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paralysis/death

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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-175339
    Insecticidal agent 25

    		nAChR Infection
    Insecticidal agent 25 (Compound WZ18) is an insecticide targeting the nicotinic acetylcholine receptors (nAChRs) in insect nervous systems. Insecticidal agent 25 disrupts neurotransmission by competitively binding to nAChRs, leading to insect paralysis and death .
    Insecticidal agent 25
  • HY-Z8942
    Avermectin B2a

    		Insecticide Parasite Chloride Channel Infection
    Avermectin B2a is an insecticide targeting glutamate-gated chloride channels (GluCls). Avermectin B2a causes hyperpolarization of nematode/insect neurons and subsequent paralysis/death. Avermectin B2a is promising for research of agricultural pests .
    Avermectin B2a
  • HY-15308B
    Δ2-Avermectin B1a

    		Parasite Chloride Channel Neurological Disease
    Δ²-Avermectin B₁ₐ (Compound 3) is an antiparasitic agent targeting glutamate-gated chloride channels (GluCls) in the neuromuscular system of invertebrates. Δ²-Avermectin B₁ₐ enhances chloride ion influx, leading to hyperpolarization of the neuromuscular cell membrane, inhibition of neural signal transmission, and ultimately paralysis and death of parasites. Δ²-Avermectin B₁ₐ is promising for research of agricultural pests .
    Δ2-Avermectin B1a

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