Search Result
Results for "
pNA
" in MedChemExpress (MCE) Product Catalog:
12
Biochemical Assay Reagents
| Cat. No. |
Product Name |
Target |
Research Areas |
Chemical Structure |
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- HY-P3443
-
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pNA
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Fluorescent Dye
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Others
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Peanut agglutinin (PNA) is a plant lectin that can be used as a probe to specifically bind biomolecules (such as polysaccharides, peptides, etc.).Peanut agglutinin (PNA) is a biological material or organic compound that can be used in life science research .
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-
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- HY-NP0138
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pNA (Fluorescein)
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Fluorescent Dye
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Others
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Peanut Agglutinin (PNA) Fluorescein is a plant lectin that can be used as a probe to specifically bind biomolecules (such as polysaccharides, peptides, etc.).Peanut Agglutinin (PNA) Fluorescein is a biological material or organic compound that can be used in life science research .
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-
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- HY-NP0182
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pNA (Biotinylated)
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Fluorescent Dye
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Others
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Peanut Agglutinin (PNA) Biotinylated is a plant lectin that can be used as a probe to specifically bind biomolecules (such as polysaccharides, peptides, etc.).Peanut Agglutinin (PNA) Biotinylated is a biological material or organic compound that can be used in life science research .
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- HY-NP0156
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pNA (Rhodamine)
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Fluorescent Dye
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Others
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Peanut Agglutinin (PNA) Rhodamine is a plant lectin that can be used as a probe to specifically bind biomolecules (such as polysaccharides, peptides, etc.).Peanut Agglutinin (PNA) Rhodamine is a biological material or organic compound that can be used in life science research .
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-
-
- HY-P4581
-
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Suc-ALPF-pNA
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FKBP
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Others
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Suc-Ala-Leu-Pro-Phe-pNA (Suc-ALPF-pNA) is a substrate of FK-506 binding protein (FKBP) .
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-
-
- HY-NP0165
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pNA (Agarose)
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Fluorescent Dye
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Others
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Peanut Agglutinin (PNA) Agarose is a plant lectin that can be used as a probe to specifically bind biomolecules (such as polysaccharides, peptides, etc.).Peanut Agglutinin (PNA) Agarose is a biological material or organic compound that can be used in life science research .
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- HY-NP093
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pNA (CY3)
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Fluorescent Dye
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Others
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Peanut Agglutinin (PNA) CY3 is a plant lectin that can be used as a probe to specifically bind biomolecules (such as polysaccharides, peptides, etc.).Peanut Agglutinin (PNA) CY3 is a biological material or organic compound that can be used in life science research .
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-
-
- HY-P10001
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Z-Ile-Glu-Thr-Asp-pNA
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Caspase
|
Cancer
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Z-IETD-pNA (Z-Ile-Glu-Thr-Asp-pNA) is a colorimetric caspase-8 and granzyme B substrate. Z-IETD-pNA is hydrlyzed by caspase 8 to generate pNA .
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-
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- HY-P10084
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Caspase
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Others
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Ac-VAD-pNA is a caspase-1 substrate. Ac-VAD-pNA can be used to detect caspase-1 activity .
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-
-
- HY-W713878
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Caspase
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Others
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Ac-VDVAD-pNA is a caspase-2 substrate. Ac-VDVAD-pNA can be used to test the activity of caspase-2 .
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-
-
- HY-P2610
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Caspase
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Others
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Ac-VEID-pNA is an artificially synthesized peptide. Ac-VEID-pNA is utilized as substrate for caspase 6, that cleaves the lamin A at the cleavage site of VEID .
|
-
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- HY-137858
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Gly-Arg-4-NA hydrochloride; GR-pNA hydrochloride; GR p-itoailide hydrochloride
|
Fluorescent Dye
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Others
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H-Gly-Arg-pNA hydrochloride (GR-pNA hydrochloride) is a colorimetric substrate for thrombin. H-Gly-Arg-pNA is preferentially bound by thrombin and cleaves the Gly-Arg (GR) peptide sequence, releasing p-nitroaniline (pNA) that can be detected colorimetrically at 405 nm. H-Gly-Arg-pNA hydrochloride is used as a fluorescent dye to measure thrombin activity .
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-
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- HY-P4658
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Dipeptidyl Peptidase
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Others
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H-Val-Ala-pNA is a substrate for the dipeptide aminopeptidase (DPAPase) of Streptococcus bovis. H-Val-Ala-pNA can be used to measure the activity of the protease .
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-
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- HY-P10083
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-
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- HY-P4582
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Suc-FAAF-pNA
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Ser/Thr Protease
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Others
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Suc-Phe-Ala-Ala-Phe-pNA (Suc-FAAF-pNA) is a synthetic polypeptide that can serve as a substrate for the protease from Aeribacillus pallidus VP3 (SPVP), the serine alkaline protease from Caldicoprobacter guelmensis (SAPCG) strain D2C22 T, the alcalase ultra 2.5 L and the thermolsyin type X .
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- HY-P10005
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Ser/Thr Protease
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Cardiovascular Disease
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D-Val-Gly-Arg-pNA is a chromogenic substrate of TPA (tissue plasminogen activator). D-Val-Gly-Arg-pNA can be used to detect the amidolytic activity of TPA I and TPA II .
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- HY-P5027
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-
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- HY-P10236
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Caspase
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Others
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Ac-WEHD-pNA is a colorimetric substrate for caspase 1, 4, 5 and 14, which is utilized to measure the caspase activity .
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- HY-P4254
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PAI-1
Ser/Thr Protease
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Others
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H-Gly-Glu-pNA is a chromogenic peptide substrate that can be widely used in enzymatic analysis, including trypsin and urokinase-type plasminogen activator (uPA) .
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- HY-P4576
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Factor Xa
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Others
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Methoxycarbonyl-D-Nle-Gly-Arg-pNA is a synthetic trypsin that can serve as a substrate for coagulation factors IXa (FIXa) and Xa (FXa) .
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- HY-P2630
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Interleukin Related
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Inflammation/Immunology
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Suc-YVAD-pNA is a substrate of ICE. Interleukin-1β-converting enzyme (ICE) is a cysteine protease responsible for the cleavage of pre-interleukin-1β (pre-IL-1β) to the mature cytokine and a member of a family of related proteases (the caspases) .
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- HY-P0021
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Chromozym Pca
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Fluorescent Dye
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Others
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D-Lys(Z)-Pro-Arg-pNA (Chromozym Pca) is a chromogenic peptide substrate of activated protein C (APC) .
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- HY-126809A
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Bz-PFR-pNA hydrochloride
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Factor Xa
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Others
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Bz-Pro-Phe-Arg-pNA (Bz-PFR-pNA) hydrochloride is a chromogenic peptide substrate for plasma and glandular Kallikrein, cysteine proteinase (Cruzipain) and Trypsin. Bz-Pro-Phe-Arg-pNA hydrochloride can be used in Factor XII assay .
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- HY-126809
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Bz-PFR-pNA
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Kallikrein
Ser/Thr Protease
Parasite
Factor Xa
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Others
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Bz-Pro-Phe-Arg-pNA (Bz-PFR-pNA) is a chromogenic peptide substrate for plasma and glandular Kallikrein, cysteine proteinase (Cruzipain) and Trypsin. Bz-Pro-Phe-Arg-pNA can be used in Factor XII assay .
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- HY-P5974
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Z-Tyr-Val-Ala-Asp-pNA
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Caspase
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Others
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Z-YVAD-pNA (Z-Tyr-Val-Ala-Asp-pNA) is a caspase-1 substrate .
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- HY-P4460
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Ser/Thr Protease
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Cancer
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AAA-pNA is a chromogenic substrate of Tripeptidyl-peptidase II. AAA-pNA can be used to test Tripeptidyl-peptidase II activity .
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- HY-P10666
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Caspase
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Others
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Ac-VDQQD-pNA is a substrate of Caspase 2 and can be cleaved to produce yellow pNA (p-nitroaniline) .
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- HY-P4458
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Ser/Thr Protease
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Cancer
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Boc-QAR-pNA is a chromogenic substrate of trypsin. Boc-QAR-pNA can be used to test trypsin activity .
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-
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- HY-P4476
-
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Ser/Thr Protease
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Others
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Suc-AAPA-pNA is a substrate of chymotrypsin Aα. Suc-AAPA-pNA can be used to test chymotrypsin Aα activity .
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- HY-P4482
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Bacterial
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Infection
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Suc-AAPE-pNA is a chromogenic substrate of glutamyl endopeptidase. Suc-AAPE-pNA can be used to test glutamyl endopeptidase activity .
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- HY-P4455
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Bacterial
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Infection
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Boc-AAG-pNA is a glycine endopeptidase substrate. Boc-AAG-pNA can be used to test the amidase activity glycine endopeptidase .
|
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- HY-P4202
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Suc-AEPF-pNA
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Biochemical Assay Reagents
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Others
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Suc-Ala-Glu-Pro-Phe-pNA (Suc-AEPF-pNA) is a chromogenic substrate for the peptidylprolyl isomerase Pin1. Suc-Ala-Glu-Pro-Phe-pNA can be used to evaluate the inhibitory effect of the target compound on Pin1, and catalytic activity of Pin1, etc .
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- HY-119244
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Dipeptidyl Peptidase
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Metabolic Disease
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Gly-Pro-pNA hydrochloride is a chromogenic substrate that can be cleaved by the circulating enzyme, dipeptidyl peptidase IV (DPP IV). Gly-Pro-pNA can be used to screen for DPP IV inhibitors. Gly-Pro-pNA hydrochloride can be studied as an experimental antidiabetic agents .
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- HY-P4477
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Ser/Thr Protease
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Others
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Suc-AAPR-pNA is a substrate of trypsin acyl-enzymes. Suc-AAPR-pNA can be used to test trypsin acyl-enzymes activity .
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- HY-125128
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-
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- HY-P10161
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Biochemical Assay Reagents
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Others
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Ac-DMQD-pNA is a peptide substrate. Both of the recombinant CgCaspase-1 (rCgCaspase-1) and the C-terminus of CgCaspase-1 (rCgCaspase-1-C) exhibits similar caspase activity towards proteolytic substrate Ac-DMQD-pNA and Ac-DEVD-pNA (HY-P1006) .
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- HY-P4202A
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Suc-AEPF-pNA TFA
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Biochemical Assay Reagents
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Others
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Suc-Ala-Glu-Pro-Phe-pNA (Suc-AEPF-pNA ) TFA is a chromogenic substrate for the peptidylprolyl isomerase Pin1. Suc-Ala-Glu-Pro-Phe-pNA TFA can be used to evaluate the inhibitory effect of the target compound on Pin1, and catalytic activity of Pin1, etc .
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- HY-114150D
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Kallikrein
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Others
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D-Val-Leu-Arg-pNA (acetate) is the acetate form of D-Pro-Phe-Arg-p-nitroanilide (pNa). D-Pro-Phe-Arg-p-nitroanilide (pNa) is the substrate for kallikrein and can be used to assay the activity of kallikrein .
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- HY-P4464
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Ser/Thr Protease
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Cancer
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Ala-Phe-Pro-pNA is a chromogenic substrate of tripeptidyl peptidase. Ala-Phe-Pro-pNA can be used to test tripeptidyl peptidase activity .
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- HY-P4470
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Ser/Thr Protease
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Cancer
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Phe-Pro-Ala-pNA is a chromogenic substrate of tripeptidyl peptidase. Phe-Pro-Ala-pNA can be used to test tripeptidyl peptidase activity .
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- HY-P10448
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- HY-W011701
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- HY-P4475
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- HY-P2091
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Caspase
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Inflammation/Immunology
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Ac-YVAD-pNA is a specific Caspase-1 substrate. Ac-YVAD-pNA can be used to detect Caspase-1 activity. Caspase-1 is a key mediator of inflammatory processes .
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- HY-131409
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D-Val-Leu-Lys-p-itoailide dihydrochloride; D-VLK-pNA dihydrochloride; S 2251 dihydrochloride
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Fluorescent Dye
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Others
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D-Val-Leu-Lys-pNA dihydrochloride (D-VLK-pNA dihydrochloride) is a colorimetric substrate for plasminolytic activity. D-Val-Leu-Lys-pNA dihydrochloride is catalytically bound and hydrolyzed by plasmin to release p-nitroaniline (pNA), which can be detected colorimetrically at 405 nm as a measure of plasminolytic activity .
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- HY-P10094
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Fluorescent Dye
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Others
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β-Ala-Gly-Arg-pNA is a chromogenic substrate of thrombin with pNA a strong absorbance at 405 nm .
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- HY-P6027A
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Fluorescent Dye
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Others
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H-D-CHA-Ala-Arg-pNA diacetate is the diacetate form of H-D-CHA-Ala-Arg-pNA (HY-P6027). H-D-CHA-Ala-Arg-pNA diacetate is a chromogenic substrate for the amidolytic assay .
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- HY-P4518
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Ser/Thr Protease
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Others
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Z-Val-Gly-Arg-pNA is a chromogenic substrate for urokinase. Z-Val-Gly-Arg-pNA can be used for determination of urokinase activity .
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- HY-W747366
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- HY-P4465
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Fluorescent Dye
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Others
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Gly-Arg-pNA is a fluorogenic substrate for the measurement of protease activity. Gly-Arg-pNA undergoes hydrolysis and releases the fluorescent product p-nitroaniline. p-nitroaniline is in a fluorescent state under ultraviolet light irradiation and can emit a fluorescent signal .
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- HY-P4464A
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Ser/Thr Protease
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Cancer
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Ala-Phe-Pro-pNA TFA is a chromogenic substrate of tripeptidyl peptidase. Ala-Phe-Pro-pNA TFA can be used to test tripeptidyl peptidase activity .
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- HY-P4453
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Caspase
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Cancer
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Boc-Ala-Ala-Asp-pNA is a chromogenic substrate of granzyme B. Boc-Ala-Ala-Asp-pNA can be used to test functional activity of granzyme B .
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- HY-P4515
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- HY-P4706
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- HY-147167
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- HY-148415
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- HY-P4468
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- HY-P1006
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Caspase
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Others
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Ac-DEVD-pNA is a ligand for caspase-3/-7 and related cysteine proteases .
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- HY-W010783
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- HY-P4484
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Biochemical Assay Reagents
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Others
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Suc-AAPK-pNA is a chromogenic substrate for the determination of serine/threonine kinase activity and enzyme kinetic parameters .
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- HY-138152
-
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Benzyl-D-Arg-Gly-Arg-pNA dihydrochloride
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Fluorescent Dye
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Others
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Z-D-Arg-Gly-Arg-pNA dihydrochloride is a hydrolytic chromogenic plasmin substrate .
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- HY-P3118
-
-
- HY-122142
-
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S-2366
|
APC
Factor XI
Biochemical Assay Reagents
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Others
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Pyr-Pro-Arg-pNA (S2366) is a chromogenic peptide substrate for Factor XI and Activated protein C (APC). Pyr-Pro-Arg-pNA can induce noncompetitive inhibition of factor XI activation through occupancy of the active site of the factor XIa-light chain. Pyr-Pro-Arg-pNA can be used for measurement of APC amidolytic activity .
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- HY-122142A
-
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S-2366 hydrochloride
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APC
Factor XI
Biochemical Assay Reagents
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Others
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Pyr-Pro-Arg-pNA (S2366) hydrochloride is a chromogenic peptide substrate for Factor XI and Activated protein C (APC). Pyr-Pro-Arg-pNA hydrochloride can induce noncompetitive inhibition of factor XI activation through occupancy of the active site of the factor XIa-light chain. Pyr-Pro-Arg-pNA hydrochloride can be used for measurement of APC amidolytic activity .
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- HY-137220
-
-
- HY-P10145
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-
- HY-P4500
-
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Cathepsin
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Others
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Z-Arg-Arg-pNA is a substrate for cathepsin B and can be used to detect this enzyme activity .
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- HY-148372
-
-
- HY-P4490
-
-
- HY-P10668
-
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Dengue Virus
Flavivirus
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Infection
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Ac-EVKKQR-pNA is a competitive chromogenic para-nitroanilide substrate corresponding to the P6-P1 segment amino-terminal to the NS2B-NS3 cleavage site but with a more reactive, hydrolytically cleavable, para-nitroanilide at the P1’ position. Ac-EVKKQR-pNA is promising for research of dengue 2 virus and flavivirus virus infection .
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- HY-137186
-
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Proteasome
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Others
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Suc-Gly-Gly-Phe-pNA is the chymotrypsin substrate with an Km value of 1.6 mM .
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- HY-P6027
-
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Thrombin
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Others
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H-D-CHA-Ala-Arg-pNA is a chromogenic substrate for the amidolytic assay .
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-
- HY-P4494
-
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Cathepsin
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Others
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Suc-Val-Pro-Phe-pNA is a substrate for cathepsin G and can be used to detect the activity of this enzyme .
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- HY-W540122
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-
- HY-P4496
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Phosphatase
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Others
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Tos-Gly-Pro-Lys-pNA is a substrate for the serine protease ALP and can be used to measure the activity of this enzyme .
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- HY-W338079
-
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Caspase
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Others
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Ac-Asp-Glu-Val-Asp-pNA is a peptidic substrate of caspase-3/7 .
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- HY-168378
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-
- HY-123275C
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S-2238 dihydrochloride
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Fluorescent Dye
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Others
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H-D-Phe-Pip-Arg-pNA (S-2238) dihydrochloride, a chromogenic substrate, is patterned after the N-terminal portion of the A alpha chain of fibrinogen, which is the natural substrate of thrombin. H-D-Phe-Pip-Arg-pNA dihydrochloride is specific for thrombin and is used to measure antithrombin-heparin cofactor (AT-III). The AT-III assay using H-D-Phe-Pip-Arg-pNA dihydrochloride is sensitive, accurate, and easy to perform .
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- HY-123275A
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S-2238 hydrochloride
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Fluorescent Dye
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Others
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H-D-Phe-Pip-Arg-pNA (S-2238) hydrochloride, a chromogenic substrate, is patterned after the N-terminal portion of the A alpha chain of fibrinogen, which is the natural substrate of thrombin. H-D-Phe-Pip-Arg-pNA hydrochloride is specific for thrombin and is used to measure antithrombin-heparin cofactor (AT-III). The AT-III assay using H-D-Phe-Pip-Arg-pNA hydrochloride is sensitive, accurate, and easy to perform .
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- HY-123275B
-
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S-2238 acetate
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Fluorescent Dye
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Others
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H-D-Phe-Pip-Arg-pNA (S-2238) acetate, a chromogenic substrate, is patterned after the N-terminal portion of the A alpha chain of fibrinogen, which is the natural substrate of thrombin. H-D-Phe-Pip-Arg-pNA acetate is specific for thrombin and is used to measure antithrombin-heparin cofactor (AT-III). The AT-III assay using H-D-Phe-Pip-Arg-pNA acetate is sensitive, accurate, and easy to perform .
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- HY-123275
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S-2238
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Fluorescent Dye
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Others
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H-D-Phe-Pip-Arg-pNA (S-2238), a chromogenic substrate, is patterned after the N-terminal portion of the A alpha chain of fibrinogen, which is the natural substrate of thrombin. H-D-Phe-Pip-Arg-pNA is specific for thrombin and is used to measure antithrombin-heparin cofactor (AT-III). The AT-III assay using H-D-Phe-Pip-Arg-pNA is sensitive, accurate, and easy to perform .
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- HY-W011155
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-
- HY-P4039
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HCV Protease
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Infection
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Ac-EEVVAC-pNA is a chromogenic substrate for a continuous spectrophotometric assay of HCV NS3 protease. The sequence EEVVAC is derived from the 5A-5B cleavage junction of the HCV polyprotein .
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- HY-P4772
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- HY-P2685
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Fluorescent Dye
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Others
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MeOSuc-Ala-Ala-Pro-Val-pNA is a sensitive chromogenic substrate for human leukocyte and porcine pancreatic elastase .
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- HY-P3794
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-
- HY-P4462
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Ser/Thr Protease
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Others
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D-Leu-Thr-Arg-pNA is a substrate for γ-Tryptase, and can be used to measure the effects of small molecule inhibitors on γ-Tryptase activity .
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-
- HY-114150
-
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PAI-1
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Others
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D-Val-Leu-Arg-pNA is a glandular kininoreleasing enzyme substrate that also acts as a substrate for tissue-type plasminogen activator (t-PA) with no apparent affinity for fibrin .
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- HY-P5376
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S-2586
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Ser/Thr Protease
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Others
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MeOSuc-Arg-Pro-Tyr-pNA (S-2586) is a biological active peptide. (chymotrypsin substrate)
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- HY-P3126
-
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Factor Xa
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Others
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Suc-Ile-Glu(γ-pip)-Gly-Arg-pNA hydrochloride is a factor Xa specific chromogenic substrate .
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- HY-126785
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Colorimetric Elastase Substrate
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Elastase
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Others
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Suc-AAP-Abu-pNA (Colorimetric Elastase Substrate) is a specific substrate for pancreatic elastase (Km = 100 μM; Kcat/Km = 35,300 s -1 M -1 for rat pancreatic elastase; Km = 30 μM; Kcat/Km = 351,000 s -1 M -1 for porcine pancreatic elastase). Suc-AAP-Abu-pNA also promotes OPC migration .
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- HY-153829
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-
- HY-138143
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Chromozym-TH
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Fluorescent Dye
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Others
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N-(p-Tosyl)-GPR-pNA acetate (Chromozym-TH) is a chromogenic substrate targeting the synthetic peptides Hirunorm IV and Hirunorm V and can be used to detect the dissociation constants (KI) of both peptides. Hirunorm IV and Hirunorm V are reversible inhibitors of amidolytic thrombin activity. By varying the peptide concentration at a fixed concentration of the chromogenic substrate N-(p-Tosyl)-GPR-pNA acetate, the dissociation constants determined were 0.134 nM (Hirunorm IV) and 0.245 nM (Hirunorm V) .
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- HY-P0021A
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Spectrozyme PCa; Chromozym Pca diacetate
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Fluorescent Dye
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Others
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D-Lys(Z)-Pro-Arg-pNA diacetate is a chromogenic peptide substrate of activated protein C (APC) .
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-
- HY-P2648
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N-Succinyl-AAPL-p-nitroanilide
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Biochemical Assay Reagents
|
|
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Suc-Ala-Ala-Pro-Leu-pNA (N-Succinyl-AAPL-p-nitroanilide) is a biochemical reagent .
|
-
- HY-137895
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H-Arg-pNA 2HCl, 98%
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Biochemical Assay Reagents
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Others
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L-Arginine p-nitroanilide dihydrochloride, 98% (H-Arg-pNA 2HCl, 98%) is a chromogenic substrate for cathepsin H and aminopeptidases.
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- HY-120833
-
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Caspase
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Others
|
|
Ac-Ile-Glu-Thr-Asp-pNA is a substrate for caspase-8. Caspase-8 binds to and cleaves the Ile-Glu-Thr-Asp (IETD) peptide sequence to release p-nitroalinide, which can be quantified by colorimetric detection at 405 nm as a measure of enzyme activity .
|
-
- HY-P3236
-
|
Ac-IEPD-pNA
|
Fluorescent Dye
|
Cancer
|
|
N-Acetyl-Ile-Glu-Pro-Asp-p-nitroanilide (Ac-IEPD-pNA) is a colorimetric peptide substrate of granzyme B that allows accurate measurement of granzyme B activity .
|
-
- HY-151778
-
|
|
ADC Linker
|
Others
|
|
Fmoc-Abg(N3)-OH is a click chemistry reagent containing an azide group. Fmoc-Abg(N3)-OH has the potential to synthesize peptide nucleic acids (PNA) and peptoids. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
|
-
- HY-P3480
-
|
|
Fluorescent Dye
|
Others
|
|
H-Trp-Phe-Tyr-Ser(PO3H2)-Pro-Arg-pNA is a chromogenic substrate for Pin1. Pin1 is an essential and conserved mitotic peptidyl-prolyl isomerase, and can recognize the phosphoserine-proline bonds present in mitotic phosphoproteins .
|
-
- HY-108409
-
|
Etienic acid; Testosterone-17β-carboxylic acid; 3-Oxoandrost-4-ene-17β-carboxylic acid
|
Drug Derivative
|
Metabolic Disease
Cancer
|
|
Progesterone carboxylic acid (Testosterone-17β-carboxylic acid) is an androstenedione analogue. Progesterone carboxylic acid can conjugate with 20-mer peptide nucleic acid (PNA) and the conjugate has superior binding capacity on complementary DNA. Progesterone carboxylic acid can be used for cancers and type 2 diabetes (T2D) research .
|
-
- HY-151738
-
|
|
ADC Linker
|
Others
|
|
Fmoc-Aeg(N3)-OH is a click chemistry reagent containing an Azide. Alkylating the Nitrogen of an amide bond results in peptoid structures, which leads to conformational restrains, like N-methylation and allows backbone derivatisation. Altering cytotoxicity, bacterial cell selectivity and receptor pharmacology through formation of peptoid derivatives have been published for Cilengitide, Piscidin 1, and MC3, MC4 and MC5 receptor agonist. This building block enables design of macrocycles through intermolecular crosslinking or backbone stabilization through intermolecular ring-closure. This compound is a potential building block for the construction of (customized) peptide nucleic acids (PNAs) and for peptoid synthesis . Fmoc-Aeg(N3)-OH is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-P3936
-
|
|
Fluorescent Dye
|
Others
|
|
Endotoxin Substrate (Boc-LGR-pNA) is a chromogenic substrate can be used in quantitative assays of endotoxin .
|
-
- HY-P1347
-
-
- HY-P2664
-
|
Cathepsin G substrate
|
Biochemical Assay Reagents
|
Others
|
|
Cathepsin G substrate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-118959
-
|
Bz-Phe-Val-Arg-pNA
|
Cathepsin
|
Others
|
|
S2160 is a substrate of Cathepsin B that can be utilized in the calorimetric assay for the measurement of cathepsin B .
|
-
- HY-134445
-
-
- HY-137798
-
|
|
Fluorescent Dye
|
Others
|
|
Chromozym PL is a chromogenic substrate for plasmin, and the enzymatic reaction can be carried out in 0.1mL Tris-HCl buffer (50 mM, pH 7.8). 100 μM Chromozym PL was dissolved and prepared. After adding the hydrolase, the generation of p-nitroaniline (pNA) at 405 nm was continuously observed, and the hydrolysis products were calculated .
|
-
- HY-W718136
-
|
GlcN6P-Na
|
Biochemical Assay Reagents
|
Others
|
|
D-Glucosamine 6-phosphate (sodium) (GlcN6P-Na) is a class of biochemical reagents used in glycobiology research. Glycobiology studies the structure, synthesis, biology, and evolution of sugars. It involves carbohydrate chemistry, enzymology of glycan formation and degradation, protein-glycan recognition, and the role of glycans in biological systems. This field is closely related to basic research, biomedicine, and biotechnology .
|
-
- HY-120482
-
|
|
Microtubule/Tubulin
|
Others
|
|
CHM-1-P-Na is a sodium monophosphate salt of 2-(2-fluorophenyl)-6,7-methylenedioxyquinolin-4-one, which can be converted into CHM-1, a compound with a unique anti-tumor mechanism, in vitro and in vivo, and has excellent anti-tumor activity in tumor models and clear pharmacological effects on related enzymes.
|
-
- HY-137901
-
|
Ala-4-nitroanilide, 99%; H-Ala-pNA, 99%
|
Biochemical Assay Reagents
|
Others
|
|
L-Alanine 4-nitroanilide hydrochloride, 99% is a detection substrate for L-alanine aminopeptidase.
|
-
- HY-W008129
-
|
|
Endogenous Metabolite
|
Infection
|
|
H-D-cis-Hyp-OH (cis-4-Hydroxy-D-proline) is a proline derivative involved in bacterial metabolic pathways and is a substrate for cis-4-hydroxy-D-proline dehydrogenase. H-D-cis-Hyp-OH is a precursor for the synthesis of conformationally constrained PNA adenine monomers and can be used to study the specificity and kinetics of D-alanine dehydrogenase .
|
-
- HY-W008129R
-
|
|
Endogenous Metabolite
|
Infection
|
|
H-D-cis-Hyp-OH (cis-4-Hydroxy-D-proline) is a proline derivative involved in bacterial metabolic pathways and is a substrate for cis-4-hydroxy-D-proline dehydrogenase. H-D-cis-Hyp-OH is a precursor for the synthesis of conformationally constrained PNA adenine monomers and can be used to study the specificity and kinetics of D-alanine dehydrogenase .
|
-
- HY-151828
-
|
|
ADC Linker
|
Others
|
|
N3-Gly-Aeg(Fmoc)-OH is a click chemistry reagent containing an azide group. PNA building-block that can be further modified using Click-chemistry . It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
|
-
| Cat. No. |
Product Name |
Type |
-
- HY-P4202
-
|
Suc-AEPF-pNA
|
Chromogenic Substrates
|
|
Suc-Ala-Glu-Pro-Phe-pNA (Suc-AEPF-pNA) is a chromogenic substrate for the peptidylprolyl isomerase Pin1. Suc-Ala-Glu-Pro-Phe-pNA can be used to evaluate the inhibitory effect of the target compound on Pin1, and catalytic activity of Pin1, etc .
|
-
- HY-131409
-
|
D-Val-Leu-Lys-p-itoailide dihydrochloride; D-VLK-pNA dihydrochloride; S 2251 dihydrochloride
|
Dyes
|
|
D-Val-Leu-Lys-pNA dihydrochloride (D-VLK-pNA dihydrochloride) is a colorimetric substrate for plasminolytic activity. D-Val-Leu-Lys-pNA dihydrochloride is catalytically bound and hydrolyzed by plasmin to release p-nitroaniline (pNA), which can be detected colorimetrically at 405 nm as a measure of plasminolytic activity .
|
-
- HY-P2685
-
|
|
Chromogenic Substrates
|
|
MeOSuc-Ala-Ala-Pro-Val-pNA is a sensitive chromogenic substrate for human leukocyte and porcine pancreatic elastase .
|
-
- HY-P0021A
-
|
Spectrozyme PCa; Chromozym Pca diacetate
|
Chromogenic Substrates
|
|
D-Lys(Z)-Pro-Arg-pNA diacetate is a chromogenic peptide substrate of activated protein C (APC) .
|
-
- HY-P3236
-
|
Ac-IEPD-pNA
|
Fluorescent Dyes/Probes
|
|
N-Acetyl-Ile-Glu-Pro-Asp-p-nitroanilide (Ac-IEPD-pNA) is a colorimetric peptide substrate of granzyme B that allows accurate measurement of granzyme B activity .
|
-
- HY-137858
-
|
Gly-Arg-4-NA hydrochloride; GR-pNA hydrochloride; GR p-itoailide hydrochloride
|
Dyes
|
|
H-Gly-Arg-pNA hydrochloride (GR-pNA hydrochloride) is a colorimetric substrate for thrombin. H-Gly-Arg-pNA is preferentially bound by thrombin and cleaves the Gly-Arg (GR) peptide sequence, releasing p-nitroaniline (pNA) that can be detected colorimetrically at 405 nm. H-Gly-Arg-pNA hydrochloride is used as a fluorescent dye to measure thrombin activity .
|
-
- HY-P0021
-
|
Chromozym Pca
|
Chromogenic Substrates
|
|
D-Lys(Z)-Pro-Arg-pNA (Chromozym Pca) is a chromogenic peptide substrate of activated protein C (APC) .
|
-
- HY-P4202A
-
|
Suc-AEPF-pNA TFA
|
Chromogenic Substrates
|
|
Suc-Ala-Glu-Pro-Phe-pNA (Suc-AEPF-pNA ) TFA is a chromogenic substrate for the peptidylprolyl isomerase Pin1. Suc-Ala-Glu-Pro-Phe-pNA TFA can be used to evaluate the inhibitory effect of the target compound on Pin1, and catalytic activity of Pin1, etc .
|
-
- HY-W338079
-
-
- HY-P4039
-
|
|
Chromogenic Substrates
|
|
Ac-EEVVAC-pNA is a chromogenic substrate for a continuous spectrophotometric assay of HCV NS3 protease. The sequence EEVVAC is derived from the 5A-5B cleavage junction of the HCV polyprotein .
|
| Cat. No. |
Product Name |
Type |
-
- HY-P3443
-
|
pNA
|
Native Proteins
|
|
Peanut agglutinin (PNA) is a plant lectin that can be used as a probe to specifically bind biomolecules (such as polysaccharides, peptides, etc.).Peanut agglutinin (PNA) is a biological material or organic compound that can be used in life science research .
|
-
- HY-NP0138
-
|
pNA (Fluorescein)
|
Native Proteins
|
|
Peanut Agglutinin (PNA) Fluorescein is a plant lectin that can be used as a probe to specifically bind biomolecules (such as polysaccharides, peptides, etc.).Peanut Agglutinin (PNA) Fluorescein is a biological material or organic compound that can be used in life science research .
|
-
- HY-NP0182
-
|
pNA (Biotinylated)
|
Native Proteins
|
|
Peanut Agglutinin (PNA) Biotinylated is a plant lectin that can be used as a probe to specifically bind biomolecules (such as polysaccharides, peptides, etc.).Peanut Agglutinin (PNA) Biotinylated is a biological material or organic compound that can be used in life science research .
|
-
- HY-NP0156
-
|
pNA (Rhodamine)
|
Native Proteins
|
|
Peanut Agglutinin (PNA) Rhodamine is a plant lectin that can be used as a probe to specifically bind biomolecules (such as polysaccharides, peptides, etc.).Peanut Agglutinin (PNA) Rhodamine is a biological material or organic compound that can be used in life science research .
|
-
- HY-137895
-
|
H-Arg-pNA 2HCl, 98%
|
Enzyme Substrates
|
|
L-Arginine p-nitroanilide dihydrochloride, 98% (H-Arg-pNA 2HCl, 98%) is a chromogenic substrate for cathepsin H and aminopeptidases.
|
-
- HY-P2664
-
|
Cathepsin G substrate
|
Biochemical Assay Reagents
|
|
Cathepsin G substrate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-NP0165
-
|
pNA (Agarose)
|
Native Proteins
|
|
Peanut Agglutinin (PNA) Agarose is a plant lectin that can be used as a probe to specifically bind biomolecules (such as polysaccharides, peptides, etc.).Peanut Agglutinin (PNA) Agarose is a biological material or organic compound that can be used in life science research .
|
-
- HY-NP093
-
|
pNA (CY3)
|
Native Proteins
|
|
Peanut Agglutinin (PNA) CY3 is a plant lectin that can be used as a probe to specifically bind biomolecules (such as polysaccharides, peptides, etc.).Peanut Agglutinin (PNA) CY3 is a biological material or organic compound that can be used in life science research .
|
-
- HY-W747366
-
-
- HY-W010783
-
-
- HY-W718136
-
|
GlcN6P-Na
|
Carbohydrates
|
|
D-Glucosamine 6-phosphate (sodium) (GlcN6P-Na) is a class of biochemical reagents used in glycobiology research. Glycobiology studies the structure, synthesis, biology, and evolution of sugars. It involves carbohydrate chemistry, enzymology of glycan formation and degradation, protein-glycan recognition, and the role of glycans in biological systems. This field is closely related to basic research, biomedicine, and biotechnology .
|
-
- HY-137901
-
|
Ala-4-nitroanilide, 99%; H-Ala-pNA, 99%
|
Carbohydrates
|
|
L-Alanine 4-nitroanilide hydrochloride, 99% is a detection substrate for L-alanine aminopeptidase.
|
| Cat. No. |
Product Name |
Target |
Research Area |
-
- HY-P4581
-
|
Suc-ALPF-pNA
|
FKBP
|
Others
|
|
Suc-Ala-Leu-Pro-Phe-pNA (Suc-ALPF-pNA) is a substrate of FK-506 binding protein (FKBP) .
|
-
- HY-P2573
-
|
Suc-Ala-Ala-Pro-Phe-pNA
|
Peptides
|
Others
|
|
Suc-AAPF-pNA (Suc-Ala-Ala-Pro-Phe-pNA) is a chromogenic p-nitroanilide (pNA) substrate with the Km of 1.7 mM. Cleavage of Suc-AAPF-pNA releases 4-nitroaniline, which is yellow in colour and can be measured spectrophotometrically. Suc-AAPF-pNA can be used for the measurement of free and membrane-bound cathepsin G in human neutrophils .
|
-
- HY-P10001
-
|
Z-Ile-Glu-Thr-Asp-pNA
|
Caspase
|
Cancer
|
|
Z-IETD-pNA (Z-Ile-Glu-Thr-Asp-pNA) is a colorimetric caspase-8 and granzyme B substrate. Z-IETD-pNA is hydrlyzed by caspase 8 to generate pNA .
|
-
- HY-P10084
-
|
|
Caspase
|
Others
|
|
Ac-VAD-pNA is a caspase-1 substrate. Ac-VAD-pNA can be used to detect caspase-1 activity .
|
-
- HY-W713878
-
|
|
Caspase
|
Others
|
|
Ac-VDVAD-pNA is a caspase-2 substrate. Ac-VDVAD-pNA can be used to test the activity of caspase-2 .
|
-
- HY-P2610
-
|
|
Caspase
|
Others
|
|
Ac-VEID-pNA is an artificially synthesized peptide. Ac-VEID-pNA is utilized as substrate for caspase 6, that cleaves the lamin A at the cleavage site of VEID .
|
-
- HY-P4658
-
|
|
Dipeptidyl Peptidase
|
Others
|
|
H-Val-Ala-pNA is a substrate for the dipeptide aminopeptidase (DPAPase) of Streptococcus bovis. H-Val-Ala-pNA can be used to measure the activity of the protease .
|
-
- HY-P10083
-
-
- HY-P4582
-
|
Suc-FAAF-pNA
|
Ser/Thr Protease
|
Others
|
|
Suc-Phe-Ala-Ala-Phe-pNA (Suc-FAAF-pNA) is a synthetic polypeptide that can serve as a substrate for the protease from Aeribacillus pallidus VP3 (SPVP), the serine alkaline protease from Caldicoprobacter guelmensis (SAPCG) strain D2C22 T, the alcalase ultra 2.5 L and the thermolsyin type X .
|
-
- HY-P10005
-
|
|
Ser/Thr Protease
|
Cardiovascular Disease
|
|
D-Val-Gly-Arg-pNA is a chromogenic substrate of TPA (tissue plasminogen activator). D-Val-Gly-Arg-pNA can be used to detect the amidolytic activity of TPA I and TPA II .
|
-
- HY-P5027
-
-
- HY-P10236
-
|
|
Caspase
|
Others
|
|
Ac-WEHD-pNA is a colorimetric substrate for caspase 1, 4, 5 and 14, which is utilized to measure the caspase activity .
|
-
- HY-P4254
-
|
|
PAI-1
Ser/Thr Protease
|
Others
|
|
H-Gly-Glu-pNA is a chromogenic peptide substrate that can be widely used in enzymatic analysis, including trypsin and urokinase-type plasminogen activator (uPA) .
|
-
- HY-P4576
-
|
|
Factor Xa
|
Others
|
|
Methoxycarbonyl-D-Nle-Gly-Arg-pNA is a synthetic trypsin that can serve as a substrate for coagulation factors IXa (FIXa) and Xa (FXa) .
|
-
- HY-P2630
-
|
|
Interleukin Related
|
Inflammation/Immunology
|
|
Suc-YVAD-pNA is a substrate of ICE. Interleukin-1β-converting enzyme (ICE) is a cysteine protease responsible for the cleavage of pre-interleukin-1β (pre-IL-1β) to the mature cytokine and a member of a family of related proteases (the caspases) .
|
-
- HY-P0021
-
|
Chromozym Pca
|
Fluorescent Dye
|
Others
|
|
D-Lys(Z)-Pro-Arg-pNA (Chromozym Pca) is a chromogenic peptide substrate of activated protein C (APC) .
|
-
- HY-P5348
-
|
|
Peptides
|
Others
|
|
Ac-LEHD-pNA is a biological active peptide. (Caspase-9 substrate; pNA (4-nitroaniline)-derived caspase substrates are widely used for the colorimetric detection of various caspase activities. Cleavage of pNA peptides by caspases generates pNA that is monitored colorimetrically at ~405 nm. pNA has maximum absorption around 408 nm.)
|
-
- HY-126809A
-
|
Bz-PFR-pNA hydrochloride
|
Factor Xa
|
Others
|
|
Bz-Pro-Phe-Arg-pNA (Bz-PFR-pNA) hydrochloride is a chromogenic peptide substrate for plasma and glandular Kallikrein, cysteine proteinase (Cruzipain) and Trypsin. Bz-Pro-Phe-Arg-pNA hydrochloride can be used in Factor XII assay .
|
-
- HY-126809
-
|
Bz-PFR-pNA
|
Kallikrein
Ser/Thr Protease
Parasite
Factor Xa
|
Others
|
|
Bz-Pro-Phe-Arg-pNA (Bz-PFR-pNA) is a chromogenic peptide substrate for plasma and glandular Kallikrein, cysteine proteinase (Cruzipain) and Trypsin. Bz-Pro-Phe-Arg-pNA can be used in Factor XII assay .
|
-
- HY-P5974
-
|
Z-Tyr-Val-Ala-Asp-pNA
|
Caspase
|
Others
|
|
Z-YVAD-pNA (Z-Tyr-Val-Ala-Asp-pNA) is a caspase-1 substrate .
|
-
- HY-P4460
-
|
|
Ser/Thr Protease
|
Cancer
|
|
AAA-pNA is a chromogenic substrate of Tripeptidyl-peptidase II. AAA-pNA can be used to test Tripeptidyl-peptidase II activity .
|
-
- HY-P10666
-
|
|
Caspase
|
Others
|
|
Ac-VDQQD-pNA is a substrate of Caspase 2 and can be cleaved to produce yellow pNA (p-nitroaniline) .
|
-
- HY-P4461
-
|
|
Peptides
|
Others
|
|
Ala-Ala-Pro-pNA is a tripeptide, including chromophoric amino acids Pro-pNA. Ala-Ala-Pro-pNA is targeted by tripeptidyl aminopeptidase (SM-TAP) .
|
-
- HY-P4458
-
|
|
Ser/Thr Protease
|
Cancer
|
|
Boc-QAR-pNA is a chromogenic substrate of trypsin. Boc-QAR-pNA can be used to test trypsin activity .
|
-
- HY-P4476
-
|
|
Ser/Thr Protease
|
Others
|
|
Suc-AAPA-pNA is a substrate of chymotrypsin Aα. Suc-AAPA-pNA can be used to test chymotrypsin Aα activity .
|
-
- HY-P4482
-
|
|
Bacterial
|
Infection
|
|
Suc-AAPE-pNA is a chromogenic substrate of glutamyl endopeptidase. Suc-AAPE-pNA can be used to test glutamyl endopeptidase activity .
|
-
- HY-P4455
-
|
|
Bacterial
|
Infection
|
|
Boc-AAG-pNA is a glycine endopeptidase substrate. Boc-AAG-pNA can be used to test the amidase activity glycine endopeptidase .
|
-
- HY-P4202
-
|
Suc-AEPF-pNA
|
Biochemical Assay Reagents
|
Others
|
|
Suc-Ala-Glu-Pro-Phe-pNA (Suc-AEPF-pNA) is a chromogenic substrate for the peptidylprolyl isomerase Pin1. Suc-Ala-Glu-Pro-Phe-pNA can be used to evaluate the inhibitory effect of the target compound on Pin1, and catalytic activity of Pin1, etc .
|
-
- HY-P4477
-
|
|
Ser/Thr Protease
|
Others
|
|
Suc-AAPR-pNA is a substrate of trypsin acyl-enzymes. Suc-AAPR-pNA can be used to test trypsin acyl-enzymes activity .
|
-
- HY-125128
-
-
- HY-P10161
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Ac-DMQD-pNA is a peptide substrate. Both of the recombinant CgCaspase-1 (rCgCaspase-1) and the C-terminus of CgCaspase-1 (rCgCaspase-1-C) exhibits similar caspase activity towards proteolytic substrate Ac-DMQD-pNA and Ac-DEVD-pNA (HY-P1006) .
|
-
- HY-P4202A
-
|
Suc-AEPF-pNA TFA
|
Biochemical Assay Reagents
|
Others
|
|
Suc-Ala-Glu-Pro-Phe-pNA (Suc-AEPF-pNA ) TFA is a chromogenic substrate for the peptidylprolyl isomerase Pin1. Suc-Ala-Glu-Pro-Phe-pNA TFA can be used to evaluate the inhibitory effect of the target compound on Pin1, and catalytic activity of Pin1, etc .
|
-
- HY-114150D
-
|
|
Kallikrein
|
Others
|
|
D-Val-Leu-Arg-pNA (acetate) is the acetate form of D-Pro-Phe-Arg-p-nitroanilide (pNa). D-Pro-Phe-Arg-p-nitroanilide (pNa) is the substrate for kallikrein and can be used to assay the activity of kallikrein .
|
-
- HY-P4464
-
|
|
Ser/Thr Protease
|
Cancer
|
|
Ala-Phe-Pro-pNA is a chromogenic substrate of tripeptidyl peptidase. Ala-Phe-Pro-pNA can be used to test tripeptidyl peptidase activity .
|
-
- HY-P4470
-
|
|
Ser/Thr Protease
|
Cancer
|
|
Phe-Pro-Ala-pNA is a chromogenic substrate of tripeptidyl peptidase. Phe-Pro-Ala-pNA can be used to test tripeptidyl peptidase activity .
|
-
- HY-P10448
-
-
- HY-W011701
-
-
- HY-P4475
-
-
- HY-P2091
-
|
|
Caspase
|
Inflammation/Immunology
|
|
Ac-YVAD-pNA is a specific Caspase-1 substrate. Ac-YVAD-pNA can be used to detect Caspase-1 activity. Caspase-1 is a key mediator of inflammatory processes .
|
-
- HY-131409
-
|
D-Val-Leu-Lys-p-itoailide dihydrochloride; D-VLK-pNA dihydrochloride; S 2251 dihydrochloride
|
Fluorescent Dye
|
Others
|
|
D-Val-Leu-Lys-pNA dihydrochloride (D-VLK-pNA dihydrochloride) is a colorimetric substrate for plasminolytic activity. D-Val-Leu-Lys-pNA dihydrochloride is catalytically bound and hydrolyzed by plasmin to release p-nitroaniline (pNA), which can be detected colorimetrically at 405 nm as a measure of plasminolytic activity .
|
-
- HY-P10094
-
|
|
Fluorescent Dye
|
Others
|
|
β-Ala-Gly-Arg-pNA is a chromogenic substrate of thrombin with pNA a strong absorbance at 405 nm .
|
-
- HY-P6027A
-
|
|
Fluorescent Dye
|
Others
|
|
H-D-CHA-Ala-Arg-pNA diacetate is the diacetate form of H-D-CHA-Ala-Arg-pNA (HY-P6027). H-D-CHA-Ala-Arg-pNA diacetate is a chromogenic substrate for the amidolytic assay .
|
-
- HY-P4518
-
|
|
Ser/Thr Protease
|
Others
|
|
Z-Val-Gly-Arg-pNA is a chromogenic substrate for urokinase. Z-Val-Gly-Arg-pNA can be used for determination of urokinase activity .
|
-
- HY-134113
-
|
CBZ-Chromozym TH
|
Peptides
|
Others
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Z-Gly-Pro-Arg-pNA (z-GPR-pNA) is a photometric substrate in Prostate-Specific Antigen (PSA) activation protease assays. Z-Gly-Pro-Arg-pNA (z-GPR-pNA) can be used for the test of trypsin activity .
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-
- HY-P4465
-
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Fluorescent Dye
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Others
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Gly-Arg-pNA is a fluorogenic substrate for the measurement of protease activity. Gly-Arg-pNA undergoes hydrolysis and releases the fluorescent product p-nitroaniline. p-nitroaniline is in a fluorescent state under ultraviolet light irradiation and can emit a fluorescent signal .
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-
- HY-P4464A
-
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|
Ser/Thr Protease
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Cancer
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|
Ala-Phe-Pro-pNA TFA is a chromogenic substrate of tripeptidyl peptidase. Ala-Phe-Pro-pNA TFA can be used to test tripeptidyl peptidase activity .
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-
- HY-P4517
-
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Peptides
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Others
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Z-Tyr-Lys-Arg-pNA is a chromogenic substrate. Z-Tyr-Lys-Arg-pNA can be used to detect the activity of subtilisin-type and yapsin-like proteases .
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-
- HY-P4453
-
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|
Caspase
|
Cancer
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Boc-Ala-Ala-Asp-pNA is a chromogenic substrate of granzyme B. Boc-Ala-Ala-Asp-pNA can be used to test functional activity of granzyme B .
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-
- HY-P3939
-
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Peptides
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Others
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|
Suc-Ala-Ala-Pro-Trp-Pna is a peptide. Suc-Ala-Ala-Pro-Trp-pNA can be used for the research of various biochemical.
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-
- HY-P4515
-
- HY-P4706
-
- HY-P4516
-
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Peptides
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Cancer
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Z-Phe-Leu-Glu-pNA is a chromogenic substrate for glutamyl endopeptidases. Z-Phe-Leu-Glu-pNA has been used as a synthetic substrate in the study of proteolytic enzymes, including trypsin treatment, subtilisin and chymotrypsin. Z-Phe-Leu-Glu-pNA plays an important role in hormone disorders such as prostate cancer and breast cancer .
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- HY-P3938
-
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Peptides
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Others
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Suc-Ala-Ala-Pro-Gly-Pna is a peptide. Suc-Ala-Ala-Pro-Gly-pNA can be used for the research of various biochemical .
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- HY-P4489
-
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Peptides
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Others
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Suc-AAPM-pNA is a sensitive substrate for the determination of human pancreatic elastase activity .
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- HY-137409
-
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Peptides
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Others
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Suc-AAA-pNA?is the substrate of analysis of the reversible inhibition of porcine pancreatic elastase (PPE) .
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- HY-P4468
-
- HY-P1006
-
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Caspase
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Others
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Ac-DEVD-pNA is a ligand for caspase-3/-7 and related cysteine proteases .
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- HY-P4484
-
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Biochemical Assay Reagents
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Others
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Suc-AAPK-pNA is a chromogenic substrate for the determination of serine/threonine kinase activity and enzyme kinetic parameters .
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- HY-138152
-
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Benzyl-D-Arg-Gly-Arg-pNA dihydrochloride
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Fluorescent Dye
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Others
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Z-D-Arg-Gly-Arg-pNA dihydrochloride is a hydrolytic chromogenic plasmin substrate .
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- HY-P3118
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- HY-P4498
-
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Peptides
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Others
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|
Z-Ala-Pro-pNA is an endopeptidase substrate and can be used to detect the activity of this enzyme .
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- HY-P10145
-
- HY-P4500
-
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Cathepsin
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Others
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Z-Arg-Arg-pNA is a substrate for cathepsin B and can be used to detect this enzyme activity .
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- HY-P4343
-
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Peptides
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Others
|
|
Lys(Abz)-Pro-Pro-pNA is a fluorescent peptide substrate of PepP .
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- HY-P4490
-
- HY-P10668
-
|
|
Dengue Virus
Flavivirus
|
Infection
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|
Ac-EVKKQR-pNA is a competitive chromogenic para-nitroanilide substrate corresponding to the P6-P1 segment amino-terminal to the NS2B-NS3 cleavage site but with a more reactive, hydrolytically cleavable, para-nitroanilide at the P1’ position. Ac-EVKKQR-pNA is promising for research of dengue 2 virus and flavivirus virus infection .
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- HY-P4361
-
- HY-P4402
-
|
|
Peptides
|
Others
|
|
D-Ile-Phe-Lys-pNA is a highly specific substrate for human plasmin .
|
- HY-137186
-
|
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Proteasome
|
Others
|
|
Suc-Gly-Gly-Phe-pNA is the chymotrypsin substrate with an Km value of 1.6 mM .
|
- HY-P6027
-
|
|
Thrombin
|
Others
|
|
H-D-CHA-Ala-Arg-pNA is a chromogenic substrate for the amidolytic assay .
|
- HY-138109
-
|
|
Peptides
|
Others
|
|
D-Pro-Phe-Arg-pNA hydrochloride is the substrate for thrombin-like enzyme, with Km of 50.7 μM .
|
- HY-P4494
-
|
|
Cathepsin
|
Others
|
|
Suc-Val-Pro-Phe-pNA is a substrate for cathepsin G and can be used to detect the activity of this enzyme .
|
- HY-P4496
-
|
|
Phosphatase
|
Others
|
|
Tos-Gly-Pro-Lys-pNA is a substrate for the serine protease ALP and can be used to measure the activity of this enzyme .
|
- HY-123275C
-
|
S-2238 dihydrochloride
|
Fluorescent Dye
|
Others
|
|
H-D-Phe-Pip-Arg-pNA (S-2238) dihydrochloride, a chromogenic substrate, is patterned after the N-terminal portion of the A alpha chain of fibrinogen, which is the natural substrate of thrombin. H-D-Phe-Pip-Arg-pNA dihydrochloride is specific for thrombin and is used to measure antithrombin-heparin cofactor (AT-III). The AT-III assay using H-D-Phe-Pip-Arg-pNA dihydrochloride is sensitive, accurate, and easy to perform .
|
- HY-123275A
-
|
S-2238 hydrochloride
|
Fluorescent Dye
|
Others
|
|
H-D-Phe-Pip-Arg-pNA (S-2238) hydrochloride, a chromogenic substrate, is patterned after the N-terminal portion of the A alpha chain of fibrinogen, which is the natural substrate of thrombin. H-D-Phe-Pip-Arg-pNA hydrochloride is specific for thrombin and is used to measure antithrombin-heparin cofactor (AT-III). The AT-III assay using H-D-Phe-Pip-Arg-pNA hydrochloride is sensitive, accurate, and easy to perform .
|
- HY-123275B
-
|
S-2238 acetate
|
Fluorescent Dye
|
Others
|
|
H-D-Phe-Pip-Arg-pNA (S-2238) acetate, a chromogenic substrate, is patterned after the N-terminal portion of the A alpha chain of fibrinogen, which is the natural substrate of thrombin. H-D-Phe-Pip-Arg-pNA acetate is specific for thrombin and is used to measure antithrombin-heparin cofactor (AT-III). The AT-III assay using H-D-Phe-Pip-Arg-pNA acetate is sensitive, accurate, and easy to perform .
|
- HY-123275
-
|
S-2238
|
Fluorescent Dye
|
Others
|
|
H-D-Phe-Pip-Arg-pNA (S-2238), a chromogenic substrate, is patterned after the N-terminal portion of the A alpha chain of fibrinogen, which is the natural substrate of thrombin. H-D-Phe-Pip-Arg-pNA is specific for thrombin and is used to measure antithrombin-heparin cofactor (AT-III). The AT-III assay using H-D-Phe-Pip-Arg-pNA is sensitive, accurate, and easy to perform .
|
- HY-W011155
-
- HY-P4039
-
|
|
HCV Protease
|
Infection
|
|
Ac-EEVVAC-pNA is a chromogenic substrate for a continuous spectrophotometric assay of HCV NS3 protease. The sequence EEVVAC is derived from the 5A-5B cleavage junction of the HCV polyprotein .
|
- HY-P4772
-
- HY-P2685
-
|
|
Fluorescent Dye
|
Others
|
|
MeOSuc-Ala-Ala-Pro-Val-pNA is a sensitive chromogenic substrate for human leukocyte and porcine pancreatic elastase .
|
- HY-P3794
-
- HY-P4491
-
|
|
Peptides
|
Others
|
|
Suc-Leu-Leu-Val-Tyr-pNA is a chymotrypsin-like chromogenic substrate that can be used to detect chymotrypsin enzymatic activity .
|
- HY-P4462
-
|
|
Ser/Thr Protease
|
Others
|
|
D-Leu-Thr-Arg-pNA is a substrate for γ-Tryptase, and can be used to measure the effects of small molecule inhibitors on γ-Tryptase activity .
|
- HY-114150
-
|
|
PAI-1
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Others
|
|
D-Val-Leu-Arg-pNA is a glandular kininoreleasing enzyme substrate that also acts as a substrate for tissue-type plasminogen activator (t-PA) with no apparent affinity for fibrin .
|
- HY-P5376
-
|
S-2586
|
Ser/Thr Protease
|
Others
|
|
MeOSuc-Arg-Pro-Tyr-pNA (S-2586) is a biological active peptide. (chymotrypsin substrate)
|
- HY-P3126
-
|
|
Factor Xa
|
Others
|
|
Suc-Ile-Glu(γ-pip)-Gly-Arg-pNA hydrochloride is a factor Xa specific chromogenic substrate .
|
- HY-126785
-
|
Colorimetric Elastase Substrate
|
Elastase
|
Others
|
|
Suc-AAP-Abu-pNA (Colorimetric Elastase Substrate) is a specific substrate for pancreatic elastase (Km = 100 μM; Kcat/Km = 35,300 s -1 M -1 for rat pancreatic elastase; Km = 30 μM; Kcat/Km = 351,000 s -1 M -1 for porcine pancreatic elastase). Suc-AAP-Abu-pNA also promotes OPC migration .
|
- HY-P4921
-
|
|
Peptides
|
Others
|
|
Suc-Gly-Pro-pNA is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development .
|
- HY-P0021A
-
|
Spectrozyme PCa; Chromozym Pca diacetate
|
Fluorescent Dye
|
Others
|
|
D-Lys(Z)-Pro-Arg-pNA diacetate is a chromogenic peptide substrate of activated protein C (APC) .
|
- HY-P2648
-
|
N-Succinyl-AAPL-p-nitroanilide
|
Biochemical Assay Reagents
|
|
|
Suc-Ala-Ala-Pro-Leu-pNA (N-Succinyl-AAPL-p-nitroanilide) is a biochemical reagent .
|
- HY-120833
-
|
|
Caspase
|
Others
|
|
Ac-Ile-Glu-Thr-Asp-pNA is a substrate for caspase-8. Caspase-8 binds to and cleaves the Ile-Glu-Thr-Asp (IETD) peptide sequence to release p-nitroalinide, which can be quantified by colorimetric detection at 405 nm as a measure of enzyme activity .
|
- HY-P3236
-
|
Ac-IEPD-pNA
|
Fluorescent Dye
|
Cancer
|
|
N-Acetyl-Ile-Glu-Pro-Asp-p-nitroanilide (Ac-IEPD-pNA) is a colorimetric peptide substrate of granzyme B that allows accurate measurement of granzyme B activity .
|
- HY-P3480
-
|
|
Fluorescent Dye
|
Others
|
|
H-Trp-Phe-Tyr-Ser(PO3H2)-Pro-Arg-pNA is a chromogenic substrate for Pin1. Pin1 is an essential and conserved mitotic peptidyl-prolyl isomerase, and can recognize the phosphoserine-proline bonds present in mitotic phosphoproteins .
|
- HY-P3936
-
|
|
Fluorescent Dye
|
Others
|
|
Endotoxin Substrate (Boc-LGR-pNA) is a chromogenic substrate can be used in quantitative assays of endotoxin .
|
- HY-P4670
-
|
|
Peptides
|
Others
|
|
L-Valine p-nitroanilide is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development .
|
- HY-P5992
-
|
|
Peptides
|
Others
|
|
Factor VIIa substrate is a colorimetric substrate for Factor VIIa, that can be measured by absorbance at 405 nm .
|
- HY-P1347
-
- HY-P1347A
-
|
|
Peptides
|
Metabolic Disease
|
|
RETF-4NA TFA, a chymase-specific substrate, is a sensitive and selective substrate for chymase when free or bound to α2M .
|
- HY-P2664
-
|
Cathepsin G substrate
|
Biochemical Assay Reagents
|
Others
|
|
Cathepsin G substrate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
- HY-134445
-
- HY-P4084A
-
|
|
Peptides
|
Others
|
|
KLA seq acetate is a cell membrane-penetrating α-helical amphipathic model peptide. KLA seq acetate conjugates peptide nucleic acids (PNAs) for delivery to mammalian cells. KLA seq acetate covalently links targeted mRNA and fluorescein to form a delivery system that has low re-export and is less resistant to serum effects .
|
- HY-137798
-
|
|
Fluorescent Dye
|
Others
|
|
Chromozym PL is a chromogenic substrate for plasmin, and the enzymatic reaction can be carried out in 0.1mL Tris-HCl buffer (50 mM, pH 7.8). 100 μM Chromozym PL was dissolved and prepared. After adding the hydrolase, the generation of p-nitroaniline (pNA) at 405 nm was continuously observed, and the hydrolysis products were calculated .
|
| Cat. No. |
Product Name |
Category |
Target |
Chemical Structure |
| Cat. No. |
Product Name |
|
Classification |
-
- HY-151778
-
|
|
|
Azide
|
|
Fmoc-Abg(N3)-OH is a click chemistry reagent containing an azide group. Fmoc-Abg(N3)-OH has the potential to synthesize peptide nucleic acids (PNA) and peptoids. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
|
-
- HY-151738
-
|
|
|
Azide
|
|
Fmoc-Aeg(N3)-OH is a click chemistry reagent containing an Azide. Alkylating the Nitrogen of an amide bond results in peptoid structures, which leads to conformational restrains, like N-methylation and allows backbone derivatisation. Altering cytotoxicity, bacterial cell selectivity and receptor pharmacology through formation of peptoid derivatives have been published for Cilengitide, Piscidin 1, and MC3, MC4 and MC5 receptor agonist. This building block enables design of macrocycles through intermolecular crosslinking or backbone stabilization through intermolecular ring-closure. This compound is a potential building block for the construction of (customized) peptide nucleic acids (PNAs) and for peptoid synthesis . Fmoc-Aeg(N3)-OH is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-151828
-
|
|
|
Azide
|
|
N3-Gly-Aeg(Fmoc)-OH is a click chemistry reagent containing an azide group. PNA building-block that can be further modified using Click-chemistry . It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
|
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