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nanoscale

" in MedChemExpress (MCE) Product Catalog:

12

Inhibitors & Agonists

4

Fluorescent Dye

3

Biochemical Assay Reagents

1

Isotope-Labeled Compounds

1

Click Chemistry

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-D2465

    Fluorescent Dye Others
    CY5-Dextran is a fluorescent dye CY5 (HY-D0821)- labeled Dextran (HY-112624). CY5 exhibits a maximal excitation wavelength of 633 nm, and a maximal emission wavelength of 670 nm. Dextran-CY5 can be used to visualize the specific subcellular distribution of dextran at the nanoscale .
    CY5-Dextran (MW60-80k)
  • HY-140696D

    mPEG-Hydroxy (MW 10000); Polyethylene glycol monomethyl ether (MW 10000)

    PROTAC Linkers Cancer
    m-PEG-OH (MW 10000) can be used as a macroinitiator to participate in the synthesis of amphiphilic block copolymers. Amphiphilic block copolymers can be used to prepare nanoscale micelles to deliver active drugs. Paclitaxel (HY-B0015), a hydrophobic anticancer agent encapsulated in micelles, has stronger activity in killing cancer cells than free Paclitaxel. And it preferentially accumulates in tumor tissue with only limited distribution in healthy organs.
    m-PEG-OH (MW 10000)
  • HY-140696E

    mPEG-Hydroxy (MW 1000); Polyethylene glycol monomethyl ether (MW 1000)

    PROTAC Linkers Cancer
    m-PEG-OH (MW 1000) can be used as a macroinitiator to participate in the synthesis of amphiphilic block copolymers. Amphiphilic block copolymers can be used to prepare nanoscale micelles to deliver active drugs. Paclitaxel (HY-B0015), a hydrophobic anticancer agent encapsulated in micelles, has stronger cancer-killing activity than free Paclitaxel. And it accumulates preferentially in tumor tissues and has only limited distribution in healthy organs.
    m-PEG-OH (MW 1000)
  • HY-152901

    Fluorescent Dye Others
    Chol-N3 is a bioorthogonal-based chol probe. Chol-N3 can combine with super-resolution fluorescence microscopy (SRM), providing direct visualization of nanoscale lipid heterogeneity in the cell surface of resting living cells . Chol-N3 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
    Chol-N3
  • HY-D1173

    Fluorescent Dye
    Acid blue 113 is an azo dye whose staining effect is effectively removed by nanoscale zero-valent iron (NZVI) particles.
    Acid blue 113
  • HY-D1121

    Fluorescent Dye
    Acid black 24 is a black agent whose staining effect is effectively removed by nanoscale zero-valent iron (NZVI) particles. The maximum unit removal capacity is 609.4 mg of dye per gram of NZVI.
    Acid black 24
  • HY-134939

    Drug Derivative Others
    thio-Miltefosine is a modulator of rafts in membrane tissue. Rafts are nanoscale aggregates of different lipids and proteins that profoundly affect cellular function. Thio-Miltefosine modulates membrane phase behavior on cell-derived giant plasma membrane vesicles .
    thio-Miltefosine
  • HY-140696C

    mPEG-Hydroxy (MW 20000); Polyethylene glycol monomethyl ether (MW 20000)

    PROTAC Linkers Cancer
    m-PEG-OH (MW 20000) can be used as a macroinitiator to participate in the synthesis of amphiphilic block copolymers. Nanoscale micelles can be prepared by using amphiphilic block copolymers to deliver active drugs. Paclitaxel (HY-B0015), a hydrophobic anticancer agent encapsulated in micelles, has stronger activity in killing cancer cells than free Paclitaxel. And it preferentially accumulates in tumor tissue with only limited distribution in healthy organs.
    m-PEG-OH (MW 20000)
  • HY-112624F1

    Fluorescent Dye Cancer
    CY5-Dextran (MW 4000) is a fluorescent dye that consists of CY5 (HY-D0821) and Dextran (HY-112624) (Ex=633 nm; Em=670 nm). CY5-Dextran (MW 4000) exhibits an anti-tumor effect. CY5-Dextran (MW 4000) can be used to visualize the specific subcellular distribution of dextran at the nanoscale .
    CY5-Dextran (MW 4000)
  • HY-176347S

    Isotope-Labeled Compounds Cancer
    Alpha Feto Protein, Arg- 13C36, 15N4, Lys- 13C6, 15N2 is the 13C- and 15N-labeled Alpha Feto Protein.
    Alpha Feto Protein, Arg-13C6,15N4, Lys-13C6,15N2
  • HY-162828

    STAT HDAC Cancer
    STAT3/HDAC-IN-2 (compound 18) is a dual inhibitor of STAT3 and HDAC, inducing autophagy and apoptosis. STAT3/HDAC-IN-2 is an amphiphilic hydroxamic acid hybrid based on the natural product isopropanol lactone (IAL) and is a nanoscale anticancer agent. STAT3/HDAC-IN-2 can self-assemble in water to form nanoparticles, which have higher tumor tissue accumulation, cellular uptake and anticancer properties compared to the free state .
    STAT3/HDAC-IN-2
  • HY-132828

    LT3001; DHDMIQK(KAP)

    P-selectin Cardiovascular Disease Metabolic Disease Inflammation/Immunology
    Odatroltide (LT3001; DHDMIQK(KAP)) is a P-selectin inhibitor. Odatroltide is a peptide molecule comprising a tripeptide Pro-Ala-Lys (PAK) and an (S)-6,7-dihydroxy-1,1-dimethyl-1,2,3,4-tetrahydro-isoquinoline-3-carboxylic acid domain. Odatroltide can restore cerebral blood flow, scavenge free radicals, and inhibit leukocyte migration. Odatroltide possesses thrombolytic and anti-thrombotic activities .
    Odatroltide

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