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ovarian dysfunction

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Akt (1) Apoptosis (2) Arginase (1) Atg8/LC3 (1) Autophagy (1) Bcl-2 Family (1) Biochemical Assay Reagents (2) Cadherin (1) EGFR (1) Endogenous Metabolite (1) ERK (2) Estrogen Receptor/ERR (3) mTOR (1) NF-κB (1) p62 (1) PARP (1) Reactive Oxygen Species (ROS) (5) TGF-beta/Smad (1) TGF-β Receptor (1) Wnt (1) β-catenin (1)
By Research Areas:	Cancer (3) Endocrinology (3) Inflammation/Immunology (5) Metabolic Disease (4)

Inhibitors & Agonists

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Isotope-Labeled Compounds

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-N7106

Dimethyl phthalate DMP	Biochemical Assay Reagents Apoptosis Reactive Oxygen Species (ROS)	Inflammation/Immunology
Dimethyl phthalate (DMP) can be used as a plasticizer to impart flexibility to rigid polyvinyl chloride (PVC) resin. Additionally, Dimethyl phthalate is an oral active endocrine disruptor that can cause ovarian dysfunction in mice. Dimethyl phthalate can also induce oxidative stress and apoptosis in cells, thereby affecting blood and red blood cell function in rats .

HY-118861

Enclomiphene 4 Publications Verification (E)-Clomiphene; trans-Clomiphene; Enclomifene	Estrogen Receptor/ERR	Metabolic Disease Endocrinology
Enclomiphene ((E)-Clomiphene) is a potent and orally active non-steroidal estrogen receptor antagonist, with antioestrogenic property. Enclomiphene can be used for the research of ovarian dysfunction, testosterone deficiency, male hypogonadism and type 2 diabetes .

HY-118861A

Enclomiphene citrate 1 Publications Verification (E)-Clomiphene citrate; trans-Clomiphene citrate; Enclomifene citrate	Estrogen Receptor/ERR	Metabolic Disease Endocrinology
Enclomiphene ((E)-Clomiphene) citrate is a potent and orally active non-steroidal estrogen receptor antagonist, with antioestrogenic property. Enclomiphene citrate can be used for the research of ovarian dysfunction, testosterone deficiency, male hypogonadism and type 2 diabetes .

HY-112234

L-Sepiapterin Sepiapterin	Endogenous Metabolite	Cancer
L-Sepiapterin (Sepiapterin) is a precursor of the endothelial nitric oxide synthase (eNOS) cofactor tetrahydrobiopterin (BH4). L-Sepiapterin improves endothelial dysfunction in small mesenteric arteries from db/db mice, and induces angiogenesis. L-Sepiapterin inhibits cell proliferation and migration of ovarian cancer cells via down-regulation of p70 ^S6K-dependent VEGFR-2 expression .

HY-W142432

Perfluoroundecanoic acid	Biochemical Assay Reagents β-catenin Wnt Arginase TGF-beta/Smad mTOR Akt ERK Atg8/LC3 p62 Autophagy	Metabolic Disease Inflammation/Immunology Cancer
Perfluoroundecanoic acid is a perfluoroalkyl substance (PFAS). Perfluoroundecanoic acid is an orally active oxidative stress inducer. Perfluoroundecanoic acid promotes macrophage M2 polarization, activates Wnt/β-catenin signaling and enhances β-catenin nuclear accumulation. Perfluoroundecanoic acid -induced M2 phenotype macrophage accelerates tumor progression in vitro and in vivo. Perfluoroundecanoic acid induces DNA damage, reproductive and pathophysiological dysfunctions via oxidative stress in male Swiss mice. Perfluoroundecanoic acid inhibits Leydig cell development in pubertal male rats via inducing oxidative stress and autophagy. Perfluoroundecanoic acid accelerates insulitis development in a mouse model of type 1 diabetes. Perfluoroundecanoic acid can be used for the study of ovarian cancer, type 1 diabetes and inflammation .

HY-118861B

Enclomiphene hydrochloride (E)-Clomiphene hydrochloride; trans-Clomiphene hydrochloride; Enclomifene hydrochloride	Estrogen Receptor/ERR	Metabolic Disease Endocrinology
Enclomiphene ((E)-Clomiphene) hydrochloride is a potent and orally active non-steroidal estrogen receptor antagonist, with antioestrogenic property. Enclomiphene hydrochloride can be used for the research of ovarian dysfunction, testosterone deficiency, male hypogonadism and type 2 diabetes .

HY-W778335

Dimethyl Phthalate-13C2 DMP-¹³C₂	Reactive Oxygen Species (ROS)	Inflammation/Immunology
Dimethyl Phthalate- ¹³C₂ (DMP- ¹³C₂) is the ¹³C-labeled Dimethyl phthalate (HY-N7106). Dimethyl phthalate (DMP) can be used as a plasticizer to impart flexibility to rigid polyvinyl chloride (PVC) resin. Additionally, Dimethyl phthalate is an oral active endocrine disruptor that can cause ovarian dysfunction in mice. Dimethyl phthalate can also induce oxidative stress and apoptosis in cells, thereby affecting blood and red blood cell function in rats .

HY-N7106S3

Dimethyl phthalate-13C6 DMP-¹³C₆	Reactive Oxygen Species (ROS)	Inflammation/Immunology
Dimethyl phthalate- ¹³C₆ (DMP- ¹³C₆) is the ¹³C-labeled Dimethyl phthalate (HY-N7106). Dimethyl phthalate (DMP) can be used as a plasticizer to impart flexibility to rigid polyvinyl chloride (PVC) resin. Additionally, Dimethyl phthalate is an oral active endocrine disruptor that can cause ovarian dysfunction in mice. Dimethyl phthalate can also induce oxidative stress and apoptosis in cells, thereby affecting blood and red blood cell function in rats .

HY-175257

Theophylline-platinum(IV) prodrug-1	PARP Reactive Oxygen Species (ROS) Apoptosis NF-κB ERK Bcl-2 Family TGF-β Receptor EGFR Cadherin	Cancer
Theophylline-platinum(IV) prodrug-1 is a PARP-1 inhibitor. Theophylline-platinum(IV) prodrug-1 enhances DNA damage, ROS production, mitochondrial dysfunction, apoptosis and S-phase arrest, along with reducing invasion and metastasis in cells. Theophylline-platinum(IV) prodrug-1 exhibits superior antitumor activity in the xenograft SKOV3-BRCA1-KD tumor model. Theophylline-platinum(IV) prodrug-1 can be used for the study of ovarian cancer .

HY-N7106S2

Dimethyl phthalate-13C6,d4 DMP-¹³C₆,d₄	Reactive Oxygen Species (ROS)	Inflammation/Immunology
Dimethyl phthalate- ¹³C₆,d₄ (DMP- ¹³C₆,d₄) is the deuterium labeled and ¹³C-labeled Dimethyl phthalate (HY-N7106). Dimethyl phthalate (DMP) can be used as a plasticizer to impart flexibility to rigid polyvinyl chloride (PVC) resin. Additionally, Dimethyl phthalate is an oral active endocrine disruptor that can cause ovarian dysfunction in mice. Dimethyl phthalate can also induce oxidative stress and apoptosis in cells, thereby affecting blood and red blood cell function in rats .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-N7106

Dimethyl phthalate DMP	Structural Classification Natural Products Microorganisms other families Animals Classification of Application Fields Source classification Other Diseases Plants Disease Research Fields	Biochemical Assay Reagents Apoptosis Reactive Oxygen Species (ROS)
Dimethyl phthalate (DMP) can be used as a plasticizer to impart flexibility to rigid polyvinyl chloride (PVC) resin. Additionally, Dimethyl phthalate is an oral active endocrine disruptor that can cause ovarian dysfunction in mice. Dimethyl phthalate can also induce oxidative stress and apoptosis in cells, thereby affecting blood and red blood cell function in rats .

HY-112234

L-Sepiapterin Sepiapterin	Alkaloids Structural Classification Classification of Application Fields Other Alkaloids Source classification Endogenous metabolite Disease Research Fields Cancer	Endogenous Metabolite
L-Sepiapterin (Sepiapterin) is a precursor of the endothelial nitric oxide synthase (eNOS) cofactor tetrahydrobiopterin (BH4). L-Sepiapterin improves endothelial dysfunction in small mesenteric arteries from db/db mice, and induces angiogenesis. L-Sepiapterin inhibits cell proliferation and migration of ovarian cancer cells via down-regulation of p70 ^S6K-dependent VEGFR-2 expression .

Cat. No.	Product Name	Chemical Structure

HY-W778335

Dimethyl Phthalate-13C2
Dimethyl Phthalate- ¹³C₂ (DMP- ¹³C₂) is the ¹³C-labeled Dimethyl phthalate (HY-N7106). Dimethyl phthalate (DMP) can be used as a plasticizer to impart flexibility to rigid polyvinyl chloride (PVC) resin. Additionally, Dimethyl phthalate is an oral active endocrine disruptor that can cause ovarian dysfunction in mice. Dimethyl phthalate can also induce oxidative stress and apoptosis in cells, thereby affecting blood and red blood cell function in rats .

Dimethyl Phthalate-13C2

Dimethyl Phthalate- ¹³C₂ (DMP- ¹³C₂) is the ¹³C-labeled Dimethyl phthalate (HY-N7106). Dimethyl phthalate (DMP) can be used as a plasticizer to impart flexibility to rigid polyvinyl chloride (PVC) resin. Additionally, Dimethyl phthalate is an oral active endocrine disruptor that can cause ovarian dysfunction in mice. Dimethyl phthalate can also induce oxidative stress and apoptosis in cells, thereby affecting blood and red blood cell function in rats .

HY-N7106S3

Dimethyl phthalate-13C6
Dimethyl phthalate- ¹³C₆ (DMP- ¹³C₆) is the ¹³C-labeled Dimethyl phthalate (HY-N7106). Dimethyl phthalate (DMP) can be used as a plasticizer to impart flexibility to rigid polyvinyl chloride (PVC) resin. Additionally, Dimethyl phthalate is an oral active endocrine disruptor that can cause ovarian dysfunction in mice. Dimethyl phthalate can also induce oxidative stress and apoptosis in cells, thereby affecting blood and red blood cell function in rats .

Dimethyl phthalate-13C6

Dimethyl phthalate- ¹³C₆ (DMP- ¹³C₆) is the ¹³C-labeled Dimethyl phthalate (HY-N7106). Dimethyl phthalate (DMP) can be used as a plasticizer to impart flexibility to rigid polyvinyl chloride (PVC) resin. Additionally, Dimethyl phthalate is an oral active endocrine disruptor that can cause ovarian dysfunction in mice. Dimethyl phthalate can also induce oxidative stress and apoptosis in cells, thereby affecting blood and red blood cell function in rats .

HY-N7106S2

Dimethyl phthalate-13C6,d4
Dimethyl phthalate- ¹³C₆,d₄ (DMP- ¹³C₆,d₄) is the deuterium labeled and ¹³C-labeled Dimethyl phthalate (HY-N7106). Dimethyl phthalate (DMP) can be used as a plasticizer to impart flexibility to rigid polyvinyl chloride (PVC) resin. Additionally, Dimethyl phthalate is an oral active endocrine disruptor that can cause ovarian dysfunction in mice. Dimethyl phthalate can also induce oxidative stress and apoptosis in cells, thereby affecting blood and red blood cell function in rats .

Dimethyl phthalate-13C6,d4

Dimethyl phthalate- ¹³C₆,d₄ (DMP- ¹³C₆,d₄) is the deuterium labeled and ¹³C-labeled Dimethyl phthalate (HY-N7106). Dimethyl phthalate (DMP) can be used as a plasticizer to impart flexibility to rigid polyvinyl chloride (PVC) resin. Additionally, Dimethyl phthalate is an oral active endocrine disruptor that can cause ovarian dysfunction in mice. Dimethyl phthalate can also induce oxidative stress and apoptosis in cells, thereby affecting blood and red blood cell function in rats .

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