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Results for "

platinum compound

" in MedChemExpress (MCE) Product Catalog:

13

Inhibitors & Agonists

4

Biochemical Assay Reagents

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-W034985
    Tetrakis(triphenylphosphine)platinum

    Tetrakis(triphenylphosphine)platinum(0)

    		 Biochemical Assay Reagents Others
    Tetrakis(triphenylphosphine)platinum is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
    Tetrakis(triphenylphosphine)platinum
  • HY-W009311
    Thiomichler's ketone

    4,4'-Bis(dimethylamino)thiobenzophenone

    		 Biochemical Assay Reagents Others
    Thiomichler's ketone (4,4'-Bis(dimethylamino)thiobenzophenone) can be used as a photometric reagent for the determination of gold, palladium, platinum, mercury, silver, and copper. Thiomichler's ketone is a kind of biological materials or organic compounds that are widely used in life science research .
    Thiomichler's ketone
  • HY-Y0091
    Xantphos

    9,9-Dimethyl-4,5-bis(diphenylphosphino)xanthene

    		 Biochemical Assay Reagents Others
    Xantphos (9,9-Dimethyl-4,5-bis(diphenylphosphino)xanthene) is a bisphosphine ligand. Xantphos coordinates to metals in either cis or trans chelation mode. Xantphos acts as a key ligand in palladium or platinum catalyzed reactions. Xantphos can be used in the construction of heterocyclic compounds in organic synthesis .
    Xantphos
  • HY-151883
    APE1-IN-2

    		Apoptosis MDM-2/p53 Cancer
    APE1-IN-2 (compound AP1) is a Pt(IV) proagent, targeting a critical BER protein, apurinic/apyrimidinic endonuclease 1 (APE1). APE1-IN-2 shows anticancer activity. APE1-IN-2 induces intracellular accumulation of platinum and activates DNA damage response and apoptosis signals .
    APE1-IN-2
  • HY-W096169D
    Platinum

    		Biochemical Assay Reagents Cancer
    Platinum is a metallic compound that can be used in cancer research .
    Platinum
  • HY-176149
    Fluoxetine-Conjugated Platinum(IV) prodrug-1

    		CaMK MMP AMPK Apoptosis Autophagy Cancer
    Fluoxetine-Conjugated Platinum(IV) prodrug-1 (Compound 8) is an eEF2K inhibitor. Fluoxetine-Conjugated Platinum(IV) prodrug-1 inhibits cancer cell proliferation, induces DNA damage, cell cycle arrest at S phase and apoptosis. Fluoxetine-Conjugated Platinum(IV) prodrug-1 induces ROS accumulation and mitochondrial dysfunction. Fluoxetine-Conjugated Platinum(IV) prodrug-1 inhibits TNBC cell migration and invasion by inhibiting MMP-2 activity. Fluoxetine-Conjugated Platinum(IV) prodrug-1 induces autophagy in TNBC cells by activating AMPK. Fluoxetine-Conjugated Platinum(IV) prodrug-1 has antitumor activity and activates immunosuppression in the 4T1-Luc mouse model. Fluoxetine-Conjugated Platinum(IV) prodrug-1 can be used in triple-negative breast cancer (TNBC) research .
    Fluoxetine-Conjugated Platinum(IV) prodrug-1
  • HY-105530
    Zeniplatin

    CL 286558

    		 Biochemical Assay Reagents Cancer
    Zeniplatin is a third-generation, water-soluble platinum compound that has shown broad antitumor activity. Zeniplatin can be used for cancer research .
    Zeniplatin
  • HY-129909
    Anticancer agent 173

    		Apoptosis Infection Cancer
    Anticancer agent 173 (compound 19) is a potent thioxodihydroquinazolinone analogs when combined with platinum drugs in inducing apoptotic cancer cells death .
    Anticancer agent 173
  • HY-157222
    Antitumor agent-125

    		Apoptosis Ferroptosis Cancer
    Antitumor agent-125 (compound 17A) is a novel platinum(IV) prodrug. Antitumor agent-125 can activate the mitochondrion-dependent apoptosis pathway. Antitumor agent-125 induces ferroptosis in HCT-116/OXA .
    Antitumor agent-125
  • HY-125010
    Dicycloplatin

    		DNA/RNA Synthesis Apoptosis Cancer
    Dicycloplatin is a DNA damage inducer. Dicycloplatin induces DNA damage by activating biphosphorylated checkpoint kinase 2 (CHK2), breast cancer 1 (BRCA1) and triphosphorylated p53. Dicycloplatin can induce cell cycle arrest, inhibit proliferation and lead to apoptosis in prostate cancer PC3 cells and lung cancer NCI/H446 cells. Dicycloplatin can be used in cancer researchr .
    Dicycloplatin
  • HY-155012
    Mcl-1 inhibitor 16

    		Bcl-2 Family Cancer
    Mcl-1 inhibitor 16 (Compound 9) is a mitochondrial targeting Platinum-based inhibitor of Mcl-1. Mcl-1 inhibitor 1 induces Bax/Bak-dependent apoptosis in cancer cells. Mcl-1 inhibitor 16 can be used alone or together with ABT-199 (HY-15531) and shows anti-tumor activity .
    Mcl-1 inhibitor 16
  • HY-161623
    ERCC1/XPA interaction inhibitor 1

    		DNA/RNA Synthesis Cancer
    ERCC1/XPA interaction inhibitor 1 (compound 27o) is a potent ERCC1/XPA67-80 interaction inhibitor with an EC50 value of 4.7 µM. ERCC1/XPA interaction inhibitor 1 has the potential for the research of DNA damaging agents and overcoming resistance to platinum-based chemotherapy .
    ERCC1/XPA interaction inhibitor 1
  • HY-155808
    STAT3-IN-18

    		STAT JAK Apoptosis COX Cancer
    STAT3-IN-18 (compound SPP) is a platinum (IV) complex with an axial ligand derived from sandalwood. STAT3-IN-18 inhibits the JAK2-STAT3 pathway in breast cancer (BC) cells, with anti-proliferative activity. STAT3-IN-18 activates caspase-3 and increases cleaved polyADP-ribose polymerase to induce apoptosis. STAT3-IN-18 promotes maturation and antigen presentation of dendritic cells and demonstrates safety in vivo.
    STAT3-IN-18

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