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Results for "

polyketide metabolite

" in MedChemExpress (MCE) Product Catalog:

11

Inhibitors & Agonists

9

Natural
Products

Targets Recommended:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-N10293
    Monaschromone

    		Fungal Endogenous Metabolite Infection
    Monaschromone, a polyketide metabolite, significantly inhibits the growth of B. cinerea, A. solani, M. oryzae, and G. saubinettii, with the MIC values ranging from 6.25 to 12.5 μM .
    Monaschromone
  • HY-N16423
    Metenaticin A

    		Endogenous Metabolite Others
    Metenaticin A (Compound 8), a polyketide, is a microbial secondary metabolite. Metenaticin A can be isolated from Streptomyces violaceoruber TU22 .
    Metenaticin A
  • HY-N16443
    Sporminarin A

    		Endogenous Metabolite Fungal Bacterial Infection
    Sporminarin A (Compound 1), a polyketide, is a microbial secondary metabolite. Sporminarin A can be isolated from the Sporormiella minimoides. Sporminarin A has significant antifungal activity against Aspergillus flavus with an MIC50 of 25  μg/mL. Sporminarin A also has antibacterial activity against Staphylococcus aureus (ATCC 29213) and Candida albicans (ATCC 14053) .
    Sporminarin A
  • HY-N14162
    Dihydroabikoviromycin

    		Antibiotic Bacterial Infection Inflammation/Immunology
    Dihydroabikoviromycin, a secondary metabolite of Streptomyces anulatus, is a polyketide synthase inhibitor .
    Dihydroabikoviromycin
  • HY-N14066
    Ascochitine

    		Fungal Infection
    Ascochitine, a polyketide-derived secondary metabolite, is a selective antifungal agent. Ascochitine exhibits broad-spectrum phytotoxicity and antimicrobial activities .
    Ascochitine
  • HY-N10292
    Chaetosemin J

    		Fungal Endogenous Metabolite Infection
    Chaetosemin J, an antifungal metabolite, exhibits inhibitory activity against plant pathogenic fungi Botrytis cinerea, Alternaria solani, Magnaporthe oryzae, and Gibberella saubinettii, with MIC values ranging from 12.5-25 μM .
    Chaetosemin J
  • HY-N16429
    Neosartoricin D

    		Endogenous Metabolite Others
    Neosartoricin D, a polyketide, is a microbial secondary metabolite. Neosartoricin D can be isolated from the cultural of Aspergillus nidulans. Neosartoricin D is an analog of Neosartoricin B (HY-N10311). Neosartoricin B is the secondary metabolite, which can be produced by Aspergillus nidulans. Neosartoricin B may regulate immunomodulatory effects with the host during infection and colonization by pathogenic fungi .
    Neosartoricin D
  • HY-117760
    Spirolaxine

    		Bacterial Endogenous Metabolite Infection
    Spirolaxine is a plant growth inhibitor and possess significant anti-Helicobacter pylori activity. Spirolaxine exhibits cholesterol-lowering activity .
    Spirolaxine
  • HY-121003
    Aspyrone

    		Fungal Parasite Infection
    Aspyrone is a polyketide fungal metabolite that has been found in Aspergillus and has diverse biological activities. It is active against a panel of 13 fungi when used at a concentration of 20 μg/mL and a panel of 21 bacteria in a disc assay when used at a concentration of 100 μg per disc.1 Aspyrone (10-1,000 mg/L) is nematocidal against P. penetrans.
    Aspyrone
  • HY-N12390
    Alternaphenol B2

    		Isocitrate Dehydrogenase (IDH) Cancer
    Alternaphenol B2 is a selective IDH1 inhibitor from the coral-derived fungus Parengyodontium album SCSIO SX7W11. Alternaphenol B2 shows inhibitory activity against isocitrate dehydrogenase mutant R132H (IDH1m), with IC50 values of 41.9 μM .
    Alternaphenol B2
  • HY-W781265
    BE 24566B

    L-755,805

    		 Endothelin Receptor Bacterial Infection
    BE 24566B is a polyketide fungal metabolite originally isolated from S. violaceusniger. It is active against B. subtilis, B. cereus, S. aureus, M. luteus, E. faecalis, and S. thermophilus (MICs=1.56, 1.56, 1.56, 1.56, 3.13, and 3.13 μg/mL, respectively). BE 24566B is an endothelin (ET) receptor antagonist (IC50s=11 and 3.9 μM for ETA and ETB receptors, respectively).
    BE 24566B

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