Search Result

Results for "

peptide modification

" in MedChemExpress (MCE) Product Catalog:

By Targets:	ADC Linker (1) Amino Acid Derivatives (1) Biochemical Assay Reagents (50) CaMK (1) Complement System (1) Drug Derivative (2) Drug Metabolite (2) Endothelin Receptor (2) Fluorescent Dye (4) GnRH Receptor (1) Histone Demethylase (1) Histone Methyltransferase (1) JNK (2) Potassium Channel (1)
By Research Areas:	Cancer (5) Cardiovascular Disease (2) Inflammation/Immunology (3) Neurological Disease (2)
Click Chemistry:	Azide (1)

Inhibitors & Agonists

Fluorescent Dye

Biochemical Assay Reagents

Peptides

MCE Kits

Click Chemistry

Targets Recommended: Formyl Peptide Receptor (FPR) Connective Peptide Peptide-Drug Conjugates (PDCs) Natriuretic Peptide Receptor (NPR) RXFP Receptor CGRP Receptor Amyloid-β

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-114350

BDP FL maleimide	Fluorescent Dye	Others
BDP FL maleimide is a thiol-reactive dye (Ex: 503 nm; Em: 509 nm). BDP FL maleimide can be used for protein labeling, peptide modification, and can replace fluorescein (FAM) for microscopy .

HY-P3581

PE 22-28	Potassium Channel	Neurological Disease
PE 22-28 is a TREK-1 inhibitor with IC₅₀ value of 0.12 nM. PE 22-28 also is a 7 amino-acid peptide that is used as a core sequence for preparing analogs by chemical modifications and also by substitution of amino-acids. PE 22-28 can be used for the research of depression .

HY-P5533

CRT	Biochemical Assay Reagents	Cancer
CRT, an iron peptide mimic, can bind to apo-transferrin (apo-Tf). CRT can be used to modify nanoparticles, and enhances drug delivery efficiency .

HY-118093

N-benzoyl-L-aspartic acid	Drug Metabolite	Others
N-benzoyl-L-aspartic acid, a major metabolite of benzyl glucosinolate, can be used for modification of peptides or proteins .

HY-138982

D-2-Thiolhistidine	Biochemical Assay Reagents	Others
D-2-Thiolhistidine can be used for modification of proteins and peptides.

HY-P10499

[Ala286]-Calmodulin-Dependent Protein Kinase II (281-302)	CaMK	Others
[Ala286]-Calmodulin-Dependent Protein Kinase II (281-302) is a modified fragment of calcium/calmodulin-dependent protein kinase II that contains the active domain of CaMKII and has an alanine substitution at position 286. [Ala286]-Calmodulin-Dependent Protein Kinase II (281-302) can be used to develop more potent CaMKII inhibitors .

HY-P10533

Cysteine peptide	Biochemical Assay Reagents	Others
Cysteine peptide is a heptapeptide containing a cysteine residue whose thiol group makes it susceptible to a range of oxidative modifications. Cysteine peptide is used to detect the skin sensitization potential of chemicals including cosmetic ingredients .

HY-W1048512A

2-Arm PEG-NHS (MW 20000)	Biochemical Assay Reagents	Others
2-Arm PEG-NHS (MW 20000) is a multi-arm PEG derivative that can be used for peptide modification and drug delivery .

HY-174959A

6-Arm-PEG-NHS (MW 600)	Biochemical Assay Reagents	Others
6-Arm-PEG-NHS (MW 600) is a six-arm PEG derivative that can be used for peptide modification and drug delivery .

HY-W1048512B

2-Arm PEG-NHS (MW 40000)	Biochemical Assay Reagents	Others
2-Arm PEG-NHS (MW 40000) is a multi-arm PEG derivative that can be used for peptide modification and drug delivery .

HY-174959H

6-Arm-PEG-NHS (MW 10000)	Biochemical Assay Reagents	Others
6-Arm-PEG-NHS (MW 10000) is a six-arm PEG derivative that can be used for peptide modification and drug delivery .

HY-W1048855D

4-Arm PEG-SCM (MW 40000)	Biochemical Assay Reagents	Others
4-Arm PEG-SCM (MW 40000) is a multi-arm PEG derivative that can be used for peptide modification and drug delivery .

HY-174959C

6-Arm-PEG-NHS (MW 2000)	Biochemical Assay Reagents	Others
6-Arm-PEG-NHS (MW 2000) is a six-arm PEG derivative that can be used for peptide modification and drug delivery .

HY-W1048512C

2-Arm PEG-NHS (MW 5000)	Biochemical Assay Reagents	Others
2-Arm PEG-NHS (MW 5000) is a multi-arm PEG derivative that can be used for peptide modification and drug delivery .

HY-W1048855C

4-Arm PEG-SCM (MW 20000)	Biochemical Assay Reagents	Others
4-Arm PEG-SCM (MW 20000) is a multi-arm PEG derivative that can be used for peptide modification and drug delivery .

HY-174959B

6-Arm-PEG-NHS (MW 1000)	Biochemical Assay Reagents	Others
6-Arm-PEG-NHS (MW 1000) is a six-arm PEG derivative that can be used for peptide modification and drug delivery .

HY-W1048855B

4-Arm PEG-SCM (MW 10000)	Biochemical Assay Reagents	Others
4-Arm PEG-SCM (MW 10000) is a multi-arm PEG derivative that can be used for peptide modification and drug delivery .

HY-W1048855A

4-Arm PEG-SCM (MW 5000)	Biochemical Assay Reagents	Others
4-Arm PEG-SCM (MW 5000) is a multi-arm PEG derivative that can be used for peptide modification and drug delivery .

HY-174959

6-Arm-PEG-NHS (MW 400)	Biochemical Assay Reagents	Others
6-Arm-PEG-NHS (MW 400) is a six-arm PEG derivative that can be used for peptide modification and drug delivery .

HY-174959D

6-Arm-PEG-NHS (MW 3400)	Biochemical Assay Reagents	Others
6-Arm-PEG-NHS (MW 3400) is a six-arm PEG derivative that can be used for peptide modification and drug delivery .

HY-W1048512D

2-Arm PEG-NHS (MW 10000)	Biochemical Assay Reagents	Others
2-Arm PEG-NHS (MW 10000) is a multi-arm PEG derivative that can be used for peptide modification and drug delivery .

HY-174959E

6-Arm-PEG-NHS (MW 5000)	Biochemical Assay Reagents	Others
6-Arm-PEG-NHS (MW 5000) is a six-arm PEG derivative that can be used for peptide modification and drug delivery .

HY-W1048851A

4-Arm PEG-MAL (MW 5000)	Biochemical Assay Reagents	Others
4-Arm PEG-MAL (MW 5000) can be used for site-specific protein and peptide modification and can be used for drug delivery .

HY-W1048851D

4-Arm PEG-MAL (MW 40000)	Biochemical Assay Reagents	Others
4-Arm PEG-MAL (MW 40000) can be used for site-specific protein and peptide modification and can be used for drug delivery .

HY-W1048851B

4-Arm PEG-MAL (MW 10000)	Biochemical Assay Reagents	Others
4-Arm PEG-MAL (MW 10000) can be used for site-specific protein and peptide modification and can be used for drug delivery .

HY-W1048851C

4-Arm PEG-MAL (MW 20000)	Biochemical Assay Reagents	Others
4-Arm PEG-MAL (MW 205000) can be used for site-specific protein and peptide modification and can be used for drug delivery .

HY-174358A

HOOC-PEG-COOH (MW 2000)	Biochemical Assay Reagents	Others
HOOC-PEG-COOH (MW 2000) has two active carboxyl groups at both ends, which can selectively react with the amino groups in peptide coupling agents. HOOC-PEG-COOH (MW 2000) is a good cross-linking agent for PEGylation of proteins and peptides, nanoparticles and surface modification .

HY-174358B

HOOC-PEG-COOH (MW 3400)	Biochemical Assay Reagents	Others
HOOC-PEG-COOH (MW 3400) has two active carboxyl groups at both ends, which can selectively react with the amino groups in peptide coupling agents. HOOC-PEG-COOH (MW 3400) is a good cross-linking agent for PEGylation of proteins and peptides, nanoparticles and surface modification .

HY-174358C

HOOC-PEG-COOH (MW 5000)	Biochemical Assay Reagents	Others
HOOC-PEG-COOH (MW 5000) has two active carboxyl groups at both ends, which can selectively react with the amino groups in peptide coupling agents. HOOC-PEG-COOH (MW 5000) is a good cross-linking agent for PEGylation of proteins and peptides, nanoparticles and surface modification .

HY-174358

HOOC-PEG-COOH (MW 1000)	Biochemical Assay Reagents	Others
HOOC-PEG-COOH (MW 1000) has two active carboxyl groups at both ends, which can selectively react with the amino groups in peptide coupling agents. HOOC-PEG-COOH (MW 1000) is a good cross-linking agent for PEGylation of proteins and peptides, nanoparticles and surface modification .

HY-174358D

HOOC-PEG-COOH (MW 10000)	Biochemical Assay Reagents	Others
HOOC-PEG-COOH (MW 10000) has two active carboxyl groups at both ends, which can selectively react with the amino groups in peptide coupling agents. HOOC-PEG-COOH (MW 10000) is a good cross-linking agent for PEGylation of proteins and peptides, nanoparticles and surface modification .

HY-174358E

HOOC-PEG-COOH (MW 20000)	Biochemical Assay Reagents	Others
HOOC-PEG-COOH (MW 20000) has two active carboxyl groups at both ends, which can selectively react with the amino groups in peptide coupling agents. HOOC-PEG-COOH (MW 20000) is a good cross-linking agent for PEGylation of proteins and peptides, nanoparticles and surface modification .

HY-174358H

HOOC-PEG-COOH (MW 40000)	Biochemical Assay Reagents	Others
HOOC-PEG-COOH (MW 40000) has two active carboxyl groups at both ends, which can selectively react with the amino groups in peptide coupling agents. HOOC-PEG-COOH (MW 40000) is a good cross-linking agent for PEGylation of proteins and peptides, nanoparticles and surface modification .

HY-W1048511

2-Arm PEG-NH2 (MW 5000) 2-Arm PEG-Amine (MW 5000)	Biochemical Assay Reagents	Others
2-Arm PEG-NH2 (MW 5000) (2-Arm PEG-Amine (MW 5000)) is a multi-arm PEG derivative that can be used for peptide modification and drug delivery .

HY-W1048511A

2-Arm PEG-NH2 (MW 20000) 2-Arm PEG-Amine (MW 20000)	Biochemical Assay Reagents	Others
2-Arm PEG-NH2 (MW 20000) (2-Arm PEG-Amine (MW 20000)) is a multi-arm PEG derivative that can be used for peptide modification and drug delivery .

HY-W1048511C

2-Arm PEG-NH2 (MW 10000) 2-Arm PEG-Amine (MW 10000)	Biochemical Assay Reagents	Others
2-Arm PEG-NH2 (MW 10000) (2-Arm PEG-Amine (MW 10000)) is a multi-arm PEG derivative that can be used for peptide modification and drug delivery .

HY-118093R

N-benzoyl-L-aspartic acid (Standard)	Drug Metabolite	Others
N-benzoyl-L-aspartic acid (Standard) is the analytical standard of N-benzoyl-L-aspartic acid. This product is intended for research and analytical applications. N-benzoyl-L-aspartic acid, a major metabolite of benzyl glucosinolate, can be used for modification of peptides or proteins .

HY-W1048511B

2-Arm PEG-NH2 (MW 40000) 2-Arm PEG-Amine (MW 40000)	Biochemical Assay Reagents	Others
2-Arm PEG-NH2 (MW 40000) (2-Arm PEG-Amine (MW 40000)) is a multi-arm PEG derivative that can be used for peptide modification and drug delivery .

HY-P1191

JIP-1(153-163) TI-JIP; JIP-1 peptide; JIPtide	JNK	Others
JIP-1(153-163) (TI-JIP) is a peptide inhibitor of c-JNK, based on residues 153-163 of JNK-interacting protein-1 (JIP-1) (Modifications: Phe-11 = C-terminal amide) .

HY-P2255

H3K4(Me) (1-20)	Histone Demethylase	Others
H3K4(Me) (1-20), a histone peptide. H3K4me is an intricately regulated posttranslational modification, which is broadly associated with enhancers and promoters of actively transcribed genomic loci .

HY-P1242B

NEP(1-40), N-terminal uncapped	Drug Derivative	Inflammation/Immunology
NEP(1-40), N-terminal uncapped is a NEP(1-40) (HY-P1242) analog without the acetylation modification at the N-terminal. NEP(1-40) is a Nogo-66 receptor (NgR) antagonist peptide .

HY-174809A

6-Arm-PEG-Mal (MW 600)	Biochemical Assay Reagents	Others
6-Arm-PEG-Mal (MW 600) is a PEG derivative modified with Maleimide (HY-W007324), which forms a stable thioether bond with sulfhydryl (-SH). PEG modification can improve solubility and stability and reduce the immunogenicity of proteins and peptides .

HY-174809E

6-Arm-PEG-Mal (MW 5000)	Biochemical Assay Reagents	Others
6-Arm-PEG-Mal (MW 5000) is a PEG derivative modified with Maleimide (HY-W007324), which forms a stable thioether bond with sulfhydryl (-SH). PEG modification can improve solubility and stability and reduce the immunogenicity of proteins and peptides .

HY-174809H

6-Arm-PEG-Mal (MW 10000)	Biochemical Assay Reagents	Others
6-Arm-PEG-Mal (MW 10000) is a PEG derivative modified with Maleimide (HY-W007324), which forms a stable thioether bond with sulfhydryl (-SH). PEG modification can improve solubility and stability and reduce the immunogenicity of proteins and peptides .

HY-174809

6-Arm-PEG-Mal (MW 400)	Biochemical Assay Reagents	Others
6-Arm-PEG-Mal (MW 400) is a PEG derivative modified with Maleimide (HY-W007324), which forms a stable thioether bond with sulfhydryl (-SH). PEG modification can improve solubility and stability and reduce the immunogenicity of proteins and peptides .

HY-174809C

6-Arm-PEG-Mal (MW 2000)	Biochemical Assay Reagents	Others
6-Arm-PEG-Mal (MW 2000) is a PEG derivative modified with Maleimide (HY-W007324), which forms a stable thioether bond with sulfhydryl (-SH). PEG modification can improve solubility and stability and reduce the immunogenicity of proteins and peptides .

HY-174809D

6-Arm-PEG-Mal (MW 3400)	Biochemical Assay Reagents	Others
6-Arm-PEG-Mal (MW 3400) is a PEG derivative modified with Maleimide (HY-W007324), which forms a stable thioether bond with sulfhydryl (-SH). PEG modification can improve solubility and stability and reduce the immunogenicity of proteins and peptides .

HY-P1191A

JIP-1(153-163) TFA TI-JIP TFA; JIP-1 peptide TFA; JIPtide TFA	JNK	Others
JIP-1(153-163) TFA (TI-JIP TFA) is a peptide inhibitor of c-JNK, based on residues 153-163 of JNK-interacting protein-1 (JIP-1) (Modifications: Phe-11 = C-terminal amide) .

HY-174809B

6-Arm-PEG-Mal (MW 1000)	Biochemical Assay Reagents	Others
6-Arm-PEG-Mal (MW 1000) is a PEG derivative modified with Maleimide (HY-W007324), which forms a stable thioether bond with sulfhydryl (-SH). PEG modification can improve solubility and stability and reduce the immunogenicity of proteins and peptides .

HY-107783

Sulfo-GMBS	Others	Cancer
Sulfo-GMBS is a cross-linking agent widely used in chemical modification and coupling reactions of proteins and peptides. Among the amine-sulfhydryl cross-linkers, Sulfo-GMBS generated the largest number of cross-links and covered most of the cross-links that were identified with AMAS and GMBS .

Cat. No.	Product Name	Type

HY-114350

BDP FL maleimide	Fluorescent Dyes/Probes
BDP FL maleimide is a thiol-reactive dye (Ex: 503 nm; Em: 509 nm). BDP FL maleimide can be used for protein labeling, peptide modification, and can replace fluorescein (FAM) for microscopy .

HY-D1568

Sulfo-Cy7.5 NHS ester	Dyes
Sulfo-Cy7.5 NHS ester is a near infrared water soluble hydrophilic dye, also is an NHS ester for the modification of amine groups. Sulfo-Cy7.5 NHS ester contains a trimeth ylene bridge and has a linker arm for its attachment to proteins, peptides, and other molecules. Sulfo-Cy7.5 NHS ester can be used for the research of NIR imaging applications .

HY-D1568A

Sulfo-Cy7.5 NHS ester tripotassium	Dyes
Sulfo-Cy7.5 NHS ester tripotassium is a near infrared water soluble hydrophilic dye, also is an NHS ester for the modification of amine groups. Sulfo-Cy7.5 NHS ester tripotassium contains a trimeth ylene bridge and has a linker arm for its attachment to proteins, peptides, and other molecules. Sulfo-Cy7.5 NHS ester tripotassium can be used for the research of NIR imaging applications .

HY-D2747

BP Fluor 405 acid

Fluorescent Dyes/Probes

BP Fluor 405 acid is a water-soluble, blue-fluorescent dye that is often used in multi-color applications, including flow cytometry and super-resolution microscopy using STORM. Its excitation is ideally suited for the 407 nm spectral line of the krypton laser or the 408 nm violet laser diode. BP Fluor 405 conjugates are pH-insensitive from pH 4 to pH 10. The carboxylic acid of BP Fluor 405 is a reagent of choice for the preparation of custom activated esters that often are not commercially available. Examples of such activated esters include sulfo-NHS, TFP (2,3,5,6-Tetrafluorophenol), and STP (4-Sulfo-2,3,5,6-Tetrafluorophenol, Sodium Salt). Another common application for the non-activated carboxylic acid is peptide modification during solid phase synthesis, which usually requires in-situ activation with peptide coupling regents, e.g. HATU. BP Fluor 405 acid is also often used for control experiments, and for calibration.

Cat. No.	Product Name	Type

HY-W1048855C

4-Arm PEG-SCM (MW 20000)	Drug Delivery
4-Arm PEG-SCM (MW 20000) is a multi-arm PEG derivative that can be used for peptide modification and drug delivery .

HY-W1048855B

4-Arm PEG-SCM (MW 10000)	Drug Delivery
4-Arm PEG-SCM (MW 10000) is a multi-arm PEG derivative that can be used for peptide modification and drug delivery .

HY-W1048512A

2-Arm PEG-NHS (MW 20000)	Drug Delivery
2-Arm PEG-NHS (MW 20000) is a multi-arm PEG derivative that can be used for peptide modification and drug delivery .

HY-174959A

6-Arm-PEG-NHS (MW 600)	Drug Delivery
6-Arm-PEG-NHS (MW 600) is a six-arm PEG derivative that can be used for peptide modification and drug delivery .

HY-W1048512B

2-Arm PEG-NHS (MW 40000)	Drug Delivery
2-Arm PEG-NHS (MW 40000) is a multi-arm PEG derivative that can be used for peptide modification and drug delivery .

HY-174959H

6-Arm-PEG-NHS (MW 10000)	Drug Delivery
6-Arm-PEG-NHS (MW 10000) is a six-arm PEG derivative that can be used for peptide modification and drug delivery .

HY-W1048855D

4-Arm PEG-SCM (MW 40000)	Drug Delivery
4-Arm PEG-SCM (MW 40000) is a multi-arm PEG derivative that can be used for peptide modification and drug delivery .

HY-174959C

6-Arm-PEG-NHS (MW 2000)	Drug Delivery
6-Arm-PEG-NHS (MW 2000) is a six-arm PEG derivative that can be used for peptide modification and drug delivery .

HY-W1048512C

2-Arm PEG-NHS (MW 5000)	Drug Delivery
2-Arm PEG-NHS (MW 5000) is a multi-arm PEG derivative that can be used for peptide modification and drug delivery .

HY-174959B

6-Arm-PEG-NHS (MW 1000)	Drug Delivery
6-Arm-PEG-NHS (MW 1000) is a six-arm PEG derivative that can be used for peptide modification and drug delivery .

HY-W1048855A

4-Arm PEG-SCM (MW 5000)	Drug Delivery
4-Arm PEG-SCM (MW 5000) is a multi-arm PEG derivative that can be used for peptide modification and drug delivery .

HY-174959

6-Arm-PEG-NHS (MW 400)	Drug Delivery
6-Arm-PEG-NHS (MW 400) is a six-arm PEG derivative that can be used for peptide modification and drug delivery .

HY-174959D

6-Arm-PEG-NHS (MW 3400)	Drug Delivery
6-Arm-PEG-NHS (MW 3400) is a six-arm PEG derivative that can be used for peptide modification and drug delivery .

HY-W1048512D

2-Arm PEG-NHS (MW 10000)	Drug Delivery
2-Arm PEG-NHS (MW 10000) is a multi-arm PEG derivative that can be used for peptide modification and drug delivery .

HY-174959E

6-Arm-PEG-NHS (MW 5000)	Drug Delivery
6-Arm-PEG-NHS (MW 5000) is a six-arm PEG derivative that can be used for peptide modification and drug delivery .

HY-W1048851A

4-Arm PEG-MAL (MW 5000)	Drug Delivery
4-Arm PEG-MAL (MW 5000) can be used for site-specific protein and peptide modification and can be used for drug delivery .

HY-W1048851D

4-Arm PEG-MAL (MW 40000)	Drug Delivery
4-Arm PEG-MAL (MW 40000) can be used for site-specific protein and peptide modification and can be used for drug delivery .

HY-W1048851B

4-Arm PEG-MAL (MW 10000)	Drug Delivery
4-Arm PEG-MAL (MW 10000) can be used for site-specific protein and peptide modification and can be used for drug delivery .

HY-W1048851C

4-Arm PEG-MAL (MW 20000)	Drug Delivery
4-Arm PEG-MAL (MW 205000) can be used for site-specific protein and peptide modification and can be used for drug delivery .

HY-174358A

HOOC-PEG-COOH (MW 2000)	Drug Delivery
HOOC-PEG-COOH (MW 2000) has two active carboxyl groups at both ends, which can selectively react with the amino groups in peptide coupling agents. HOOC-PEG-COOH (MW 2000) is a good cross-linking agent for PEGylation of proteins and peptides, nanoparticles and surface modification .

HY-174358B

HOOC-PEG-COOH (MW 3400)	Drug Delivery
HOOC-PEG-COOH (MW 3400) has two active carboxyl groups at both ends, which can selectively react with the amino groups in peptide coupling agents. HOOC-PEG-COOH (MW 3400) is a good cross-linking agent for PEGylation of proteins and peptides, nanoparticles and surface modification .

HY-174358C

HOOC-PEG-COOH (MW 5000)	Drug Delivery
HOOC-PEG-COOH (MW 5000) has two active carboxyl groups at both ends, which can selectively react with the amino groups in peptide coupling agents. HOOC-PEG-COOH (MW 5000) is a good cross-linking agent for PEGylation of proteins and peptides, nanoparticles and surface modification .

HY-174358

HOOC-PEG-COOH (MW 1000)	Drug Delivery
HOOC-PEG-COOH (MW 1000) has two active carboxyl groups at both ends, which can selectively react with the amino groups in peptide coupling agents. HOOC-PEG-COOH (MW 1000) is a good cross-linking agent for PEGylation of proteins and peptides, nanoparticles and surface modification .

HY-174358D

HOOC-PEG-COOH (MW 10000)	Drug Delivery
HOOC-PEG-COOH (MW 10000) has two active carboxyl groups at both ends, which can selectively react with the amino groups in peptide coupling agents. HOOC-PEG-COOH (MW 10000) is a good cross-linking agent for PEGylation of proteins and peptides, nanoparticles and surface modification .

HY-174358E

HOOC-PEG-COOH (MW 20000)	Drug Delivery
HOOC-PEG-COOH (MW 20000) has two active carboxyl groups at both ends, which can selectively react with the amino groups in peptide coupling agents. HOOC-PEG-COOH (MW 20000) is a good cross-linking agent for PEGylation of proteins and peptides, nanoparticles and surface modification .

HY-174358H

HOOC-PEG-COOH (MW 40000)	Drug Delivery
HOOC-PEG-COOH (MW 40000) has two active carboxyl groups at both ends, which can selectively react with the amino groups in peptide coupling agents. HOOC-PEG-COOH (MW 40000) is a good cross-linking agent for PEGylation of proteins and peptides, nanoparticles and surface modification .

HY-W1048511

2-Arm PEG-NH2 (MW 5000) 2-Arm PEG-Amine (MW 5000)	Drug Delivery
2-Arm PEG-NH2 (MW 5000) (2-Arm PEG-Amine (MW 5000)) is a multi-arm PEG derivative that can be used for peptide modification and drug delivery .

HY-W1048511A

2-Arm PEG-NH2 (MW 20000) 2-Arm PEG-Amine (MW 20000)	Drug Delivery
2-Arm PEG-NH2 (MW 20000) (2-Arm PEG-Amine (MW 20000)) is a multi-arm PEG derivative that can be used for peptide modification and drug delivery .

HY-W1048511C

2-Arm PEG-NH2 (MW 10000) 2-Arm PEG-Amine (MW 10000)	Drug Delivery
2-Arm PEG-NH2 (MW 10000) (2-Arm PEG-Amine (MW 10000)) is a multi-arm PEG derivative that can be used for peptide modification and drug delivery .

HY-W1048511B

2-Arm PEG-NH2 (MW 40000) 2-Arm PEG-Amine (MW 40000)	Drug Delivery
2-Arm PEG-NH2 (MW 40000) (2-Arm PEG-Amine (MW 40000)) is a multi-arm PEG derivative that can be used for peptide modification and drug delivery .

HY-174809A

6-Arm-PEG-Mal (MW 600)	Drug Delivery
6-Arm-PEG-Mal (MW 600) is a PEG derivative modified with Maleimide (HY-W007324), which forms a stable thioether bond with sulfhydryl (-SH). PEG modification can improve solubility and stability and reduce the immunogenicity of proteins and peptides .

HY-174809E

6-Arm-PEG-Mal (MW 5000)	Drug Delivery
6-Arm-PEG-Mal (MW 5000) is a PEG derivative modified with Maleimide (HY-W007324), which forms a stable thioether bond with sulfhydryl (-SH). PEG modification can improve solubility and stability and reduce the immunogenicity of proteins and peptides .

HY-174809H

6-Arm-PEG-Mal (MW 10000)	Drug Delivery
6-Arm-PEG-Mal (MW 10000) is a PEG derivative modified with Maleimide (HY-W007324), which forms a stable thioether bond with sulfhydryl (-SH). PEG modification can improve solubility and stability and reduce the immunogenicity of proteins and peptides .

HY-174809

6-Arm-PEG-Mal (MW 400)	Drug Delivery
6-Arm-PEG-Mal (MW 400) is a PEG derivative modified with Maleimide (HY-W007324), which forms a stable thioether bond with sulfhydryl (-SH). PEG modification can improve solubility and stability and reduce the immunogenicity of proteins and peptides .

HY-174809C

6-Arm-PEG-Mal (MW 2000)	Drug Delivery
6-Arm-PEG-Mal (MW 2000) is a PEG derivative modified with Maleimide (HY-W007324), which forms a stable thioether bond with sulfhydryl (-SH). PEG modification can improve solubility and stability and reduce the immunogenicity of proteins and peptides .

HY-174809D

6-Arm-PEG-Mal (MW 3400)	Drug Delivery
6-Arm-PEG-Mal (MW 3400) is a PEG derivative modified with Maleimide (HY-W007324), which forms a stable thioether bond with sulfhydryl (-SH). PEG modification can improve solubility and stability and reduce the immunogenicity of proteins and peptides .

HY-174809B

6-Arm-PEG-Mal (MW 1000)	Drug Delivery
6-Arm-PEG-Mal (MW 1000) is a PEG derivative modified with Maleimide (HY-W007324), which forms a stable thioether bond with sulfhydryl (-SH). PEG modification can improve solubility and stability and reduce the immunogenicity of proteins and peptides .

HY-W591618A

4-Arm-PEG-Maleimide (MW 400) 4-Arm-PEG-Mal (MW 400)	Drug Delivery
4-Arm-PEG-Maleimide (MW 400) (4-Arm-PEG-Mal (MW 400)) is a PEG derivative modified with Maleimide (HY-W007324), which forms a stable thioether bond with sulfhydryl (-SH). PEG modification can improve solubility and stability and reduce the immunogenicity of proteins and peptides .

HY-W591618D

4-Arm-PEG-Maleimide (MW 3400) 4-Arm-PEG-Mal (MW 3400)	Drug Delivery
4-Arm-PEG-Maleimide (MW 3400) (4-Arm-PEG-Mal (MW 3400)) is a PEG derivative modified with Maleimide (HY-W007324), which forms a stable thioether bond with sulfhydryl (-SH). PEG modification can improve solubility and stability and reduce the immunogenicity of proteins and peptides .

HY-W591618B

4-Arm-PEG-Maleimide (MW 600) 4-Arm-PEG-Mal (MW 600)	Drug Delivery
4-Arm-PEG-Maleimide (MW 600) (4-Arm-PEG-Mal (MW 600)) is a PEG derivative modified with Maleimide (HY-W007324), which forms a stable thioether bond with sulfhydryl (-SH). PEG modification can improve solubility and stability and reduce the immunogenicity of proteins and peptides .

HY-W591465

4-Arm-PEG-Maleimide (MW 2000) 4-Arm-PEG-Mal (MW 2000)	Drug Delivery
4-Arm-PEG-Maleimide (MW 2000) (4-Arm-PEG-Mal (MW 2000)) is a PEG derivative modified with Maleimide (HY-W007324), which forms a stable thioether bond with sulfhydryl (-SH). PEG modification can improve solubility and stability and reduce the immunogenicity of proteins and peptides .

HY-W591618C

4-Arm-PEG-Maleimide (MW 1000) 4-Arm-PEG-Mal (MW 1000)	Drug Delivery
4-Arm-PEG-Maleimide (MW 1000) (4-Arm-PEG-Mal (MW 1000)) is a PEG derivative modified with Maleimide (HY-W007324), which forms a stable thioether bond with sulfhydryl (-SH). PEG modification can improve solubility and stability and reduce the immunogenicity of proteins and peptides .

HY-174961C

Fmoc-PEG-Maleimide (MW 5000)

Fmoc-NH-PEG-Mal (MW 5000)

Drug Delivery

Fmoc-PEG-Maleimide (MW 5000) (Fmoc-NH-PEG-Mal (MW 5000)) is a PEG derivative with an Fmoc protecting group and a Maleimide (HY-W007324) reactive group. Fmoc is a commonly used amino protecting group that protects the amino group from unwanted reactions until it is removed for a specific coupling reaction. Maleimide forms a stable thioether bond with sulfhydryl (-SH) groups. PEG modification can improve solubility and stability and reduce the immunogenicity of proteins and peptides .

HY-174961B

Fmoc-PEG-Maleimide (MW 3400)

Fmoc-NH-PEG-Mal (MW 3400)

Drug Delivery

Fmoc-PEG-Maleimide (MW 3400) (Fmoc-NH-PEG-Mal (MW 3400)) is a PEG derivative with an Fmoc protecting group and a Maleimide (HY-W007324) reactive group. Fmoc is a commonly used amino protecting group that protects the amino group from unwanted reactions until it is removed for a specific coupling reaction. Maleimide forms a stable thioether bond with sulfhydryl (-SH) groups. PEG modification can improve solubility and stability and reduce the immunogenicity of proteins and peptides .

HY-174961

Fmoc-PEG-Maleimide (MW 1000)

Fmoc-NH-PEG-Mal (MW 1000)

Drug Delivery

Fmoc-PEG-Maleimide (MW 1000) (Fmoc-NH-PEG-Mal (MW 1000)) is a PEG derivative with an Fmoc protecting group and a Maleimide (HY-W007324) reactive group. Fmoc is a commonly used amino protecting group that protects the amino group from unwanted reactions until it is removed for a specific coupling reaction. Maleimide forms a stable thioether bond with sulfhydryl (-SH) groups. PEG modification can improve solubility and stability and reduce the immunogenicity of proteins and peptides .

HY-174961A

Fmoc-PEG-Maleimide (MW 2000)

Fmoc-NH-PEG-Mal (MW 2000)

Drug Delivery

Fmoc-PEG-Maleimide (MW 2000) (Fmoc-NH-PEG-Mal (MW 2000)) is a PEG derivative with an Fmoc protecting group and a Maleimide (HY-W007324) reactive group. Fmoc is a commonly used amino protecting group that protects the amino group from unwanted reactions until it is removed for a specific coupling reaction. Maleimide forms a stable thioether bond with sulfhydryl (-SH) groups. PEG modification can improve solubility and stability and reduce the immunogenicity of proteins and peptides .

Cat. No.	Product Name	Target	Research Area

HY-P3581

PE 22-28	Potassium Channel	Neurological Disease
PE 22-28 is a TREK-1 inhibitor with IC₅₀ value of 0.12 nM. PE 22-28 also is a 7 amino-acid peptide that is used as a core sequence for preparing analogs by chemical modifications and also by substitution of amino-acids. PE 22-28 can be used for the research of depression .

HY-P5533

CRT	Biochemical Assay Reagents	Cancer
CRT, an iron peptide mimic, can bind to apo-transferrin (apo-Tf). CRT can be used to modify nanoparticles, and enhances drug delivery efficiency .

HY-P1191

JIP-1(153-163) TI-JIP; JIP-1 peptide; JIPtide	JNK	Others
JIP-1(153-163) (TI-JIP) is a peptide inhibitor of c-JNK, based on residues 153-163 of JNK-interacting protein-1 (JIP-1) (Modifications: Phe-11 = C-terminal amide) .

HY-P2255

H3K4(Me) (1-20)	Histone Demethylase	Others
H3K4(Me) (1-20), a histone peptide. H3K4me is an intricately regulated posttranslational modification, which is broadly associated with enhancers and promoters of actively transcribed genomic loci .

HY-P1242B

NEP(1-40), N-terminal uncapped	Drug Derivative	Inflammation/Immunology
NEP(1-40), N-terminal uncapped is a NEP(1-40) (HY-P1242) analog without the acetylation modification at the N-terminal. NEP(1-40) is a Nogo-66 receptor (NgR) antagonist peptide .

HY-P10499

[Ala286]-Calmodulin-Dependent Protein Kinase II (281-302)	CaMK	Others
[Ala286]-Calmodulin-Dependent Protein Kinase II (281-302) is a modified fragment of calcium/calmodulin-dependent protein kinase II that contains the active domain of CaMKII and has an alanine substitution at position 286. [Ala286]-Calmodulin-Dependent Protein Kinase II (281-302) can be used to develop more potent CaMKII inhibitors .

HY-P4794

Osteoblast-Adhesive Peptide	Peptides	Others
Osteoblast-Adhesive Peptide is a polypeptide used for chemical modification of biomaterials. Osteoclast Adaptive Peptide increases the adhesion of osteoblasts and has potential applications in dentistry and orthopedics .

HY-P10533

Cysteine peptide	Biochemical Assay Reagents	Others
Cysteine peptide is a heptapeptide containing a cysteine residue whose thiol group makes it susceptible to a range of oxidative modifications. Cysteine peptide is used to detect the skin sensitization potential of chemicals including cosmetic ingredients .

HY-P5514

NF(N-Me)GA(N-Me)IL Amylin (22-27) [NMeG24, NMeI26], human (IAPP)	Peptides	Others
NF(N-Me)GA(N-Me)IL is a biological active peptide. (This amino acids 22 to 27 fragment is a modification of the human islet amyloid polypeptide hIAPP (NFGAIL) with N-methylation of the amide bonds at G24 and I26. The introduction of two N-methyl rests in the amyloid-core-containing sequence NFGAIL converts this amyloidogenic and cytotoxic sequence into non-amyloidogenic and non-cytotoxic peptide. The peptide is able to bind with high-affinity full-length hIAPP and to inhibit its fibrillogenesis.)

HY-P1191A

JIP-1(153-163) TFA TI-JIP TFA; JIP-1 peptide TFA; JIPtide TFA	JNK	Others
JIP-1(153-163) TFA (TI-JIP TFA) is a peptide inhibitor of c-JNK, based on residues 153-163 of JNK-interacting protein-1 (JIP-1) (Modifications: Phe-11 = C-terminal amide) .

HY-P2258

Histone H3 (1-34)	Histone Methyltransferase	Others
Histone H3 (1-34) is a peptide derived from human histone isotype 3.1. Histones are the main protein components of eukaryotic chromatin. Histone variants and histone modifications modulate chromatin structure, ensuring the precise operation of cellular processes associated with genomic DNA .

HY-P5506

C5a Receptor agonist, W5Cha	Complement System	Others
C5a Receptor agonist, W5Cha (Peptide 1) is a selective complement C5a receptor (C5aR) agonist (EC₅₀=0.2 μM), a hexapeptide derived from the C-terminus of C5a with specific amino acid modifications. C5a Receptor agonist, W5Cha is able to interact with the Arg-206 site of the C5a receptor through its C-terminal arginine, thereby activating the receptor .

HY-P10490

(D-His(Bzl)6)-LHRH (1-7) free acid	Drug Derivative GnRH Receptor	Others Cancer
(D-His(Bzl)6)-LHRH (1-7) free acid is a synthetic peptide compound that is a derivative of luteinizing hormone-releasing hormone (LHRH). (D-His(Bzl)6)-LHRH (1-7) free acid enhances its stability and biological activity by introducing unnatural amino acid residues at specific positions of the LHRH molecule. This modification can improve the drug's performance in the body half-life, reducing the rate at which it is rapidly metabolized and cleared, thereby enhancing its efficacy in inhibiting cell proliferation .

HY-P10525

MBP Ac1-9 (4Y)	Peptides	Neurological Disease
MBP Ac1-9 (4Y) is a synthetic peptide derived from a fragment of myelin basic protein (MBP) that has undergone specific chemical modifications. MBP Ac1-9 (4Y) is able to form a complex with the MHC class II molecule I-Au and activate specific T cell receptor (TCR), thus playing a role in the pathogenesis of experimental autoimmune encephalomyelitis (EAE). MBP Ac1-9 (4Y) can be used to study autoimmune diseases, especially those involving the central nervous system, such as multiple sclerosis .

Cat. No.	Product Name		Classification

HY-151829

Fmoc-L-Asn(EDA-N3)-OH		Azide
Fmoc-L-Asn(EDA-N3)-OH is a click chemistry reagent containing an azide group. This building block is reported in literature for the modification of Amanitin via Click Chemistry. Alpha-Amanitin is the deadliest member of the amatoxin peptide family produced by the death-cap mushroom A. phalloides. It is an orally available, rigid, bicyclic octapeptide and one of the most lethal known natural products (LD50 = 50-100 μg/kg) acting as highly selective allosteric inhibitor of the RNA polymerase II . It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.

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