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sulfide

" in MedChemExpress (MCE) Product Catalog:

66

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3

Fluorescent Dye

4

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12

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5

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6

Isotope-Labeled Compounds

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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-W013186S
    Lansoprazole sulfide-d4

    AG-1777-d4

    		 Proton Pump Bacterial Inflammation/Immunology
    Lansoprazole sulfide-d4 is a deuterium labeled Lansoprazole Sulfide. Lansoprazole Sulfide is an active metabolite of the proton pump inhibitor Lansoprazole. Lansoprazole Sulfide is an orally active anti-TB (Mycobacterium tuberculosis) agent with IC50 values of 0.59 μM intracellularly and 0.46 μM in broth .
    Lansoprazole sulfide-d4
  • HY-128447
    Allyl methyl sulfide

    		Endogenous Metabolite SOD NF-κB GLUT Metabolic Disease Inflammation/Immunology
    Allyl methyl sulfide is an orally active organic sulfide. Allyl methyl sulfide is one of the main active ingredients in garlic volatile metabolites. Allyl methyl sulfide can be extracted from garlic. Allyl methyl sulfide enhances SOD activity, inhibits NF-κB signaling pathway, and upregulates pancreatic GLUT2 expression. Allyl methyl sulfide has significant antioxidant, anti-inflammatory and hypoglycemic activities. Allyl methyl sulfide can be used in the research of diabetes and its complications .
    Allyl methyl sulfide
  • HY-G0006
    Omeprazole sulfide

    Ufiprazole

    		 Biochemical Assay Reagents Infection Endocrinology
    Omeprazole sulfide is an Esomeprazole (HY-17021) precursor. Omeprazole sulfide can be converted to Esomeprazole by Lysinibacillus sp. B71. Esomeprazole can inhibit gastric H +/ + ATP enzyme. Omeprazole sulfide is mainly used in gastroesophageal reflux disease, gastric ulcer and antibacterial research .
    Omeprazole sulfide
  • HY-B1786A
    (E/Z)-Sulindac sulfide

    		γ-secretase Amyloid-β Neurological Disease
    (E/Z)-Sulindac sulfide is a potent γ-secretase modulator (GSM). (E/Z)-Sulindac sulfide selectively reduces Aβ42 production in favor of shorter Aβ species. (E/Z)-Sulindac sulfide can be used for researching Alzheimer’s disease .
    (E/Z)-Sulindac sulfide
  • HY-B1786S
    Sulindac sulfide-d3

    cis-Sulindac sulfide-d3

    		 Isotope-Labeled Compounds γ-secretase Neurological Disease
    Sulindac sulfide-d3 is deuterium labeled Sulindac sulfide. Sulindac sulfide is a noncompetitive γ-secretase inhibitor, with an IC50 of 20.2 μM for γ42-secretase activity.
    Sulindac sulfide-d3
  • HY-128447R
    Allyl methyl sulfide (Standard)

    		Reference Standards Endogenous Metabolite SOD NF-κB GLUT Metabolic Disease Inflammation/Immunology
    Allyl methyl sulfide (Standard) is the analytical standard of Allyl methyl sulfide (HY-128447). This product is intended for research and analytical applications. Allyl methyl sulfide is an orally active organic sulfide. Allyl methyl sulfide is one of the main active ingredients in garlic volatile metabolites. Allyl methyl sulfide can be extracted from garlic. Allyl methyl sulfide enhances SOD activity, inhibits NF-κB signaling pathway, and upregulates pancreatic GLUT2 expression. Allyl methyl sulfide has significant antioxidant, anti-inflammatory and hypoglycemic activities. Allyl methyl sulfide can be used in the research of diabetes and its complications .
    Allyl methyl sulfide (Standard)
  • HY-B1786R
    Sulindac sulfide (Standard)

    		Drug Metabolite γ-secretase Neurological Disease
    Sulindac sulfide (Standard) is the analytical standard of Sulindac sulfide. This product is intended for research and analytical applications. Sulindac sulfide is a noncompetitive γ-secretase inhibitor, with an IC50 of 20.2 μM for γ42-secretase activity.
    Sulindac sulfide (Standard)
  • HY-W250123R
    Dibutyl sulfide (Standard)

    		Biochemical Assay Reagents Others
    Dibutyl sulfide (Standard) is the analytical standard of Dibutyl sulfide. This product is intended for research and analytical applications. Dibutyl sulfide is an oily liquid commonly used as a solvent, extractant and flavoring agent in various industrial processes, especially in the production of petroleum products, polymers and food additives. Dibutyl sulfide has unique chemical properties that make it an active ingredient in many applications requiring high solvency and low volatility.
    Dibutyl sulfide (Standard)
  • HY-G0006R
    Omeprazole sulfide (Standard)

    Ufiprazole (Standard)

    		 Drug Metabolite Others
    Omeprazole sulfide (Standard) is the analytical standard of Omeprazole sulfide. This product is intended for research and analytical applications. Omeprazole sulfide is an Esomeprazole (HY-17021) precursor. Omeprazole sulfide can be converted to Esomeprazole by Lysinibacillus sp. B71. Esomeprazole can inhibit gastric H +/ + ATP enzyme. Omeprazole sulfide is mainly used in gastroesophageal reflux disease, gastric ulcer and antibacterial research .
    Omeprazole sulfide (Standard)
  • HY-N12977
    Dipropenyl sulfide

    		Others Others
    Dipropenyl sulfide is a constituent of Garlic oil, onion oil .
    Dipropenyl sulfide
  • HY-W003467R
    Rabeprazole Sulfide (Standard)

    		Proton Pump Bacterial Infection Inflammation/Immunology
    Rabeprazole Sulfide (Standard) is the analytical standard of Rabeprazole Sulfide. This product is intended for research and analytical applications. Rabeprazole Sulfide is an active metabolite of Rabeprazole. Rabeprazole is a proton pump inhibitor that suppresses gastric acid secretion through an interaction with (H +/K +)-ATPase in gastric parietal cells. Rabeprazole markedly inhibits the motility of H. pylori. Rabeprazole has the potential for various peptic diseases treatment .
    Rabeprazole Sulfide (Standard)
  • HY-B1786
    Sulindac sulfide
    1 Publications Verification

    cis-Sulindac sulfide

    		 Drug Metabolite γ-secretase Neurological Disease
    Sulindac sulfide is a noncompetitive γ-secretase inhibitor, with an IC50 of 20.2 μM for γ42-secretase activity.
    Sulindac sulfide
  • HY-W016033
    Pantoprazole sulfide

    		Drug Metabolite Proton Pump Metabolic Disease
    Pantoprazole sulfide is a metabolite of Pantoprazole (HY-17507), which is a proton-pump inhibitor .
    Pantoprazole sulfide
  • HY-141776S
    Omeprazole sulfide-d3

    Ufiprazole-d3

    		 Drug Metabolite Others
    Omeprazole sulfide-d3 is the deuterium labeled Omeprazole sulfide. Omeprazole metabolite Omeprazole sulfide (Ufiprazole) is a metabolite of Omeprazole, which is a proton pump inhibitor.
    Omeprazole sulfide-d3
  • HY-W013186
    Lansoprazole sulfide

    AG-1777

    		 Drug Metabolite Bacterial Inflammation/Immunology Cancer
    Lansoprazole sulfide is an active metabolite of Lansoprazole by cytochrome P450, possesses anti-cancer activity. Lansoprazole sulfide is an anti-tuberculous agent, with an IC50 of 0.59 µM for M. tb .
    Lansoprazole sulfide
  • HY-W250123
    Dibutyl sulfide

    		Biochemical Assay Reagents Others
    Dibutyl sulfide is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
    Dibutyl sulfide
  • HY-138187
    4-Hydroxy omeprazole sulfide

    		Proton Pump Metabolic Disease
    4-Hydroxy omeprazole sulfide is a metabolite of the proton pump inhibitor Omeprazole (HY-B0113) .
    4-Hydroxy omeprazole sulfide
  • HY-W013186S1
    Lansoprazole sulfide-13C6

    AG-1777-13C6

    		 Isotope-Labeled Compounds Drug Metabolite Others
    Lansoprazole sulfide- 13C6 is a deuterated labeled Lansoprazole sulfide .
    Lansoprazole sulfide-13C6
  • HY-W003467
    Rabeprazole Sulfide

    		Proton Pump Bacterial Infection Inflammation/Immunology
    Rabeprazole Sulfide is an active metabolite of Rabeprazole. Rabeprazole is a proton pump inhibitor that suppresses gastric acid secretion through an interaction with (H +/K +)-ATPase in gastric parietal cells. Rabeprazole markedly inhibits the motility of H. pylori. Rabeprazole has the potential for various peptic diseases treatment .
    Rabeprazole Sulfide
  • HY-W103170
    1,8-Dichloroanthraquinone

    		Bacterial Others
    1,8-Dichloroanthraquinone, an anthraquinone, is an inhibitor of sulfide production by sulfate-reducing bacteria .
    1,8-Dichloroanthraquinone
  • HY-100287
    2-(E-2-decenoylamino)ethyl 2-(cyclohexylethyl) sulfide

    		Prostaglandin Receptor Phospholipase Endocrinology
    2-(E-2-decenoylamino)ethyl 2-(cyclohexylethyl) sulfide is a compound that inhibits stress-induced ulcer and low toxicity, and can maintain the content of phospholipase A2 and prostaglandin E2 in ulcerated rats induced by water immersed restrained stress.
    2-(E-2-decenoylamino)ethyl 2-(cyclohexylethyl) sulfide
  • HY-P10486
    AIP-II

    		Bacterial Infection
    AIP-II is a macrocyclic peptide signaling molecule used for quorum sensing, which can be produced be Staphylococcus aureus. AIP-II binds to AgrC-II receptor, regulates the virulence gene expression in Staphylococcus aureus. AIP-II is an antagonist for AgrC-I receptor .
    AIP-II
  • HY-P2331
    Actagardin

    Antibiotic A 3802-IV-3; Gardimycin

    		 Antibiotic Infection
    Actagardin is a tetracyclic lantibiotic produced by several species of Actinoplanes. It is composed of macrocyclic rings formed by thioether bridges. Actagardin preferably targets Gram-positive bacteria, inhibiting the synthesis of peptidoglycan.
    Actagardin
  • HY-P2031
    Phallacidin

    		Arp2/3 Complex Others
    Phallacidin is a member of the phallotoxin family of mushroom toxins. Phallacidin binds F-actin .
    Phallacidin
  • HY-W196803
    Dipropyl disulfide

    Propyl Disulfide; DPDS

    		 Cytochrome P450 Others
    Dipropyl disulfide is oxidized to dipropyl thiosulfinate (DPDSO) by rat microsomes. Both flavincontaining monooxygenases (FMO) and cytochrome P450 enzymes (CYPs) are involved in dipropyl disulfide oxidation. Dipropyl disulfide forms two metabolites: propylglutathione sulfide conjugate and propylthiol .
    Dipropyl disulfide
  • HY-P0028
    Phalloidin
    Maximum Cited Publications
    15 Publications Verification

    		 Fluorescent Dye Others
    Phalloidin is a mushroom-derived toxin which can be used to label F-actin of the cytoskeleton with fluorochrome .
    Phalloidin
  • HY-P3143
    BMSpep-57

    		PD-1/PD-L1 Cancer
    BMSpep-57 is a potent and competitive macrocyclic peptide inhibitor of PD-1/PD-L1 interaction with an IC50 of 7.68 nM. BMSpep-57 binds to PD-L1 with Kds of 19 nM and 19.88 nM in MST and SPR assays, respectively. BMSpep-57 facilitates T cell function by in creasing IL-2 production in PBMCs .
    BMSpep-57
  • HY-P3143A
    BMSpep-57 hydrochloride

    		PD-1/PD-L1 Cancer
    BMSpep-57 hydrochloride is a potent and competitive macrocyclic peptide inhibitor of PD-1/PD-L1 interaction with an IC50 of 7.68 nM. BMSpep-57 hydrochloride binds to PD-L1 with Kds of 19 nM and 19.88 nM in MST and SPR assays, respectively. BMSpep-57 hydrochloride facilitates T cell function by in creasing IL-2 production in PBMCs .
    BMSpep-57 hydrochloride
  • HY-D1275
    CAY10731

    		Fluorescent Dye Others
    CAY10731 (compound 3) is a highly selective fluorescent probe for detection of hydrogen sulfide (H2S). CAY10731 is used to monitor exo- and endogenous H2S in both cancer and normal cells. CAY10731 is applied for imaging of H2S in living tissues at variable depths and in nematodes .
    CAY10731
  • HY-119323
    7-Azido-4-methylcoumarin

    		Fluorescent Dye Others
    7-Azido-4-methylcoumarin is a fluorescent hydrogen sulfide (H2S) probe. 7-Azido-4-methylcoumarin serves as a highly sensitive assay for cystathionine β-synthase activity . It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
    7-Azido-4-methylcoumarin
  • HY-P0041A
    F992 TFA

    		Vasopressin Receptor Neurological Disease
    F992 TFA is an antidiuretic peptide and vasopressin (antidiuretic hormone) analogue .
    F992 TFA
  • HY-P0041
    F992

    		Vasopressin Receptor Neurological Disease
    F992 is an antidiuretic peptide and vasopressin (antidiuretic hormone) analogue .
    F992
  • HY-126124
    AP39
    5 Publications Verification

    		 Reactive Oxygen Species Cardiovascular Disease Neurological Disease
    AP39 is a triphenylphosphonium derivatised anethole dithiolethione and mitochondria-targeting hydrogen sulfide (H2S) donor. AP39 increases intracellular H2S levels. AP39 exerts cytoprotective effects and maintains mitochondrial DNA integrity under oxidative stress conditions. AP39 protects against myocardial reperfusion injury in mice model and has the potential for Alzheimer's disease research .
    AP39
  • HY-B1821
    Zinc sulfide

    		Biochemical Assay Reagents Others
    Zinc monosulfide is a biological molecule.
    Zinc sulfide
  • HY-P10964
    Tezusomant

    		GHSR Endocrinology
    Tezusomant is a growth hormone receptor antagonist. Tezusomant is promising for research of diseases such as acromegaly caused by excessive growth hormone secretion .
    Tezusomant
  • HY-144439
    HTS07545

    		Mitochondrial Metabolism Cardiovascular Disease
    HTS07545 is a potent sulfide:quinone oxidoreductase (SQOR) inhibitor with an IC50 of 30 nM. HTS07545 decrease the rate of breakdown of hydrogen sulfide (H2S). HTS07545 can be used for heart failure research .
    HTS07545
  • HY-B0973
    Dibenzothiophene

    DBT; Diphenylene sulfide

    		 Cytochrome P450 Aryl Hydrocarbon Receptor Metabolic Disease
    Dibenzothiophene is an orally active and a noncompetitive CYP1A inhibitor. Dibenzothiophene inhibits CYP1A-mediated EROD activity with a Km of 0.592 μM. Dibenzothiophene interacts with the AHR pathway. Dibenzothiophene enhances the embryotoxicity of β-naphthoflavone (HY-114740). Dibenzothiophene shows acute toxicity in mice. Dibenzothiophene is mainly used for the study of the mechanism of developmental toxicity in organisms .
    Dibenzothiophene
  • HY-123615
    SPD-2

    		Endogenous Metabolite Cardiovascular Disease Inflammation/Immunology
    SPD-2 is a photo-controlled hydrogen sulfide (H2S) donor that can generate hydrogen sulfide (H2S) upon UVA irradiation (325-385 nm). SPD-2 enables photo-controlled, site-specific H2S release in living cells .
    SPD-2
  • HY-P2995
    Hemoglobin

    		Biochemical Assay Reagents Heme Oxygenase (HO) Others
    Hemoglobin is a iron-containing protein in red blood cells with oxygen binding properties. Hemoglobin is an inducer of HO-1. Hemoglobin consits of heme, which binds to oxygen. Hemoglobin also transports other gases, such as carbon dioxide, nitric oxide, hydrogen sulfide and sulfide. Hemoglobin absorbs unneeded oxygen in tissues, as an antioxidant .
    Hemoglobin
  • HY-W143071S
    1-(Methylthio)-pentane-d3

    		Isotope-Labeled Compounds Others
    1-(Methylthio)-pentane-d3 is the deuterium labeled Amyl methyl sulfide (HY-W143071) .
    1-(Methylthio)-pentane-d3
  • HY-P2995A
    Hemoglobin porcine

    		Biochemical Assay Reagents Others
    Hemoglobin porcine is an iron-containing protein in red blood cells that has oxygen-binding properties. Hemoglobin porcine is a HO-1 inducer. Hemoglobin porcine is composed of heme, which can bind to oxygen. Hemoglobin porcine also transports other gases such as carbon dioxide, nitric oxide, hydrogen sulfide, and sulfide. Hemoglobin porcine absorbs oxygen that is not needed in tissues and acts as an antioxidant .
    Hemoglobin porcine
  • HY-B0973R
    Dibenzothiophene (Standard)

    DBT (Standard); Diphenylene sulfide (Standard)

    		 Cytochrome P450 Aryl Hydrocarbon Receptor Metabolic Disease
    Dibenzothiophene (Standard) is the analytical standard of Dibenzothiophene (HY-B0973). This product is intended for research and analytical applications. Dibenzothiophene is an orally active and a noncompetitive CYP1A inhibitor. Dibenzothiophene inhibits CYP1A-mediated EROD activity with Km of 0.592 μM. Dibenzothiophene interacts with the AHR pathway. Dibenzothiophene enhances the embryotoxicity of β-naphthoflavone (HY-114740). Dibenzothiophene shows acute toxicity in mice. Dibenzothiophene is mainly used for the study of the mechanism of developmental toxicity in organisms .
    Dibenzothiophene (Standard)
  • HY-W110707
    Cetylamine

    Hexadecylamine

    		 Biochemical Assay Reagents Cancer
    Cetylamine (Hexadecylamine) denatures proteins faster and prevents flocculation. Cetylamine can cap zinc sulfide nanoparticles and is used in cancer research .
    Cetylamine
  • HY-E70078
    Cystathionine β-synthase

    		Biochemical Assay Reagents Others
    Cystathionine β-synthase is an enzyme that catalyzes the condensation of serine and homocysteine to water and cystathionine. Cystathionine β-synthase is a prominent enzyme for the production of hydrogen sulfide (H2S) .
    Cystathionine β-synthase
  • HY-160240
    HPI

    		Fluorescent Dye Others Cancer
    HPI is a HS - fluorescent probe (Ex/Em=280/410 nm). HPI can be used to detect the HS - form of hydrogen sulfide (H2S) gas in environmental water samples .
    HPI
  • HY-109582
    ADT-OH
    2 Publications Verification

    5-(4-Hydroxyphenyl)-3H-1,2-dithiole-3-thione; ACS 1

    		 Apoptosis FAK Cancer
    ADT-OH is a hydrogen sulfide-releasing donor. ADT-OH induces apoptosis and upregulates FADD. ADT-OH inhibits FAK/Paxillin. ADT-OH has the potential for the research of cancer diseases .
    ADT-OH
  • HY-P1607
    Nisin
    2 Publications Verification

    		 Bacterial Antibiotic Infection Inflammation/Immunology
    Nisin is a bacteriocin produced by a group of Gram-positive bacteria that belongs to Lactococcus and Streptococcus species. Nisin has antibacterial and anti-inflammatory activity .
    Nisin
  • HY-141552
    FC9402
    1 Publications Verification

    		 Mitochondrial Metabolism Cardiovascular Disease
    FC9402 is a potent and selective sulfide quinone oxidoreductase (SQOR) inhibitor extracted from patent WO 2020/146636 A1. FC9402 attenuates TAC-induced cardiomyocyte hypertrophy and left ventricle (LV) fibrosis. FC9402 can be used for cardiovascular regulation .
    FC9402
  • HY-120425
    Ethiprole

    		Insecticide Infection
    Ethiprole is an insecticide.Metabolic sulfones are produced faster than Fipronil (HY-B0822) in CYP3A4-expressing cells and in vivo in mouse brain and liver.Ethiprole's sulfide, sulfoxide, sulfone and desulfinyl derivatives have better biological activity .
    Ethiprole
  • HY-121955
    FW1256
    1 Publications Verification

    		 NF-κB Apoptosis Cardiovascular Disease Inflammation/Immunology Cancer
    FW1256 is a phenyl analogue and a slow-releasing hydrogen sulfide (H2S) donor. FW1256 inhibits NF-κB activity and induces cell apoptosis. FW1256 exerts potent anti-inflammatory effects and has the potential for cancer and cardiovascular disease treatment .
    FW1256

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