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Results for "

nitriles

" in MedChemExpress (MCE) Product Catalog:

14

Inhibitors & Agonists

1

Screening Libraries

2

Natural
Products

1

Click Chemistry

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-Y1416
    3-(1-Cyanoethyl)benzoic acid

    DF2107Y

    		 Biochemical Assay Reagents Others
    3-(1-Cyanoethyl)benzoic acid (DF2107Y) is a benzoic acid that can be used to screen cobalt containing nitrile hydratases (NHases) .
    3-(1-Cyanoethyl)benzoic acid
  • HY-129123
    ML318

    		Antibiotic Infection
    ML318 is a biaryl nitrile inhibitor of PvdQ acylase with an IC50 of 20 nM by binding in the acyl-binding site. ML318 inhibits P. aeruginosa (PAO1) with an IC50 of 19 μM. ML318 prevents pyoverdine production and limits the growth of P. aeruginosa under iron-limiting conditions .
    ML318
  • HY-125773
    β-cyano-L-Alanine

    Beta-cyano-l-alanine

    		 Endogenous Metabolite Neurological Disease
    β-cyano-L-Alanine (Beta-cyano-l-alanine), a nitrile of widespread occurrence in higher plants, is enzymatically produced by cyanoalanine synthase from cyanide and cysteine as substrates . β-cyano-L-Alanine abolishes the protective effect of ethanol on cerebral ischemia/reperfusion (I/R) injury .
    β-cyano-L-Alanine
  • HY-127052
    Stearonitrile

    Octadecanonitrile

    		 Others Others
    Stearonitrile is a stearic nitrile that can undergo hydrogenation reactions .
    Stearonitrile
  • HY-Y1416R
    3-(1-Cyanoethyl)benzoic acid (Standard)

    		Biochemical Assay Reagents Others
    3-(1-Cyanoethyl)benzoic acid (Standard) is the analytical standard of 3-(1-Cyanoethyl)benzoic acid. This product is intended for research and analytical applications. 3-(1-Cyanoethyl)benzoic acid (DF2107Y) is a benzoic acid that can be used to screen cobalt containing nitrile hydratases (NHases) .
    3-(1-Cyanoethyl)benzoic acid (Standard)
  • HY-130657
    m-PEG5-nitrile

    		PROTAC Linkers Cancer
    m-PEG5-nitrile is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.
    m-PEG5-nitrile
  • HY-141245
    Hydroxy-PEG4-C2-nitrile

    		PROTAC Linkers Cancer
    Hydroxy-PEG4-C2-nitrile is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
    Hydroxy-PEG4-C2-nitrile
  • HY-W440817
    4,4-Bis(octyloxy)butanenitrile

    		Biochemical Assay Reagents Others
    4,4-Bis(octyloxy)butanenitrile is a lipid building block with a terminal nitrile group. The nitrile group can undergo hydrolysis, reduction, and other reactions.
    4,4-Bis(octyloxy)butanenitrile
  • HY-140842
    Azido-PEG4-nitrile

    		PROTAC Linkers Cancer
    Azido-PEG4-nitrile is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG4-nitrile is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
    Azido-PEG4-nitrile
  • HY-113811
    Diisopropyl xanthogen disulfide

    DIXDS; Diproxide

    		 Biochemical Assay Reagents Others
    Diisopropyl xanthogen disulfide (DIXDS) is a superaccelerator for natural rubber and latex, styrene-butadiene rubber and latex, nitrile butadiene rubber and recycled rubber. It can also be used as a neoprene rubber modifier and an insoluble sulfur stabilizer .
    Diisopropyl xanthogen disulfide
  • HY-120631A
    BMS-538305 hydrochloride

    		Dipeptidyl Peptidase Others
    BMS-538305 hydrochloride is a potent and selective inhibitor of dipeptidyl peptidase IV (DPP-IV), exhibiting strong biological activity by forming a reversible covalent complex with the enzyme. BMS-538305 hydrochloride demonstrates its mechanism of action through the covalent attachment between the nitrile carbon of the inhibitor and the enzyme residue S630, as unveiled by the X-ray crystal structure analysis.
    BMS-538305 hydrochloride
  • HY-14292
    NVP-DPP728

    		Dipeptidyl Peptidase Metabolic Disease
    NVP-DPP728 is a potent, reversible and nitrile-dependent dipeptidyl peptidase IV (DPP-IV) inhibitor. NVP-DPP728 can inhibit human DPP-IV amidolytic activity with a Ki of 11 nM. NVP-DPP728 inhibits degradation of glucagon-like peptide-1 (GLP-1) and thereby potentiates insulin release in response to glucose intake. NVP-DPP728 can be used for researching diabetes .
    NVP-DPP728
  • HY-138153
    JKE-1674
    3 Publications Verification

    		 Glutathione Peroxidase Ferroptosis Cancer
    JKE-1674 is an orally active glutathione peroxidase 4 (GPX4) inhibitor and an active metabolite of GPX4 inhibitor ML-210. JKE-1674, an analog of ML-210 in which the nitroisoxazole ring is replaced with an α-nitroketoxime. JKE-1674 can convert into a nitrile oxide JKE-1777. JKE-1674 kills LOX-IMVI cells in a manner that is equipotent to ML-210 and is completely rescued by ferroptosis inhibitors .
    JKE-1674
  • HY-N6742
    Borrelidin
    1 Publications Verification

    Treponemycin

    		 CDK Parasite Apoptosis Antibiotic Infection
    Borrelidin (Treponemycin) is a bacterial and eukaryal threonyl-tRNA synthetase inhibitor which is a nitrile-containing macrolide antibiotic isolated from Streptomyces rochei . Borrelidin is an inhibitor of Cdc28/Cln2 of the budding yeast, with an IC50 of 24 μM . Borrelidin is a potent angiogenesis inhibitor, with an IC50 of 0.8 nM. Borrelidin induces apoptosis in the tube-forming cells . Borrelidin has strong antimalarial activities, with IC50s of 1.9 nM and 1.8 nM against K1 and FCR3 strains of Plasmodium falciparum, respectively .
    Borrelidin

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