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ophthalmic agents

" in MedChemExpress (MCE) Product Catalog:

12

Inhibitors & Agonists

4

Fluorescent Dye

2

Peptides

2

Isotope-Labeled Compounds

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-133026

    N-Acetyl-L-carnosine

    Drug Intermediate Endogenous Metabolite Inflammation/Immunology
    N-Acetylcarnosine, a natural histidine-containing dipeptide, is a source of pharmacological principal L-carnosine. N-Acetylcarnosine is a potent ophthalmic agent in human cataracts .
    N-Acetylcarnosine
  • HY-D0711
    Indocyanine green
    30+ Cited Publications

    Foxgreen; IC Green; Cardiogreen

    Fluorescent Dye Cancer
    Indocyanine green (Foxgreen) is a low toxicic fluorescent agent that has been widely used in medical diagnostics, such as determining cardiac output, hepatic function, and liver blood flow, and for ophthalmic angiography (Ex/Em = 785/813 nm) .
    Indocyanine green
  • HY-100543
    Zenidolol
    Maximum Cited Publications
    41 Publications Verification

    ICI-118551

    Adrenergic Receptor Inflammation/Immunology
    Zenidolol (ICI-118551) is a selective β2 adrenergic receptor antagonist. Zenidolol inhibits β2-, β1- and β3-adrenergic receptor with Ki values of 0.7, 49.5 and 611 nM, respectively. Zenidolol can be used as an ocular hypotensive agent used for ophthalmic disease research .
    Zenidolol
  • HY-D0214R

    Reference Standards Influenza Virus Others
    Rose Bengal (sodium) (Standard) is the analytical standard of Rose Bengal (sodium). This product is intended for research and analytical applications. Rose Bengal sodium, a synthetic fluorescein derivative, and is a crimson-coloured dye with the principal component being 4,5,6,7-tetrachloro-2,4,5,7-tetraiodo fluorescein. Rose Bengal sodium has been widely used as an ophthalmic diagnostic agents, and can detect desiccated or damaged cells on the ocular surface. Rose Bengal sodium exhibits antiviral activities .
    Rose Bengal sodium (Standard)
  • HY-D0214
    Rose Bengal sodium
    1 Publications Verification

    Influenza Virus Photosensitizer Amyloid-β Infection Neurological Disease Cancer
    Rose Bengal sodium, a synthetic fluorescein derivative, is a deep red dye primarily composed of 4,5,6,7-tetrachloro-2,4,5,7-tetraiodo fluorescein. It is widely used as an ophthalmic diagnostic agent to detect dry or damaged cells on the ocular surface. Rose Bengal sodium exhibits antitumor activity and can inhibit Friend Leukemia Virus (FLV) infection through photodynamic action. Additionally, Rose Bengal sodium can inhibit aggregation through light irradiation. Rose Bengal sodium holds potential for use in cancer, viral infections, and neurodegenerative disease research .
    Rose Bengal sodium
  • HY-17357

    AHR 9434; AL 6515

    COX Prostaglandin Receptor Endogenous Metabolite Neurological Disease Inflammation/Immunology Endocrinology Cancer
    Nepafenac (AHR 9434; AL 6515), a nonsteroidal anti-inflammatory agent, is a topically administered COX-2 inhibitor with an IC50 of 0.12 μM. Nepafenac exhibits only weak COX-1 inhibitory activity (IC50 = 64.3 μM). Nepafenac possesses unique prodrug properties, which enable it to rapidly convert into the active metabolite Amfenac (HY-17479) in the ocular tissues, thereby achieving high concentrations in the retina and choroid. Nepafenac reduces inflammation and pain by inhibiting the activity of cyclooxygenase (COX) enzymes and thereby decreasing the production of prostaglandin PGE. Nepafenac can delay the metastasis of uveal melanoma (UM) in rabbit eyes. Nepafenac is mainly used for pain management and inflammation control after ophthalmic surgeries .
    Nepafenac
  • HY-16183

    Echothiophate iodide

    Cholinesterase (ChE) Neurological Disease
    Echothiopate iodide is a potent hBChE (human butyrylcholinesterase) inhibitor. Echothiopate iodide is a long-acting anticholinesterase agent. Echothiopate iodide can be used for glaucoma research .
    Echothiopate iodide
  • HY-133026R

    Drug Intermediate Endogenous Metabolite Inflammation/Immunology
    N-Acetylcarnosine (Standard) is the analytical standard of N-Acetylcarnosine. This product is intended for research and analytical applications. N-Acetylcarnosine, a natural histidine-containing dipeptide, is a source of pharmacological principal L-carnosine. N-Acetylcarnosine is a potent ophthalmic agent in human cataracts .
    N-Acetylcarnosine (Standard)
  • HY-D0711R

    Foxgreen (Standard); IC Green (Standard); Cardiogreen (Standard)

    Fluorescent Dye Reference Standards Others
    Indocyanine green (Standard) is the analytical standard of Indocyanine green. This product is intended for research and analytical applications. Indocyanine green (Foxgreen) is a low toxicic fluorescent agent that has been widely used in medical diagnostics, such as determining cardiac output, hepatic function, and liver blood flow, and for ophthalmic angiography .
    Indocyanine green (Standard)
  • HY-D0711S2

    Foxgreen-d7; IC Green-d7; Cardiogreen-d7

    Isotope-Labeled Compounds Fluorescent Dye Others
    Indocyanine green-d7 (Foxgreen-d7) is the deuterium labeled Indocyanine green (HY-D0711). Indocyanine green is a low toxicic fluorescent agent that has been widely used in medical diagnostics, such as determining cardiac output, hepatic function, and liver blood flow, and for ophthalmic angiography .
    Indocyanine green-d7
  • HY-17357R

    AHR 9434 (Standard); AL 6515 (Standard)

    Reference Standards COX Prostaglandin Receptor Endogenous Metabolite Neurological Disease Inflammation/Immunology Endocrinology Cancer
    Nepafenac (AHR 9434; AL 6515) (Standard) is the analytical standard of Nepafenac (HY-17357). This product is intended for research and analytical applications. Nepafenac, a nonsteroidal anti-inflammatory agent, is a topically administered COX-2 inhibitor with an IC50 of 0.12 μM. Nepafenac exhibits only weak COX-1 inhibitory activity (IC50 = 64.3 μM). Nepafenac possesses unique prodrug properties, which enable it to rapidly convert into the active metabolite Amfenac (HY-17479) in the ocular tissues, thereby achieving high concentrations in the retina and choroid. Nepafenac reduces inflammation and pain by inhibiting the activity of cyclooxygenase (COX) enzymes and thereby decreasing the production of prostaglandin PGE. Nepafenac can delay the metastasis of uveal melanoma (UM) in rabbit eyes. Nepafenac is mainly used for pain management and inflammation control after ophthalmic surgeries.
    Nepafenac (Standard)
  • HY-17357S

    AHR-9434-d5; AL-6515-d5

    Isotope-Labeled Compounds COX Prostaglandin Receptor Endogenous Metabolite Neurological Disease Inflammation/Immunology Endocrinology Cancer
    Nepafenac-d5 (AHR-9434-d5; AL-6515-d5) is the deuterium labeled Nepafenac (HY-17357). Nepafenac, a nonsteroidal anti-inflammatory agent, is a topically administered COX-2 inhibitor with an IC50 of 0.12 μM. Nepafenac exhibits only weak COX-1 inhibitory activity (IC50 = 64.3 μM). Nepafenac possesses unique prodrug properties, which enable it to rapidly convert into the active metabolite Amfenac (HY-17479) in the ocular tissues, thereby achieving high concentrations in the retina and choroid. Nepafenac reduces inflammation and pain by inhibiting the activity of cyclooxygenase (COX) enzymes and thereby decreasing the production of prostaglandin PGE. Nepafenac can delay the metastasis of uveal melanoma (UM) in rabbit eyes. Nepafenac is mainly used for pain management and inflammation control after ophthalmic surgeries.
    Nepafenac-d5

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