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phosphoenolpyruvate

" in MedChemExpress (MCE) Product Catalog:

By Targets:	PEPCK (1) Biochemical Assay Reagents (1) Endogenous Metabolite (12) GABA Receptor (1) Histone Demethylase (1) Isotope-Labeled Compounds (1) Monoamine Oxidase (1) PKC (1) Pyruvate Kinase (3) Reference Standards (1)
By Research Areas:	Cancer (3) Cardiovascular Disease (3) Inflammation/Immunology (1) Metabolic Disease (16) Neurological Disease (1)

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Isotope-Labeled Compounds

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Targets Recommended: PEPCK

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-E70015

Phosphoenolpyruvate carboxylase, Microorganism PEPC	Others	Others
Phosphoenolpyruvate carboxylase, Microorganism (PEPC) is a carbon dioxide fixing enzyme that in an irreversible manner and in the presence of Mg ²⁺, converts phosphoenolpyruvate and bicarbonate into oxaloacetate and inorganic phosphorus. Phosphoenolpyruvate carboxylase catalyses the primary assimilation of CO(2) in Crassulacean acid metabolism plants. Phosphoenolpyruvate carboxylase plays a major role in setting the day-night pattern of metabolism in plants .

HY-W008807

Phosphoenolpyruvic acid potassium 1 Publications Verification phosphoenolpyruvate potassium	Endogenous Metabolite	Metabolic Disease
Phosphoenolpyruvic acid (Phosphoenolpyruvate) potassium is a glycolysis metabolite with a high-energy phosphate group. Phosphoenolpyruvic acid potassium is involved in glycolysis and gluconeogenesis, and used as energy source to produce ATP, under the energy-limited conditions. Phosphoenolpyruvic acid potassium also exhibits cytoprotective and anti-oxidative properties .

HY-W011704

Phosphoenolpyruvic acid cyclohexylammonium salt 1 Publications Verification phosphoenolpyruvate cyclohexylammonium salt	Endogenous Metabolite	Metabolic Disease
Phosphoenolpyruvic acid (Phosphoenolpyruvate) cyclohexylammonium salt is a glycolysis metabolite with a high-energy phosphate group. Phosphoenolpyruvic acid cyclohexylammonium salt is involved in glycolysis and gluconeogenesis, and used as energy source to produce ATP, under the energy-limited conditions. Phosphoenolpyruvic acid cyclohexylammonium salt also exhibits cytoprotective and anti-oxidative properties .

HY-W011704A

Phosphoenolpyruvic acid tricyclohexylammonium salt 1 Publications Verification phosphoenolpyruvate tricyclohexylammonium salt	Endogenous Metabolite	Metabolic Disease
Phosphoenolpyruvic acid (Phosphoenolpyruvate) tricyclohexylammonium salt is a glycolysis metabolite with a high-energy phosphate group. Phosphoenolpyruvic acid tricyclohexylammonium salt is involved in glycolysis and gluconeogenesis, and used as energy source to produce ATP, under the energy-limited conditions. Phosphoenolpyruvic acid tricyclohexylammonium salt also exhibits cytoprotective and anti-oxidative properties .

HY-W008807S

Phosphoenolpyruvic acid potassium-13C2 phosphoenolpyruvate potassium-¹³C₂	Isotope-Labeled Compounds Endogenous Metabolite	Metabolic Disease
Phosphoenolpyruvic acid (potassium)- ¹³C₂ is the ¹³C labeled Phosphoenolpyruvic acid potassium (HY-W008807) . Phosphoenolpyruvic acid (Phosphoenolpyruvate) potassium is a glycolysis metabolite with a high-energy phosphate group. Phosphoenolpyruvic acid potassium is involved in glycolysis and gluconeogenesis, and used as energy source to produce ATP, under the energy-limited conditions. Phosphoenolpyruvic acid potassium also exhibits cytoprotective and anti-oxidative properties .

HY-W008807R

Phosphoenolpyruvic acid potassium (Standard) phosphoenolpyruvate potassium (Standard)	Reference Standards Endogenous Metabolite	Metabolic Disease
Phosphoenolpyruvic acid potassium (Standard) (Potassium 1-carboxyvinyl hydrogenphosphate (Standard)) is the analytical standard of Phosphoenolpyruvic acid potassium (HY-W008807). This product is intended for research and analytical applications. Phosphoenolpyruvic acid potassium is a glycolysis metabolite with a high-energy phosphate group. Phosphoenolpyruvic acid potassium is involved in glycolysis and gluconeogenesis, and used as energy source to produce ATP, under the energy-limited conditions. Phosphoenolpyruvic acid potassium also exhibits cytoprotective and anti-oxidative properties.

HY-113049

Phosphoenolpyruvic acid phosphoenolpyruvate	Endogenous Metabolite	Metabolic Disease
Phosphoenolpyruvic acid (Phosphoenolpyruvate) is a glycolysis metabolite with a high-energy phosphate group. Phosphoenolpyruvic acid is involved in glycolysis and gluconeogenesis, and used as energy source to produce ATP, under the energy-limited conditions. Phosphoenolpyruvic acid also exhibits cytoprotective and anti-oxidative properties .

HY-CE01731

Phosphoenolpyruvate-CoA phosphoenolpyruvate-coenzyme A	Biochemical Assay Reagents	Metabolic Disease
Phosphoenolpyruvate-CoA (Phosphoenolpyruvate-coenzyme A) is a coenzyme A derivative .

HY-113049A

Phosphoenolpyruvic acid trisodium phosphoenolpyruvate trisodium	Endogenous Metabolite	Metabolic Disease
Phosphoenolpyruvic acid (Phosphoenolpyruvate) trisodium is a glycolysis metabolite with a high-energy phosphate group. Phosphoenolpyruvic acid trisodium is involved in glycolysis and gluconeogenesis, and used as energy source to produce ATP, under the energy-limited conditions. Phosphoenolpyruvic acid trisodium also exhibits cytoprotective and anti-oxidative properties .

HY-W555010

Phosphoenolpyruvic acid monosodium phosphoenolpyruvate monosodium	Endogenous Metabolite	Metabolic Disease
Phosphoenolpyruvic acid (Phosphoenolpyruvate) monosodium is a glycolysis metabolite with a high-energy phosphate group. Phosphoenolpyruvic acid monosodium is involved in glycolysis and gluconeogenesis, and used as energy source to produce ATP, under the energy-limited conditions. Phosphoenolpyruvic acid monosodium also exhibits cytoprotective and anti-oxidative properties .

HY-N13191

Ingenol 3-monobenzoate Ingenol 3-benzoate	PKC	Others
Ingenol 3-monobenzoate (Ingenol 3-benzoate) is a disgust inducing agent. Ingenol 3-monobenzoate can bind to and activate PKC (K_i=0.14 nM), inhibit the gene expression of phosphoenolpyruvate carboxykinase, thereby inhibiting gluconeogenesis, and increasing blood cortisol levels, producing food aversion .

HY-P2806

Pyruvate Kinase, Microorganism PK; Fluorokinase	Endogenous Metabolite	Metabolic Disease Cancer
Pyruvate Kinase, Microorganism (PK) is a glycolytic enzyme that catalyzes the conversion of phosphoenolpyruvate and ADP to pyruvate and ATP .

HY-113167

2-Phosphoglyceric acid DL-2-phosphoglyceric acid	Endogenous Metabolite	Metabolic Disease
2-Phosphoglyceric acid (DL-2-phosphoglyceric acid) is a glycolysis substrate. It is catalyzed by enolase into phosphoenolpyruvate (PEP) .

HY-110124

ML202	Pyruvate Kinase	Cancer
ML202 is a highly specific allosteric activator of human pyruvate kinase M2 (hPK-M2), which can affect the cooperativity of phosphoenolpyruvate (PEP) binding, while adenosine diphosphate (ADP) binding almost no effect .

HY-W011704AR

Phosphoenolpyruvic acid tricyclohexylammonium salt (Standard)	Endogenous Metabolite	Metabolic Disease
Phosphoenolpyruvic acid (Phosphoenolpyruvate) tricyclohexylammonium salt is a glycolysis metabolite with a high-energy phosphate group. Phosphoenolpyruvic acid tricyclohexylammonium salt is involved in glycolysis and gluconeogenesis, and used as energy source to produce ATP, under the energy-limited conditions. Phosphoenolpyruvic acid tricyclohexylammonium salt also exhibits cytoprotective and anti-oxidative properties .

HY-128923

SKF-34288 hydrochloride Maximum Cited Publications 8 Publications Verification 3-Mercaptopicolinic acid hydrochloride; 3-MPA hydrochloride	PEPCK	Metabolic Disease
SKF-34288 (3-Mercaptopicolinic acid) hydrochloride is an orally active phosphoenolpyruvate carboxykinase (PEPCK) inhibitor (K_i: 2-9 μM). SKF-34288 hydrochloride is a potent hypoglycemic agent by inhibiting glucose synthesis. SKF-34288 hydrochloride also inhibits Asn metabolism and increases amino acids and amides .

HY-135883

PKR activator 1	Pyruvate Kinase	Cardiovascular Disease
PKR activator 1 is a potent pyruvate kinase-R (PKR) activator extracted from patent WO2019035865A1, compound E7-93 .

HY-W712327

D-Xylulose 5-phosphate sodium	Others	Others
D-Xylulose 5-phosphate (sodium) is a pentose phosphate ester and an essential intermediate metabolite in the pentose phosphate pathway (PPP) and the non-oxidative phase of the pentose phosphate pathway. D-xylulose-5-phosphate can be efficiently synthesized through the phosphorylation of D-xylulose catalyzed by D-xylulokinase (XKS1 from Saccharomyces cerevisiae), with ATP regeneration facilitated by the phosphoenolpyruvate (PEP)/pyruvate kinase (PK) system .

HY-P2819A

Phosphofructokinase,Bacillus stearothermophilus	Endogenous Metabolite	Metabolic Disease
Phosphofructokinase from Bacillus stearothermophilus is a key enzyme in sugar metabolism that catalyzes the conversion of fructose-6-phosphate to fructose-1,6-bisphosphate during glycolysis. The enzyme's ability to bind fructose-6-phosphate can be inhibited by phosphoenolpyruvate (PEP), thereby regulating the rate of glycolysis. Phosphofructokinase from Bacillus stearothermophilus can be used for the measurement of fructose-6-phosphate levels .

HY-12689C

Mitapivat hydrochloride AG-348 hydrochloride	Pyruvate Kinase	Cardiovascular Disease Metabolic Disease
Mitapivat (AG-348) hydrochloride is an orally active and selective allosteric pyruvate kinase R (PK-R) activator. Mitapivat hydrochloride accelerates the reaction of PK-R catalyzing the conversion of phosphoenolpyruvate to pyruvate, thereby promoting the glycolytic pathway, increasing the production of adenosine triphosphate (ATP) in red blood cells, and reducing the level of 2,3-diphosphoglycerate (2,3-DPG). Mitapivat hydrochloride is promising for research of pyruvate kinase deficiency and other anemia-related diseases .

HY-B1018A

Phenelzine sulfate 5 Publications Verification	Monoamine Oxidase GABA Receptor Histone Demethylase	Cardiovascular Disease Neurological Disease Metabolic Disease Inflammation/Immunology Cancer
Phenelzine sulfate, an antidepressant agent, is an irreversible and orally active monoamine oxidase (MAO-A and MAO-B) inhibitor. Phenelzine sulfate inhibits GABA transaminase and primary amine oxidase (PrAO), and sequester reactive aldehydes. Phenelzine sulfate also inhibits LSD1 (K_i: 5.6 μM) and suppresses oxidative stress and lipogenesis. Phenelzine sulfate elevates neurotransmitters (serotonin, norepinephrine, dopamine). Phenelzine sulfate is studied in neurological, metabolic and cancer diseases for depression and anxiety disorders, stroke, spinal cord injury, traumatic brain injury, multiple sclerosis, Parkinson’s disease, Alzheimer’s disease, inflammatory pain, obesity and prostate cancer .

Cat. No.	Product Name	Type

HY-W011704

Phosphoenolpyruvic acid cyclohexylammonium salt 1 Publications Verification phosphoenolpyruvate cyclohexylammonium salt	Enzyme Substrates
Phosphoenolpyruvic acid (Phosphoenolpyruvate) cyclohexylammonium salt is a glycolysis metabolite with a high-energy phosphate group. Phosphoenolpyruvic acid cyclohexylammonium salt is involved in glycolysis and gluconeogenesis, and used as energy source to produce ATP, under the energy-limited conditions. Phosphoenolpyruvic acid cyclohexylammonium salt also exhibits cytoprotective and anti-oxidative properties .

Phosphoenolpyruvic acid cyclohexylammonium salt

1 Publications Verification

phosphoenolpyruvate cyclohexylammonium salt

Enzyme Substrates

Phosphoenolpyruvic acid (Phosphoenolpyruvate) cyclohexylammonium salt is a glycolysis metabolite with a high-energy phosphate group. Phosphoenolpyruvic acid cyclohexylammonium salt is involved in glycolysis and gluconeogenesis, and used as energy source to produce ATP, under the energy-limited conditions. Phosphoenolpyruvic acid cyclohexylammonium salt also exhibits cytoprotective and anti-oxidative properties .

HY-113049A

Phosphoenolpyruvic acid trisodium phosphoenolpyruvate trisodium	Biochemical Assay Reagents
Phosphoenolpyruvic acid (Phosphoenolpyruvate) trisodium is a glycolysis metabolite with a high-energy phosphate group. Phosphoenolpyruvic acid trisodium is involved in glycolysis and gluconeogenesis, and used as energy source to produce ATP, under the energy-limited conditions. Phosphoenolpyruvic acid trisodium also exhibits cytoprotective and anti-oxidative properties .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-W008807

Phosphoenolpyruvic acid potassium 1 Publications Verification phosphoenolpyruvate potassium	Structural Classification Classification of Application Fields Ketones, Aldehydes, Acids Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	Endogenous Metabolite
Phosphoenolpyruvic acid (Phosphoenolpyruvate) potassium is a glycolysis metabolite with a high-energy phosphate group. Phosphoenolpyruvic acid potassium is involved in glycolysis and gluconeogenesis, and used as energy source to produce ATP, under the energy-limited conditions. Phosphoenolpyruvic acid potassium also exhibits cytoprotective and anti-oxidative properties .

HY-W011704A

Phosphoenolpyruvic acid tricyclohexylammonium salt 1 Publications Verification phosphoenolpyruvate tricyclohexylammonium salt	Structural Classification Classification of Application Fields Ketones, Aldehydes, Acids Source classification Other Diseases Endogenous metabolite Disease Research Fields	Endogenous Metabolite
Phosphoenolpyruvic acid (Phosphoenolpyruvate) tricyclohexylammonium salt is a glycolysis metabolite with a high-energy phosphate group. Phosphoenolpyruvic acid tricyclohexylammonium salt is involved in glycolysis and gluconeogenesis, and used as energy source to produce ATP, under the energy-limited conditions. Phosphoenolpyruvic acid tricyclohexylammonium salt also exhibits cytoprotective and anti-oxidative properties .

HY-W008807R

Phosphoenolpyruvic acid potassium (Standard) phosphoenolpyruvate potassium (Standard)	Structural Classification Ketones, Aldehydes, Acids Source classification Endogenous metabolite	Reference Standards Endogenous Metabolite
Phosphoenolpyruvic acid potassium (Standard) (Potassium 1-carboxyvinyl hydrogenphosphate (Standard)) is the analytical standard of Phosphoenolpyruvic acid potassium (HY-W008807). This product is intended for research and analytical applications. Phosphoenolpyruvic acid potassium is a glycolysis metabolite with a high-energy phosphate group. Phosphoenolpyruvic acid potassium is involved in glycolysis and gluconeogenesis, and used as energy source to produce ATP, under the energy-limited conditions. Phosphoenolpyruvic acid potassium also exhibits cytoprotective and anti-oxidative properties.

HY-N13191

Ingenol 3-monobenzoate Ingenol 3-benzoate	Structural Classification Natural Products Source classification Euphorbia esula L. Euphorbiaceae Plants	PKC
Ingenol 3-monobenzoate (Ingenol 3-benzoate) is a disgust inducing agent. Ingenol 3-monobenzoate can bind to and activate PKC (K_i=0.14 nM), inhibit the gene expression of phosphoenolpyruvate carboxykinase, thereby inhibiting gluconeogenesis, and increasing blood cortisol levels, producing food aversion .

HY-113049

Phosphoenolpyruvic acid phosphoenolpyruvate	Human Gut Microbiota Metabolites Microorganisms Source classification Endogenous metabolite	Endogenous Metabolite
Phosphoenolpyruvic acid (Phosphoenolpyruvate) is a glycolysis metabolite with a high-energy phosphate group. Phosphoenolpyruvic acid is involved in glycolysis and gluconeogenesis, and used as energy source to produce ATP, under the energy-limited conditions. Phosphoenolpyruvic acid also exhibits cytoprotective and anti-oxidative properties .

HY-113167

2-Phosphoglyceric acid DL-2-phosphoglyceric acid	Structural Classification Classification of Application Fields Ketones, Aldehydes, Acids Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	Endogenous Metabolite
2-Phosphoglyceric acid (DL-2-phosphoglyceric acid) is a glycolysis substrate. It is catalyzed by enolase into phosphoenolpyruvate (PEP) .

HY-W011704AR

Phosphoenolpyruvic acid tricyclohexylammonium salt (Standard)	Structural Classification Ketones, Aldehydes, Acids Source classification Endogenous metabolite	Endogenous Metabolite
Phosphoenolpyruvic acid (Phosphoenolpyruvate) tricyclohexylammonium salt is a glycolysis metabolite with a high-energy phosphate group. Phosphoenolpyruvic acid tricyclohexylammonium salt is involved in glycolysis and gluconeogenesis, and used as energy source to produce ATP, under the energy-limited conditions. Phosphoenolpyruvic acid tricyclohexylammonium salt also exhibits cytoprotective and anti-oxidative properties .

Species:	Human (1) E.coli (1)
Tag:	His (2) SUMO (1) GST (1)
Source:	Sf9 insect cells (1) E. coli (1)

Cat. No.	Compare	Product Name	Species	Source

HY-P75957

	PCK2 Protein, Human (sf9, His-GST) phosphoenolpyruvate carboxykinase [GTP], mitochondrial; PEPCK-M; PCK2; PEPCK2	Human	Sf9 insect cells
	As a key enzyme in cellular metabolism, PCK2 protein catalyzes the conversion of oxaloacetate (OAA) into phosphoenolpyruvate (PEP), representing the rate-limiting step in the metabolic pathway and responsible for the production of glucose from other precursors derived from lactate and citric acid. . cycle. PCK2 Protein, Human (sf9, His-GST) is the recombinant human-derived PCK2 protein, expressed by Sf9 insect cells , with C-His, N-GST labeled tag.

HY-P71458

	PpsA Protein, E.coli (His-SUMO) ppsA; pps; b1702; JW1692phosphoenolpyruvate synthase; PEP synthase; EC 2.7.9.2; Pyruvate; water dikinase	E.coli	E. coli
	The PpsA protein plays a crucial role in cellular metabolism by catalyzing the conversion of pyruvate to phosphoenolpyruvate, a key step in glycolysis and gluconeogenesis. This enzyme activity is the basis for the interconversion of metabolic intermediates and contributes to the regulation of intracellular energy production and utilization. PpsA Protein, E.coli (His-SUMO) is the recombinant E. coli-derived PpsA protein, expressed by E. coli , with N-His, N-SUMO labeled tag.

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HY-W008807S

Phosphoenolpyruvic acid potassium-13C2
Phosphoenolpyruvic acid (potassium)- ¹³C₂ is the ¹³C labeled Phosphoenolpyruvic acid potassium (HY-W008807) . Phosphoenolpyruvic acid (Phosphoenolpyruvate) potassium is a glycolysis metabolite with a high-energy phosphate group. Phosphoenolpyruvic acid potassium is involved in glycolysis and gluconeogenesis, and used as energy source to produce ATP, under the energy-limited conditions. Phosphoenolpyruvic acid potassium also exhibits cytoprotective and anti-oxidative properties .

Phosphoenolpyruvic acid potassium-13C2

Phosphoenolpyruvic acid (potassium)- ¹³C₂ is the ¹³C labeled Phosphoenolpyruvic acid potassium (HY-W008807) . Phosphoenolpyruvic acid (Phosphoenolpyruvate) potassium is a glycolysis metabolite with a high-energy phosphate group. Phosphoenolpyruvic acid potassium is involved in glycolysis and gluconeogenesis, and used as energy source to produce ATP, under the energy-limited conditions. Phosphoenolpyruvic acid potassium also exhibits cytoprotective and anti-oxidative properties .

Cat. No.	Compare	Product Name	Application	Reactivity

HY-P81802

	PCK2 Antibody (YA1547) PCK2; PEPCK2; phosphoenolpyruvate carboxykinase [GTP]; mitochondrial; PEPCK-M; phosphoenolpyruvate carboxylase	WB, IHC-F, IHC-P, ICC/IF	Human, Mouse, Rat
	PCK2 Antibody (YA1547) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to PCK2.

HY-P85451

	PCK2 Antibody (YA5143) PCK2; PEPCK2; phosphoenolpyruvate carboxykinase [GTP]; mitochondrial; PEPCK-M; phosphoenolpyruvate carboxylase	WB	Human, Mouse, Rat, Bovine, Dog, Pig
	PCK2 Antibody (YA5143) is a Mouse-derived and non-conjugated monoclonal antibody, targeting to PCK2.