1. Search Result
Search Result
Results for "

retinol

" in MedChemExpress (MCE) Product Catalog:

32

Inhibitors & Agonists

11

Natural
Products

14

Recombinant Proteins

5

Isotope-Labeled Compounds

3

Antibodies

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-N0679
    Retinyl acetate
    2 Publications Verification

    retinol acetate; Vitamin A acetate

    Others Cancer
    Retinyl acetate is a synthetic acetate ester form derived from retinol and has potential antineoplastic and chemo preventive activities .
    Retinyl acetate
  • HY-B1384

    Vitamin A palmitate; retinol palmitate

    Endogenous Metabolite Others
    Retinyl palmitate is an ester of Retinol and is the major form of vitamin A found in the epidermis. Retinyl palmitate has been widely used in pharmaceutical and cosmetic formulations.
    Retinyl palmitate
  • HY-N0679S4

    retinol acetate-d4; Vitamin A acetate-d4

    Isotope-Labeled Compounds Cancer
    Retinyl acetate-d4 is the deuterium labeled Retinyl acetate . Retinyl acetate is a synthetic acetate ester form derived from retinol and has potential antineoplastic and chemo preventive activities .
    Retinyl acetate-d4
  • HY-W654334

    Isotope-Labeled Compounds Endogenous Metabolite Inflammation/Immunology
    9-cis-Retinol-d5 is deuterium labeled 9-cis Retinol. 9-cis Retinol is a precursor of 9-cis-Retinal (HY-W009310). 9-cis Retinol can inhibit 9-cis-Retinoic acid (HY-15128) synthesis in Hep G2 cells .
    9-cis-Retinol-d5
  • HY-W587806

    Endogenous Metabolite Inflammation/Immunology
    9-cis Retinol is a precursor of 9-cis-Retinal (HY-W009310). 9-cis Retinol can inhibit 9-cis-Retinoic acid (HY-15128) synthesis in Hep G2 cells .
    9-cis Retinol
  • HY-N0679R

    retinol acetate (Standard); Vitamin A acetate (Standard)

    Reference Standards Others Cancer
    Retinyl acetate (Standard) is the analytical standard of Retinyl acetate. This product is intended for research and analytical applications. Retinyl acetate is a synthetic acetate ester form derived from retinol and has potential antineoplastic and chemo preventive activities .
    Retinyl acetate (Standard)
  • HY-B1384R

    Vitamin A palmitate (Standard); retinol palmitate (Standard)

    Endogenous Metabolite Others
    Retinyl palmitate (Standard) is the analytical standard of Retinyl palmitate. This product is intended for research and analytical applications. Retinyl palmitate is an ester of Retinol and is the major form of vitamin A found in the epidermis. Retinyl palmitate has been widely used in pharmaceutical and cosmetic formulations.
    Retinyl palmitate (Standard)
  • HY-N0679S

    ALK-001; retinol acetate-d3; Vitamin A acetate-d3

    Isotope-Labeled Compounds Metabolic Disease
    Retinyl acetate-d3 (ALK-001) is a deuterated Vitamin A. Retinyl acetate-d3 can be used for research of geographic atrophy (GA) secondary to age-related macular degeneration (AMD) .
    Retinyl acetate-d3
  • HY-W587807

    Endogenous Metabolite Neurological Disease
    11-cis-Retinol, a form of retinol, can bind to RDH5. 11-cis-Retinol promote dark adaptation and recovery of photoresponsiveness of red cones but not of red rods .
    11-cis-Retinol
  • HY-169085

    Acyltransferase Metabolic Disease
    LRAT-IN-1 (compound 1) is a retinol acyltransferase (LRAT) inhibitor (IC50=21.1 μM). LRAT-IN-1 provides anti-aging effects by inhibiting the esterification of retinol to form retinol esters, increasing the available retinol in the skin. Research on LRAT-IN-1 as an anti-aging ingredient in cosmetics .
    LRAT-IN-1
  • HY-142107S

    Isotope-Labeled Compounds Others
    9-cis,13-cis-Retinol-d5 is the deuterium labeled 9-cis,13-cis-Retinol .
    9-cis,13-cis-Retinol-d5
  • HY-16760

    9-cis-Vitamin A acetate; Zuretinol acetate

    Others Others
    9-cis-Retinol acetate is a retinal derivative.
    9-cis-Retinol acetate
  • HY-N7495R

    Anhydrovitamin A (Standard)

    Reference Standards Drug Metabolite Metabolic Disease
    all-trans-Anhydro Retinol (Standard) (Anhydrovitamin A (Standard)) is the analytical standard of all-trans-Anhydro Retinol (HY-N7495). This product is intended for research and analytical applications. all-trans-Anhydro Retinol (Anhydrovitamin A) is an orally active degradation product formed by the dehydration of vitamin A alcohol and its esters under conditions such as acidic catalysis or hydroxylic solvents, with a biological activity only 0.4% of that of Vitamin A (HY-B1342). In rats, all-trans-Anhydro Retinol can be metabolized into hydroxy derivatives and their esters, but it cannot be converted into Vitamin A (HY-B1342) and has a low storage capacity in the body .
    all-trans-Anhydro Retinol (Standard)
  • HY-N7495

    Anhydrovitamin A

    Drug Metabolite Metabolic Disease
    all-trans-Anhydro Retinol (Anhydrovitamin A) is an orally active degradation product formed by the dehydration of vitamin A alcohol and its esters under conditions such as acidic catalysis or hydroxylic solvents, with a biological activity only 0.4% of that of Vitamin A (HY-B1342). In rats, all-trans-Anhydro Retinol can be metabolized into hydroxy derivatives and their esters, but it cannot be converted into Vitamin A (HY-B1342) and has a low storage capacity in the body .
    all-trans-Anhydro Retinol
  • HY-16760S

    9-cis-Vitamin A acetate-d5; Zuretinol acetate-d5

    Isotope-Labeled Compounds Others
    9-cis-Retinol acetate-d5 is the deuterium labeled 9-cis-Retinol acetate. 9-cis-Retinol acetate is a retinal derivative .
    9-cis-Retinol acetate-d5
  • HY-147251

    Drug Derivative Others
    SRI 6409-94 is an orally active Ro 13-6298 analogue that is teratogenic. SRI 6409-94 serves as a molecular tool to study the effect of the three-dimensional configuration of retinol on teratogenic activity .
    SRI 6409-94
  • HY-172232

    Lipocalin Family Neurological Disease
    STG-001 is a retinol binding protein 4 (RBP4) antagonist. STG-001 inhibits RBP4 to reduce the synthesis of retinal and diretinol, thereby preventing photoreceptor degeneration. STG-001 can be used in the study of sexually precocious nephropathy (STGD) .
    STG-001
  • HY-145806

    13-cis-retinol acetate; 13-cis-Vitamin A acetate

    Endogenous Metabolite Endocrinology
    13-cis-Retinyl acetate (13-cis-Retinol acetate; 13-cis-Vitamin A acetate) is a 13-cis isomer formed by Retinyl acetate. 13-cis-Retinyl acetate is an active metabolite of vitamin A .
    13-cis-Retinyl acetate
  • HY-W739769

    13,14-Dihydroretinol

    Endogenous Metabolite Others
    all-trans-13,14-Dihydroretinol is a metabolite of all-trans-retinol (HY-B1342). all-trans-retinol is catalyzed by retinol saturase to form all-trans-13,14-Dihydroretinol .
    all-trans-13,14-Dihydroretinol
  • HY-139394

    Lipocalin Family Metabolic Disease
    Arachidonoyl-1-thio-glycerol (Compound 5) is an nonretinoid ligand lipid that can interact with cellular retinol binding protein 2 (CRBP2) .
    Arachidonoyl-1-thio-glycerol
  • HY-115731

    Desmethyltocopherol; DL-Tocol; rac-Tocol

    Endogenous Metabolite Metabolic Disease
    (±)-Tocol is a synthetic vitamin E derivative.nlike (±)-α-tocopherol, (±)-tocol does not suppress retinol-induced erythrocyte hemolysis or increase microviscosity of rat liver phosphatidylcholine (PC) liposomes.
    Tocol
  • HY-107633
    A 1120
    1 Publications Verification

    Transthyretin (TTR) Metabolic Disease
    A 1120 is a high-affinity nonretinoid retinol-binding protein 4 (RBP4) antagonist with a Ki value of 8.3 nM. A 1120 disrupts the interaction between RBP4 and its binding partner transthyretin .
    A 1120
  • HY-B1342

    Vitamin A1; all-trans-retinol

    Endogenous Metabolite Metabolic Disease
    Vitamin A (Vitamin A1) is an endogenous metabolite.
    Vitamin A
  • HY-19720

    ACU-4429

    RPE65 Metabolic Disease
    Emixustat is an orally active RPE65 inhibitor with an IC50 value of 4.4 nM. Emixustat is also a visual cycle modulator, capable of regulating visual cycle activity by inhibiting retinol isomerization, and holds potential for studying vision disorders such as age-related macular degeneration (AMD) .
    Emixustat
  • HY-W011094
    Win 18446
    1 Publications Verification

    Aldehyde Dehydrogenase (ALDH) Endocrinology
    Win 18446 is an orally active testes-specific enzyme ALDH1a2 inhibitor, with an IC50 of 0.3 μM. Win 18446 reversibly inhibits spermatogenesis in many species and inhibits Retinoic acid (HY-14649) biosynthesis from Retinol (HY-B1342) within the testes .
    Win 18446
  • HY-19720A

    ACU-4429 hydrochloride

    Others Metabolic Disease
    Emixustat (ACU-4429) hydrochloride is an orally active RPE65 inhibitor with an IC50 value of 4.4 nM. Emixustat hydrochloride is also a visual cycle modulator, capable of regulating visual cycle activity by inhibiting retinol isomerization, and holds potential for studying vision disorders such as age-related macular degeneration (AMD) .
    Emixustat hydrochloride
  • HY-B1342A

    13-cis-Vitamin A1; 13-cis-retinol

    Drug Isomer Drug Metabolite Metabolic Disease
    13-cis-Vitamin A (13-cis-Vitamin A1) is the 13-cis-isomer of Vitamin A (HY-B1342), which is an active metabolite found in butter .
    13-cis-Vitamin A
  • HY-147366

    Lipocalin Family Metabolic Disease
    RBP4 ligand-1 is a non-retinoid ligands for (RBP4) retinol-binding protein 4. The hRBP4SPA IC50 and RBP4-TTR FRET IC50 values are 0.23±0.11 and 0.13±0.12 μM in the radioligand binding assay and FRET assay, respectively .
    RBP4 ligand-1
  • HY-143793

    Lipocalin Family Metabolic Disease
    RBP4 inhibitor 1 (compound 43b) is a potent and orally active retinol-binding protein 4 (RBP4) inhibitor with IC50s of 28 nM and 110 nM for human and mouse RBP4. RBP4 inhibitor 1 has a potent and long-lasting blood RBP4-level-reducing effect in mice .
    RBP4 inhibitor 1
  • HY-W004500
    All-trans-retinal
    1 Publications Verification

    Endogenous Metabolite Apoptosis Metabolic Disease
    All-trans-retinal is an vitamin A metabolite in the retina, and is produced following photo-isomerization of the visual chromophore 11-cis-Retinal. All-trans-retinal is cleared from photoreceptors by ATP-binding cassette transporter (ABCA4) and all-trans-retinol dehydrogenase (RDH). All-trans-retinal induces Bax activation via DNA damage to mediate retinal cell apoptosis .
    All-trans-retinal
  • HY-W009310

    Endogenous Metabolite Organoid Others
    9-cis-Retinal is a natural retinoid. Dietary 9-cis-β-carotene generates 9-cis-retinoids via cleavage into 9-cis-retinal. 9-cis Retinal binds to cellular retinol-binding protein-I (CRBP-I) and CRBP-II with Kds of 8 nM and 5 nM, respectively. 9-cis-Retinal expedites differentiation and maturation of rod photoreceptors in retinal organoids .
    9-cis-Retinal
  • HY-125904

    RAR/RXR Neurological Disease Inflammation/Immunology Cancer
    4-Hydroxyretinoic acid (4-HRA) is a naturally occurring retinoid derivative with diverse biological effects. 4-Hydroxyretinoic acid is formed from retinol catalyzed by cytochrome P-450 isozyme(s), and is mainly metabolized by the liver in the body. 4-Hydroxyretinoic acid also serves as the substrate for human liver microsomal UDP-glucuronosyltransferase(s) and recombinant UGT2B7. 4-Hydroxyretinoic acid regulates gene expression and cell differentiation via binding to nuclear receptor RAR (Retinoic Acid Receptor), and activates RARs and RXR-alpha, to induce cancer cell apoptosis. In addition, 4-Hydroxyretinoic acid is also involved in various physiological processes such as immune regulation, neuroprotection, and anti-oxidation .
    4-Hydroxyretinoic acid

Inquiry Online

Your information is safe with us. * Required Fields.

Salutation

 

Country or Region *

Applicant Name *

 

Organization Name *

Department *

     

Email Address *

 

Product Name *

Cat. No.

 

Requested quantity *

Phone Number *

     

Remarks

Inquiry Online

Inquiry Information

Product Name:
Cat. No.:
Quantity:
MCE Japan Authorized Agent: