibits CYP450 2C19 and 1A2 . Doxepin inhibits reuptake of serotonin and norepinephrine as a tricyclic antidepressant .
    . Doxepin has therapeutic effects in atopic dermatitis，chronic urticarial，can improve cognitive processes， protect central nervous system .
    . Doxepin has also been proposed as a protective factor against oxidative stress .
    .
    Doxepin Hydrochloride
  • HY-B0725R
    Doxepin Hydrochloride (Standard)

    		Reference Standards Histamine Receptor Cytochrome P450 Neurological Disease Cancer
    Doxepin (Hydrochloride) (Standard) is the analytical standard of Doxepin (Hydrochloride). This product is intended for research and analytical applications. Doxepin hydrochloride is an orally active tricyclic antidepressant agent. Doxepin hydrochloride is a potent and selective histamine receptor H1 antagonist. Doxepin hydrochloride is also a potent CYP450 inhibitor and significantly inhibits CYP450 2C19 and 1A2 . Doxepin inhibits reuptake of serotonin and norepinephrine as a tricyclic antidepressant .
    . Doxepin has therapeutic effects in atopic dermatitis，chronic urticarial，can improve cognitive processes， protect central nervous system .
    . Doxepin has also been proposed as a protective factor against oxidative stress .
    .
    Doxepin Hydrochloride (Standard)

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