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spinalized cats

" in MedChemExpress (MCE) Product Catalog:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-B1833
    Afloqualone

    HQ-495

    		 GABA Receptor Neurological Disease
    Afloqualone (HQ-495) is an orally active central muscle relaxant and antivertiginous agent that can increase the sensitivity of GABA receptors in neurons of the lateral vestibular nucleus. Afloqualone (HQ-495) can be used in the research of low back pain and neck-arm-shoulder syndrome .
    Afloqualone
  • HY-B0194
    Tizanidine

    		Adrenergic Receptor Neurological Disease Endocrinology Cancer
    Tizanidine is an orally active, imidazoline central α2-adrenoceptor agonist (IC50 = 6.9 nmol), which can be used to manage spasticity secondary to conditions such as multiple sclerosis (MS), stroke, and spinal cord injury (SCI). Tizanidine is a centrally acting skeletal muscle relaxant. Tizanidine reduces the release of the excitatory amino acids glutamate and aspartate from the presynaptic terminal of spinal interneurons. Tizanidine reduces tonic stretch reflexes and polysynaptic reflex activity in spinal transected cat model. Tizanidine can decrease blood pressure and heart rate in animal models. Tizanidine possesses antinociceptive activity and inhibits gastrointestinal (GI) transit .
    Tizanidine
  • HY-B0194R
    Tizanidine (Standard)

    		Reference Standards Adrenergic Receptor Neurological Disease Endocrinology Cancer
    Tizanidine (Standard) is the analytical standard of Tizanidine. This product is intended for research and analytical applications. Tizanidine is an orally active, imidazoline central α2-adrenoceptor agonist (IC50 = 6.9 nmol), which can be used to manage spasticity secondary to conditions such as multiple sclerosis (MS), stroke, and spinal cord injury (SCI). Tizanidine is a centrally acting skeletal muscle relaxant. Tizanidine reduces the release of the excitatory amino acids glutamate and aspartate from the presynaptic terminal of spinal interneurons. Tizanidine reduces tonic stretch reflexes and polysynaptic reflex activity in spinal transected cat model. Tizanidine can decrease blood pressure and heart rate in animal models. Tizanidine possesses antinociceptive activity and inhibits gastrointestinal (GI) transit .
    Tizanidine (Standard)

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