Search Result
Results for "
phytoestrogen
" in MedChemExpress (MCE) Product Catalog:
1
Biochemical Assay Reagents
| Cat. No. |
Product Name |
Target |
Research Areas |
Chemical Structure |
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- HY-N0595
-
|
Genistine; Genistoside; Genistein 7-O-β-D-glucopyranoside
|
Estrogen Receptor/ERR
Apoptosis
|
Metabolic Disease
Cancer
|
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Genistin (Genistine), an isoflavone belonging to the phytoestrogen family, is a potent anti-adipogenic and anti-lipogenic agent. Genistin attenuates cellular growth and promotes apoptotic cell death breast cancer cells through modulation of ERalpha signaling pathway .
|
-
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- HY-126109
-
|
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Estrogen Receptor/ERR
Apoptosis
|
Metabolic Disease
Endocrinology
Cancer
|
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(±)-8-Prenylnaringenin, a natural prenylated flavonoid, is a potent phytoestrogen. (±)-8-Prenylnaringenin is an orally active selective estrogen receptor modulator (SERM) (Estrogen Receptor/ERR) that inhibits ERα and ERβ with IC50s of 57 nM and 68 nM, respectively. (±)-8-Prenylnaringenin has anticancer effects, and can be used for osteoporosis research .
|
-
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- HY-N0235
-
|
(S)-(+)-Bakuchiol
|
Carboxylesterase (CES)
p38 MAPK
Autophagy
UGT
|
Infection
Metabolic Disease
Inflammation/Immunology
Cancer
|
|
Bakuchiol is a phytoestrogen that can be obtained from psoralen seeds. Bakuchiol has been proven to be a non-competitive inhibitor of multiple enzymes, including UDP-glucuronosyltransferase 2B7 (UGT2B7) and human carboxylesterase 2 (hCE2) , with IC50s values of 40.9 μM and 7.28 μM, respectively. Bakuchiol exhibits significant research and application potential in areas such as anti-inflammatory , antibacterial , antitumor therapies, as well as drug metabolism regulation.
|
-
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- HY-N1461
-
-
-
- HY-N0553
-
-
-
- HY-108052
-
|
Delphinidin 3-O-glucoside chloride; Delphinidin 3-O-β-glucoside chloride
|
EGFR
Apoptosis
Akt
|
Cardiovascular Disease
Cancer
|
|
Delphinidin 3-glucoside chloride (Delphinidin 3-O-glucoside chloride) is an active anthocyanin found in Hibiscus sabdariffa extract. Delphinidin 3-glucoside chloride induces a pro-apoptotic effect in B cell chronic lymphocytic leukaemia (B CLL) . Delphinidin 3-glucoside chloride exerts phytoestrogen activity by binding to ERβ, with an IC50 of 9.7 μM . Delphinidin-3-O-glucoside chloride inhibits EGFR with an IC50 of 2.37 µM . Delphinidin 3-glucoside chloride exhibits antitumor effects through pAKT/IRF1/HOTAIR pathway. Delphinidin 3-glucoside chloride exhibits efficacy against oxidative stress, inhibits platelet activation and endothelial dysfunction .
|
-
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- HY-N8366
-
|
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Phosphatase
|
Endocrinology
Cancer
|
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Alloisoimperatorin (Compound 5) is a phytoestrogen that can be isolated from Angelica dahurica. Alloisoimperatorin can induce alkaline phosphatase (AP) activity with an EC50 of 0.8 μg/mL. Alloisoimperatorin can be used in the study of hormone-dependent cancers and the alleviation of menopausal symptoms .
|
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- HY-N0595R
-
|
Genistine (Standard); Genistoside (Standard); Genistein 7-O-β-D-glucopyranoside (Standard)
|
Reference Standards
Estrogen Receptor/ERR
Apoptosis
|
Metabolic Disease
Cancer
|
|
Genistin (Standard) is the analytical standard of Genistin. This product is intended for research and analytical applications. Genistin (Genistine), an isoflavone belonging to the phytoestrogen family, is a potent anti-adipogenic and anti-lipogenic agent. Genistin attenuates cellular growth and promotes apoptotic cell death breast cancer cells through modulation of ERalpha signaling pathway .
|
-
-
- HY-N0235R
-
|
(S)-(+)-Bakuchiol (Standard)
|
Carboxylesterase (CES)
Reference Standards
p38 MAPK
Autophagy
UGT
|
Infection
Metabolic Disease
Inflammation/Immunology
Cancer
|
|
Bakuchiol (Standard) is the analytical standard of Bakuchiol. This product is intended for research and analytical applications. Bakuchiol is a phytoestrogen that can be obtained from psoralen seeds. Bakuchiol has been proven to be a non-competitive inhibitor of multiple enzymes, including UDP-glucuronosyltransferase 2B7 (UGT2B7) and human carboxylesterase 2 (hCE2) , with IC50s values of 40.9 μM and 7.28 μM, respectively. Bakuchiol exhibits significant research and application potential in areas such as anti-inflammatory , antibacterial , antitumor therapies, as well as drug metabolism regulation.
|
-
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- HY-129899
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-
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- HY-N4200
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-
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- HY-108052R
-
|
Delphinidin 3-O-glucoside chloride (Standard); Delphinidin 3-O-β-glucoside chloride (Standard)
|
Reference Standards
EGFR
Apoptosis
Akt
|
Cardiovascular Disease
Cancer
|
|
Delphinidin 3-glucoside (chloride) (Standard) is the analytical standard of Delphinidin 3-glucoside (chloride). This product is intended for research and analytical applications. Delphinidin 3-glucoside chloride (Delphinidin 3-O-glucoside chloride) is an active anthocyanin found in Hibiscus sabdariffa extract. Delphinidin 3-glucoside chloride induces a pro-apoptotic effect in B cell chronic lymphocytic leukaemia (B CLL) . Delphinidin 3-glucoside chloride exerts phytoestrogen activity by binding to ERβ, with an IC50 of 9.7 μM . Delphinidin-3-O-glucoside chloride inhibits EGFR with an IC50 of 2.37 µM . Delphinidin 3-glucoside chloride exhibits antitumor effects through pAKT/IRF1/HOTAIR pathway. Delphinidin 3-glucoside chloride exhibits efficacy against oxidative stress, inhibits platelet activation and endothelial dysfunction .
|
-
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- HY-W354066
-
|
|
Biochemical Assay Reagents
|
|
|
Biochanin A-7-O-β-D-glucuronide is a glucuronidated derivative of phytoestrogen, which has the ability to study the metabolic activity of phytoestrogen in the ecosystem. Biochanin A-7-O-β-D-glucuronide plays an important role in ecological research. Biochanin A-7-O-β-D-glucuronide is used to explore the interaction between plants and the environment.
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- HY-N3755
-
|
|
Estrogen Receptor/ERR
|
Cancer
|
|
Dihydroresveratrol, a potent phytoestrogen, is a hormone receptor modulator. Dihydroresveratrol exhibits proliferative effects in androgen-independent prostate and breast cancer cells at picomolar and nanomolar concentrations .
|
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- HY-N2335
-
|
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Estrogen Receptor/ERR
|
Cancer
|
|
Coumestrol, a phytoestrogen present in soybean products, exhibits activities against cancers, neurological disorders, and autoimmune diseases. It suppresses proliferation of ES2 cells with an IC50 of 50 μM.
|
-
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- HY-N6787R
-
|
Dihydrothymine (Standard)
|
Reference Standards
Endogenous Metabolite
|
Metabolic Disease
|
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Gypenoside XVII (Standard) is the analytical standard of Gypenoside XVII. This product is intended for research and analytical applications. Gypenoside XVII, a novel phytoestrogen belonging to the gypenosides, can activate estrogen receptors.
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-
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- HY-N0553R
-
-
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- HY-N0233
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Bavachin
Maximum Cited Publications
10 Publications Verification
Corylifolin
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Estrogen Receptor/ERR
|
Cancer
|
|
Bavachin, a flavonoid first isolated from seeds of P. corylifolia, acts as a phytoestrogen that activates the estrogen receptors ERα and ERβ with EC50s of 320 and 680 nM, respectively.
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- HY-N0791
-
|
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Estrogen Receptor/ERR
|
Cancer
|
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Tectoridin is a isoflavone isolated from Maackia amurensis. Tectoridin is a phytoestrogen and activates estrogen and thyroid hormone receptors. Tectoridin exerts the estrogenic effects via ER-dependent genomic pathway and GPR30-dependent nongenomic pathway .
|
-
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- HY-N2335R
-
|
|
Reference Standards
Estrogen Receptor/ERR
|
Cancer
|
|
Coumestrol (Standard) is the analytical standard of Coumestrol. This product is intended for research and analytical applications. Coumestrol, a phytoestrogen present in soybean products, exhibits activities against cancers, neurological disorders, and autoimmune diseases. It suppresses proliferation of ES2 cells with an IC50 of 50 μM.
|
-
-
- HY-N0233R
-
|
Corylifolin (Standard)
|
Reference Standards
Estrogen Receptor/ERR
|
Cancer
|
|
Bavachin (Standard) is the analytical standard of Bavachin. This product is intended for research and analytical applications. Bavachin, a flavonoid first isolated from seeds of P. corylifolia, acts as a phytoestrogen that activates the estrogen receptors ERα and ERβ with EC50s of 320 and 680 nM, respectively.
|
-
-
- HY-W006405
-
|
|
Estrogen Receptor/ERR
|
Cardiovascular Disease
Cancer
|
|
Isoflavone is an orally available bioactive component of soy phytoestrogen with lipid-lowering and antioxidant activities. Isoflavone prevents a variety of chronic diseases by regulating fatty acid oxidation in the liver and gene expression in adipose tissue. In addition, isoflavone has important value in the research of cancer and cardiovascular diseases .
|
-
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- HY-N0791R
-
|
|
Reference Standards
Estrogen Receptor/ERR
|
Cancer
|
|
Tectoridin (Standard) is the analytical standard of Tectoridin. This product is intended for research and analytical applications. Tectoridin is a isoflavone isolated from Maackia amurensis. Tectoridin is a phytoestrogen and activates estrogen and thyroid hormone receptors. Tectoridin exerts the estrogenic effects via ER-dependent genomic pathway and GPR30-dependent nongenomic pathway .
|
-
-
- HY-114367
-
|
Delphinidin 3-O-rutinoside chloride
|
Apoptosis
|
Cancer
|
|
Delphinidin 3-rutinoside chloride (Delphinidin 3-O-rutinoside chloride) is an active anthocyanin found in Solanum melongena. Delphinidin 3-rutinoside chloride induces a pro-apoptotic effect in B cell chronic lymphocytic leukaemia (B CLL) . Delphinidin 3-rutinoside chloride exerts phytoestrogen activity by binding to ERβ, with an IC50 of 2.3 μM .
|
-
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- HY-W006405R
-
|
|
Reference Standards
Others
|
Cardiovascular Disease
Cancer
|
|
Isoflavone (Standard) is the analytical standard of Isoflavone. This product is intended for research and analytical applications. Isoflavone is an orally available bioactive component of soy phytoestrogen with lipid-lowering and antioxidant activities. Isoflavone prevents a variety of chronic diseases by regulating fatty acid oxidation in the liver and gene expression in adipose tissue. In addition, isoflavone has important value in the research of cancer and cardiovascular diseases .
|
-
-
- HY-B2171AR
-
|
Carminomycin hydrochloride (Standard); Carminomicin I hydrochloride (Standard)
|
Reference Standards
Apoptosis
|
Infection
Cancer
|
|
Isoflavone (Standard) is the analytical standard of Isoflavone. This product is intended for research and analytical applications. Isoflavone is an orally available bioactive component of soy phytoestrogen with lipid-lowering and antioxidant activities. Isoflavone prevents a variety of chronic diseases by regulating fatty acid oxidation in the liver and gene expression in adipose tissue. In addition, isoflavone has important value in the research of cancer and cardiovascular diseases .
|
-
-
- HY-131586
-
|
Resogalangin
|
17β-HSD
Estrogen Receptor/ERR
Aldose Reductase
|
Endocrinology
Cancer
|
|
3,7-Dihydroxyflavone (Resogalangin) is a flavonoid phytoestrogen, which can be isolated from Adenophora species. 3,7-Dihydroxyflavone is a modulator of estrogen receptors and an inhibitor of human progesterone metabolizing enzyme AKR1C1 and fungal 17β-hydroxysteroid dehydrogenase and a redox inhibitor (IC50=0.6 and 6.0 μM, respectively). 3,7-Dihydroxyflavone is a fluorescent binding substrate for human serum albumin (HSA) with excitation wavelengths of 370 nm (pH 7.4) and 350 nm (pH 3.5), respectively, and emission wavelength of 515 nm .
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-
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- HY-113382R
-
|
1-Methylhydantoin (Standard)
|
Reference Standards
Endogenous Metabolite
|
Others
|
|
Delphinidin 3-glucoside (chloride) (Standard) is the analytical standard of Delphinidin 3-glucoside (chloride). This product is intended for research and analytical applications. Delphinidin 3-glucoside chloride (Delphinidin 3-O-glucoside chloride) is an active anthocyanin found in Hibiscus sabdariffa extract. Delphinidin 3-glucoside chloride induces a pro-apoptotic effect in B cell chronic lymphocytic leukaemia (B CLL) . Delphinidin 3-glucoside chloride exerts phytoestrogen activity by binding to ERβ, with an IC50 of 9.7 μM . Delphinidin-3-O-glucoside chloride inhibits EGFR with an IC50 of 2.37 µM . Delphinidin 3-glucoside chloride exhibits antitumor effects through pAKT/IRF1/HOTAIR pathway. Delphinidin 3-glucoside chloride exhibits efficacy against oxidative stress, inhibits platelet activation and endothelial dysfunction .
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- HY-119539
-
|
|
Phosphatase
|
Endocrinology
Cancer
|
|
Limocitrin is a natural product that can be isolated from the buds of P. acerifolia and P. orientalis. Limocitrin suppresses estradiol-dependent proliferation of MCF7 cells weakly but estradiol-induced AlkP (alkaline phosphatase) expression only marginally .
|
-
| Cat. No. |
Product Name |
Type |
-
- HY-W354066
-
|
|
Carbohydrates
|
|
Biochanin A-7-O-β-D-glucuronide is a glucuronidated derivative of phytoestrogen, which has the ability to study the metabolic activity of phytoestrogen in the ecosystem. Biochanin A-7-O-β-D-glucuronide plays an important role in ecological research. Biochanin A-7-O-β-D-glucuronide is used to explore the interaction between plants and the environment.
|
| Cat. No. |
Product Name |
Category |
Target |
Chemical Structure |
-
- HY-N0595
-
-
-
- HY-N0235
-
-
-
- HY-N1461
-
-
-
- HY-N0553
-
-
-
- HY-108052
-
|
Delphinidin 3-O-glucoside chloride; Delphinidin 3-O-β-glucoside chloride
|
Malvaceae
Anthocyans
Flavonoids
Microorganisms
Classification of Application Fields
Hibiscus sabdariffa Linn.
Source classification
Plants
Disease Research Fields
Cancer
|
EGFR
Apoptosis
Akt
|
|
Delphinidin 3-glucoside chloride (Delphinidin 3-O-glucoside chloride) is an active anthocyanin found in Hibiscus sabdariffa extract. Delphinidin 3-glucoside chloride induces a pro-apoptotic effect in B cell chronic lymphocytic leukaemia (B CLL) . Delphinidin 3-glucoside chloride exerts phytoestrogen activity by binding to ERβ, with an IC50 of 9.7 μM . Delphinidin-3-O-glucoside chloride inhibits EGFR with an IC50 of 2.37 µM . Delphinidin 3-glucoside chloride exhibits antitumor effects through pAKT/IRF1/HOTAIR pathway. Delphinidin 3-glucoside chloride exhibits efficacy against oxidative stress, inhibits platelet activation and endothelial dysfunction .
|
-
-
- HY-N8366
-
-
-
- HY-N0595R
-
-
-
- HY-N0235R
-
|
(S)-(+)-Bakuchiol (Standard)
|
Monophenols
Leguminosae
Source classification
Phenols
Psoralea corylifolia L.
Plants
|
Carboxylesterase (CES)
Reference Standards
p38 MAPK
Autophagy
UGT
|
|
Bakuchiol (Standard) is the analytical standard of Bakuchiol. This product is intended for research and analytical applications. Bakuchiol is a phytoestrogen that can be obtained from psoralen seeds. Bakuchiol has been proven to be a non-competitive inhibitor of multiple enzymes, including UDP-glucuronosyltransferase 2B7 (UGT2B7) and human carboxylesterase 2 (hCE2) , with IC50s values of 40.9 μM and 7.28 μM, respectively. Bakuchiol exhibits significant research and application potential in areas such as anti-inflammatory , antibacterial , antitumor therapies, as well as drug metabolism regulation.
|
-
-
- HY-N4200
-
-
-
- HY-108052R
-
|
Delphinidin 3-O-glucoside chloride (Standard); Delphinidin 3-O-β-glucoside chloride (Standard)
|
Malvaceae
Anthocyans
Flavonoids
Microorganisms
Hibiscus sabdariffa Linn.
Source classification
Plants
|
Reference Standards
EGFR
Apoptosis
Akt
|
|
Delphinidin 3-glucoside (chloride) (Standard) is the analytical standard of Delphinidin 3-glucoside (chloride). This product is intended for research and analytical applications. Delphinidin 3-glucoside chloride (Delphinidin 3-O-glucoside chloride) is an active anthocyanin found in Hibiscus sabdariffa extract. Delphinidin 3-glucoside chloride induces a pro-apoptotic effect in B cell chronic lymphocytic leukaemia (B CLL) . Delphinidin 3-glucoside chloride exerts phytoestrogen activity by binding to ERβ, with an IC50 of 9.7 μM . Delphinidin-3-O-glucoside chloride inhibits EGFR with an IC50 of 2.37 µM . Delphinidin 3-glucoside chloride exhibits antitumor effects through pAKT/IRF1/HOTAIR pathway. Delphinidin 3-glucoside chloride exhibits efficacy against oxidative stress, inhibits platelet activation and endothelial dysfunction .
|
-
-
- HY-N3755
-
-
-
- HY-N2335
-
-
-
- HY-N6787R
-
-
-
- HY-N0553R
-
-
-
- HY-N0233
-
-
-
- HY-N0791
-
-
-
- HY-N2335R
-
-
-
- HY-N0233R
-
-
-
- HY-W006405
-
-
-
- HY-N0791R
-
-
-
- HY-114367
-
-
-
- HY-W006405R
-
|
|
Flavonoids
Leguminosae
Glycine max (L.) merr
Source classification
Plants
Isoflavones
|
Reference Standards
Others
|
|
Isoflavone (Standard) is the analytical standard of Isoflavone. This product is intended for research and analytical applications. Isoflavone is an orally available bioactive component of soy phytoestrogen with lipid-lowering and antioxidant activities. Isoflavone prevents a variety of chronic diseases by regulating fatty acid oxidation in the liver and gene expression in adipose tissue. In addition, isoflavone has important value in the research of cancer and cardiovascular diseases .
|
-
-
- HY-B2171AR
-
|
Carminomycin hydrochloride (Standard); Carminomicin I hydrochloride (Standard)
|
Quinones
Microorganisms
Anthraquinones
Source classification
Phenols
Polyphenols
|
Reference Standards
Apoptosis
|
|
Isoflavone (Standard) is the analytical standard of Isoflavone. This product is intended for research and analytical applications. Isoflavone is an orally available bioactive component of soy phytoestrogen with lipid-lowering and antioxidant activities. Isoflavone prevents a variety of chronic diseases by regulating fatty acid oxidation in the liver and gene expression in adipose tissue. In addition, isoflavone has important value in the research of cancer and cardiovascular diseases .
|
-
-
- HY-131586
-
|
Resogalangin
|
Flavonoids
Flavones
Source classification
Plants
Fabaceae
Zuccagnia punctata Cav.
|
17β-HSD
Estrogen Receptor/ERR
Aldose Reductase
|
|
3,7-Dihydroxyflavone (Resogalangin) is a flavonoid phytoestrogen, which can be isolated from Adenophora species. 3,7-Dihydroxyflavone is a modulator of estrogen receptors and an inhibitor of human progesterone metabolizing enzyme AKR1C1 and fungal 17β-hydroxysteroid dehydrogenase and a redox inhibitor (IC50=0.6 and 6.0 μM, respectively). 3,7-Dihydroxyflavone is a fluorescent binding substrate for human serum albumin (HSA) with excitation wavelengths of 370 nm (pH 7.4) and 350 nm (pH 3.5), respectively, and emission wavelength of 515 nm .
|
-
-
- HY-113382R
-
|
1-Methylhydantoin (Standard)
|
Alkaloids
Other Alkaloids
Source classification
Endogenous metabolite
|
Reference Standards
Endogenous Metabolite
|
|
Delphinidin 3-glucoside (chloride) (Standard) is the analytical standard of Delphinidin 3-glucoside (chloride). This product is intended for research and analytical applications. Delphinidin 3-glucoside chloride (Delphinidin 3-O-glucoside chloride) is an active anthocyanin found in Hibiscus sabdariffa extract. Delphinidin 3-glucoside chloride induces a pro-apoptotic effect in B cell chronic lymphocytic leukaemia (B CLL) . Delphinidin 3-glucoside chloride exerts phytoestrogen activity by binding to ERβ, with an IC50 of 9.7 μM . Delphinidin-3-O-glucoside chloride inhibits EGFR with an IC50 of 2.37 µM . Delphinidin 3-glucoside chloride exhibits antitumor effects through pAKT/IRF1/HOTAIR pathway. Delphinidin 3-glucoside chloride exhibits efficacy against oxidative stress, inhibits platelet activation and endothelial dysfunction .
|
-
-
- HY-119539
-
-
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