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Results for "

tri-GalNAc

" in MedChemExpress (MCE) Product Catalog:

11

Inhibitors & Agonists

4

Peptides

2

Click Chemistry

1

Oligonucleotides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-147102
    tri-GalNAc biotin

    		LYTACs Metabolic Disease
    tri-GalNAc biotin is a biotinylated ASGPR (Asialoglycoprotein receptor) ligand. tri-GalNAc biotin promotes cellular uptake of neutravidin (NA) via ASGPR. tri-GalNAc biotin delivers neutravidin to lysosomes for degradation. tri-GalNAc biotin can be used for research of LYsosome TArgeting Chimera (LYTAC) .
    tri-GalNAc biotin
  • HY-145368B
    Tri-GalNAc(OAc)3-Perfluorophenyl

    		LYTACs Metabolic Disease
    Tri-GalNAc(OAc)3-Perfluorophenyl is a pentafluorophenyl modified Tri-GalNAc(OAc)3 (HY-148118), a tri-GalNAc ligand that can be used for the synthesis of GalNAc-LYTAC. GalNAc-LYTAC engages the asialoglycoprotein receptor for targeted protein degradation.Tri-GalNAc(OAc)3-Perfluorophenyl can be used for the study of liver metabolism .
    Tri-GalNAc(OAc)3-Perfluorophenyl
  • HY-139482
    tri-GalNAc-COOH

    		LYTACs Cancer
    tri-GalNAc-COOH is an asialoglycoprotein receptor (ASGPR) ligand that can be used for LYsosome TArgeting Chimera (LYTAC) research .
    tri-GalNAc-COOH
  • HY-148118
    Tri-GalNAc(OAc)3

    		LYTACs Cancer
    Tri-GalNAc(OAc)3is a trivalent N-acetylgalactosamine (GalNAc) derivative that can be used to synthesize GalNAc-LYTAC. Tri-GalNAc is a specific ligand targeting the asialoglycoprotein receptor (ASGPR), mediating the endocytosis and transport of cell surface proteins (such as EGFR, HER2) to lysosomes for degradation by lysosomal targeting chimeras (LYTACs). Tri-GalNAc significantly reduces the level of target proteins and inhibits downstream signaling pathways (such as EGFR-mediated Akt and MAPK signals). Tri-GalNAc(OAc)3can be used for hepatocyte targeting studies, and can degrade carcinogenic membrane proteins and inhibit tumor cell proliferation in liver cancer cell models .
    Tri-GalNAc(OAc)3
  • HY-147354
    TriGalNAc CBz

    		LYTACs Cardiovascular Disease
    TriGalNAc CBz is a GalNAc derivative and tri-GalNAc is an asialoglycoprotein receptor (ASGPR) ligand. TriGalNAc CBz can be used for mRNA drug delivery as well as lysosomal targeted chimerism (LYTAC) studies .
    TriGalNAc CBz
  • HY-148118A
    Tri-GalNAc(OAc)3 TFA

    		LYTACs Cancer
    Tri-GalNAc(OAc)3 TFA is a trivalent N-acetylgalactosamine (GalNAc) derivative that can be used to synthesize GalNAc-LYTAC. Tri-GalNAc is a specific ligand targeting the asialoglycoprotein receptor (ASGPR), mediating the endocytosis and transport of cell surface proteins (such as EGFR, HER2) to lysosomes for degradation by lysosomal targeting chimeras (LYTACs). Tri-GalNAc significantly reduces the level of target proteins and inhibits downstream signaling pathways (such as EGFR-mediated Akt and MAPK signals). Tri-GalNAc(OAc)3 TFA can be used for hepatocyte targeting studies, and can degrade carcinogenic membrane proteins and inhibit tumor cell proliferation in liver cancer cell models .
    Tri-GalNAc(OAc)3 TFA
  • HY-148476
    Tri-GalNAc-DBCO

    		LYTACs Biochemical Assay Reagents Metabolic Disease
    Tri-GalNAc-DBCO is a synthetic ligand composed of three GalNAc units linked to DBCO. Tri-GalNAc-DBCO can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing an azide group. Tri-GalNAc-DBCO specifically binds to the asialoglycoprotein receptor (ASGPR). Tri-GalNAc-DBCO directs the conjugated molecule to the lysosome for degradation via receptor-mediated endocytosis. Tri-GalNAc-DBCO can be used in the study of liver-related diseases .
    Tri-GalNAc-DBCO
  • HY-157950
    DSPE-PEG2000-triGalNAc ammonium

    		Liposome Cancer
    DSPE-PEG2K-triGalNAc is a polar lipid composed of DSPE and tri-N-acetylgalactosamine that can be used to construct liposomes target to asialoglycoprotein receptor (ASGPR).
    DSPE-PEG2000-triGalNAc ammonium
  • HY-145013
    tri-GalNAc-COOH (acetylation)

    		LYTACs Others
    tri-GalNAc-COOH acetylation is the acetylated and modified form of tri-GalNAc-COOH. tri-GalNAc-COOH acetylation can be used for the synthesis of LYTAC.
    tri-GalNAc-COOH (acetylation)
  • HY-173261
    Tri-GalNAc(OAc)3-Cbz

    		Biochemical Assay Reagents Others
    Tri-GalNAc(OAc)3-Cbz is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
    Tri-GalNAc(OAc)3-Cbz
  • HY-P5045
    Fmoc-Thr(GalNAc(Ac)3-β-D)-OH

    		Amino Acid Derivatives Inflammation/Immunology Cancer
    Fmoc-Thr(GalNAc(Ac)3-β-D)-OH inhibits cancer cell growth, through targeting intricate cancer-specific pathways while simultaneously strengthening immunologic response .
    Fmoc-Thr(GalNAc(Ac)3-β-D)-OH

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